Fort Myers River District Vacations from $733

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Your Fort Myers River District Vacation

Experience the best that Fort Myers River District has to offer with a tailor-made Fort Myers River District vacation package. From its markets and nightlife to its cafes, get ready to fall for the charms of this food-lovers neighborhood. When it's time to sightsee, you'll find lots of big-name attractions nearby including Edison and Ford Winter Estates, Imaginarium Hands - On Museum and Edison Mall. Visit one, two or all during your trip to Fort Myers River District. Don't just think about it — make it a reality! Secure your ideal Fort Myers River District vacation with Expedia and experience travel your way.

The Latest Fort Myers River District Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

Save 100% on your flight
$733
per person
Nov 5 - Nov 9
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
8.6/10 Excellent! (1,787 reviews)
Mariners Boathouse by Coolvacay

Mariners Boathouse by Coolvacay

South Island
Save 100% on your flight
$1,005
per person
Nov 28 - Dec 4
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
9.8/10 Exceptional! (13 reviews)
Very nice place, our 2nd time here and we still love it

Reviewed on Sep 7, 2026

Harbour House At The Inn

Harbour House At The Inn

Save 100% on your flight
$997
per person
Nov 28 - Dec 4
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
9.2/10 Wonderful! (780 reviews)
Easy check-in. Very clean. Quiet. Unit has everything you need. I stay here often and will continue.

Reviewed on Sep 20, 2026

Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

Save 100% on your flight
$956
per person
Nov 5 - Nov 9
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
9.2/10 Wonderful! (1,012 reviews)
If you are looking for a relaxing vacation at a quiet, family-friendly hotel offering quality and good amenities, this is the ideal choice. It features a shuttle service to a private beach, as well as a small pool area and a lazy river that are perfect for families.

Reviewed on Sep 22, 2026

Marco Polo by Avantstay Waterfront 5bdr, Pool, Spa, Fire Pit, Walk to Beach

Marco Polo by Avantstay Waterfront 5bdr, Pool, Spa, Fire Pit, Walk to Beach

South End
Save 100% on your flight
$3,318
per person
Dec 14 - Dec 19
found 19 hours ago
Roundtrip flight included
Philadelphia (PHL) to Fort Myers (RSW)
No reviews

Where to stay in Fort Myers River District

Find the best Fort Myers River District areas and neighborhoods for the activities you enjoy most. Learn more about Fort Myers River District
An aerial view of a coastal area with a bridge connecting two land masses, a beach, and a clear blue sky.

Iona

While visiting Iona, you might make a stop by sights like Estero Bay Preserve State Park and Tribby Arts Center.

Find hotels in Iona
A beach at sunset with the sun reflecting on the water, palm trees, and a clear sky.

Villas

1 out of top 10 points of interest in this area

The beaches and abundant dining options are top of the list for many visitors to Villas. A stop by Bell Tower Shops or Regal Belltower might round out your trip.

Find hotels in Villas
A bridge over water with a clear sky.

Punta Rassa

1 out of top 10 points of interest in this area

Punta Rassa is a destination visitors seek out for is beaches, abundant dining options, and waterfront views. You might want to check out attractions like Sanibel Harbour or Sanibel Harbour Beach while you're exploring the neighborhood.

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A pier extending into the water with two gazebos at the end, under a sunset sky.

South Fort Myers

While visiting South Fort Myers, you might make a stop by sights like Estero Bay Preserve State Park and Castle Golf.

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A pier extending into the water with two gazebos at the end, under a sunset sky.

Daniels Corridor

2 out of top 10 points of interest in this area

While visiting Daniels Corridor, you might make a stop by sights like Six Mile Cypress Slough Preserve and Lee Health Sports Complex.

Find hotels in Daniels Corridor

Fort Myers River District Hotel Deals

Luminary Hotel & Co., Autograph Collection

Luminary Hotel & Co., Autograph Collection

2200 Edwards Drive Fort Myers FL
Fully refundableReserve now, pay when you stay
$183 nightly
$204 total
Oct 8 - Oct 9
Total with taxes and fees
Luminary Hotel & Co., Autograph Collection
Hampton Inn Fort Myers Downtown

Hampton Inn Fort Myers Downtown

2151 Johnson Street Fort Myers FL
Fully refundableReserve now, pay when you stay
$98 nightly
$109 total
Oct 4 - Oct 5
Total with taxes and fees
9.2/10 Wonderful! (1,048 reviews)
"Great staff and good breakfast and the rooms were fine and that’s what you could expect for your money"

Reviewed on Sep 25, 2026

Hampton Inn Fort Myers Downtown
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
$53 nightly
$59 total
Sep 26 - Sep 27
Total with taxes and fees
Baymont by Wyndham Fort Myers Central
See all 13,947 properties in Fort Myers River District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Fort Myers River District attractions

A red sculpture in a park with palm trees and a building in the background.

Centennial Park

8.2/10 (185 reviews)
Just minutes from Fort Myers’ historic downtown district, this park’s centerpiece is the statue honoring three of the city’s most famous citizens.
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A Florida Repurtry Theatre with a teal awning, palm trees, and a parked bicycle.

Florida Repertory Theater

10.0/10 (1 review)
You can enjoy a show at Florida Repertory Theater on your trip to Fort Myers. You can attend a baseball game while in the area.
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Sidney & Berne Davis Art Center

10.0/10 (1 review)
Enjoy an outing to Sidney & Berne Davis Art Center during your stay in Fort Myers. You can attend a baseball game while in the area.
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Fort Myers Historical Museum

10.0/10 (1 review)
You can spend time studying the exhibits at Fort Myers Historical Museum during your travels in Fort Myers. Stroll along the beautiful beaches or attend a baseball game in the area.
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Harborside Event Center

9.8/10 (6 reviews)
Learn about the events happening at Harborside Event Center during your trip to Fort Myers. You can attend a baseball game while in the area.
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Butterfly Estates

Enjoy an outing to Butterfly Estates during your stay in Fort Myers. Stroll along the beautiful beaches or attend a baseball game in the area.
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ArtFest Fort Myers

After visiting ArtFest Fort Myers, make a plan to see the other sights and activities in Fort Myers. Visit the area's shops, or simply enjoy its bars.
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Things to do

Fort Myers: Guided Standup Paddleboarding or Kayaking Tour

Fort Myers Dolphin & Manatee Kayak or Paddleboard Tour

$72
per adult
90% of travellers recommend
Fort Myers Dolphin & Manatee Kayak or Paddleboard Tour
Close-up encounters with our beautiful Dolphins

Private Dolphin & Sightseeing Boat Day Tour

$161
per adult
Private Dolphin & Sightseeing Boat Day Tour
Self-Guided Fort Myers Scavenger Hunt: His Greatest Invention

Self-Guided Fort Myers Scavenger Hunt: His Greatest Invention

$12
per adult
Self-Guided Fort Myers Scavenger Hunt: His Greatest Invention
See all activities in Fort Myers
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.