Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Grand Cayman Independent Hotels

See all 101 Hotels in Grand Cayman
Margaritaville Beach Resort Grand Cayman

Margaritaville Beach Resort Grand Cayman

269 West Bay Road, Sunset Cove, Seven Mile Beach
4.0 out of 5.0
3.7 out of 5 (87 reviews)
Wonderful Hotel This is a wonderful hotel. The room is very clean and the staff are extremely friendly and helpful. … - 

$187

$187
Sunshine Suites Resort

Sunshine Suites Resort

1465 Esterley Tibbetts, Seven Mile Beach
4.0 out of 5.0
4.4 out of 5 (1,101 reviews)
Well maintained. Very clean, and maintained. Courteous staff, very clean room, excellent Grill food. Loved the close … - 

$199

$199
Grand Caymanian Resort

Grand Caymanian Resort

278 Crighton Drive, Crystal Harbour
4.0 out of 5.0
4.0 out of 5 (55 reviews)
Perfect spot Everything was perfect, clean rooms, nice staff,perfect location. I will definitely be back - 

$120

$120
Grand Cayman Marriott Beach Resort

Grand Cayman Marriott Beach Resort

389 West Bay Road, Seven Mile Beach
4.5 out of 5.0
4.4 out of 5 (1,586 reviews)
Great snorkeling site with lots of amenities We enjoyed snorkeling off the hotel's beach area. The beach was affected by the storms but the hote … - 

$305

$305
Kimpton Seafire Resort and Spa

Kimpton Seafire Resort and Spa

60 Tanager Way, Seven Mile Beach
5.0 out of 5.0
4.9 out of 5 (182 reviews)
Luxury Beach Vacation Friendly and attentive staff. Service on par with the Ritz. Amazing food and drink. Nice little soc … - 

$509

$509
Holiday Inn Resort Grand Cayman

Holiday Inn Resort Grand Cayman

278 Crighton Drive, Crystal Harbour
4.0 out of 5.0
3.8 out of 5 (271 reviews)
Nice rooms, and grounds The rooms were huge with all the amenities needed for a family. We stayed 3 nights and found the st … - 

$199

$199
Morritts Tortuga Club

Morritts Tortuga Club

2289 Queens Highway, Grand Cayman, East End
4.0 out of 5.0
4.0 out of 5 (29 reviews)
Nice hotel close to the beach Food and drinks are pricey. The hotel is very clean and staff is wonderful. Convert money over to C … - 

$299

$299
Regal Beach Club

Regal Beach Club

431 West Bay Road, Seven Mile Beach
4.5 out of 5.0
4.7 out of 5 (7 reviews)
Excellent hotel and a perfect location Couldn’t be any better I was in 2 bedroom which is considered the smallest unit even this was about … - 
Compass Point Dive Resort

Compass Point Dive Resort

346 Austin Conolly Drive, East End
4.0 out of 5.0
4.8 out of 5 (133 reviews)
Great Vacation My husband and I spent 3 nights during the Thanksgiving weekend. We absolutely LOVE the convenience … - 
Shangri-La Boutique Bed & Breakfast

Shangri-La Boutique Bed & Breakfast

29 Sticky Toffee Lane, West Bay
4.5 out of 5.0
4.9 out of 5 (54 reviews)
Dean was awesome! Friendly and helpful. Great location. Awesome breakfast! - 

$160

$160
Villas of the Galleon

Villas of the Galleon

West Bay Road, Seven Mile Beach
3.5 out of 5.0
4.7 out of 5 (16 reviews)
Best kept secret in Cayman Islands We stayed in a one bdrm oceanfront Unit with full kitchen and daily housekeeping. Lots of shades at … - 

$470

$470
Seven Mile Beach Resort & Club

Seven Mile Beach Resort & Club

19 D Piper Way, West Bay Road, Seven Mile Beach
3.5 out of 5.0
4.3 out of 5 (82 reviews)
Will definitely go back I have nothing bad to say about this condo. It was clean the staff was super friendly. The condo ha … - 

$250

$250
Eldemire's Tropical Island Inn

Eldemire's Tropical Island Inn

18 Pebbles Way, George Town
3.5 out of 5.0
4.0 out of 5 (59 reviews)
We loved our time at Eldemire's! Eldemire's was perfect for our first visit to the Cayman's. Plenty of stuff to do within walking di … - 
The Westin Grand Cayman Seven Mile Beach Resort & Spa

The Westin Grand Cayman Seven Mile Beach Resort & Spa

Seven Mile Beach, Seven Mile Beach
5.0 out of 5.0
4.0 out of 5 (1,158 reviews)
Great renovations Updated to a true westin experience. Management and staff very friendly - 

$459

$459
Regal Beach Club 411

Regal Beach Club 411

431 West Bay Road, Seven Mile Beach
4.5 out of 5.0
5.0 out of 5 (1 reviews)
Excellent condo on seven mile beach and a bargain compared to neighboring resorts. - 
The Grandview Condos on Seven Mile Beach

The Grandview Condos on Seven Mile Beach

95 Snooze Lane, Seven Mile Beach
4.0 out of 5.0
4.8 out of 5 (33 reviews)
Beautiful and convenient location; flawless condo The grounds are highly picturesque, the pool is perfect for the little ones and the reef is wonderf … - 
Wyndham Reef Resort All - Inclusive

Wyndham Reef Resort All - Inclusive

2221 Queens Highway Colliers Bay, East End
4.0 out of 5.0
3.3 out of 5 (3 reviews)
Great hotel with snorkeling right off the beach Came for the snorkeling right off the beach and nearby scuba diving. Was pleasantly surprised how u … - 
Caribbean Club Luxury Condo Hotel

Caribbean Club Luxury Condo Hotel

871 West Bay Road, Seven Mile Beach
5.0 out of 5.0
4.9 out of 5 (16 reviews)
Fantastic location and amazing accommodations. The Caribbean Club is amazing! It is located on the best part of 7 mile beach, within walking dista … - 
World Famous Seven Mile Beach "location, Cayman Islands" Welcome to Paradise

World Famous Seven Mile Beach "location, Cayman Islands" Welcome to Paradise

537 W Bay Rd, George Town
5.0 out of 5 (22 reviews)
Aqua Bay Club Luxury Condos

Aqua Bay Club Luxury Condos

W Bay Rd, Seven Mile Beach
3.5 out of 5.0
4.8 out of 5 (27 reviews)
Nice condo and beach. Nice condo, pool, and beach. Great location away from the crowds. Also good snorkeling off the beac … - 
Map

Recently booked Grand Cayman hotels

Wyndham Reef Resort
4.0 out of 5.0
Last booking: 3 hours ago
The Ritz-Carlton, Grand Cayman
5.0 out of 5.0
Last booking: 9 hours ago
Comfort Suites Seven Mile Beach and Resort
4.0 out of 5.0
Last booking: 9 hours ago
Compass Point Dive Resort
4.0 out of 5.0
Last booking: 16 hours ago
Seven Mile Beach Resort & Club
3.5 out of 5.0
Last booking: 38 hours ago

Independent Grand Cayman Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Grand Cayman, Cayman Islands. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Grand Cayman hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Grand Cayman Independent locations may even offer extra little benefits and discounts for frequent travelers.