Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Map

Recently booked Hannibal hotels

Quincy Inn and Suites
2.0 out of 5.0
Last booking: 19 hours ago
Microtel Inn & Suites by Wyndham Quincy
2.5 out of 5.0
Last booking: 22 hours ago
Sleep Inn & Suites
2.5 out of 5.0
Last booking: 26 hours ago
Hampton Inn Quincy
2.5 out of 5.0
Last booking: 36 hours ago
Super 8 by Wyndham Hannibal
2.0 out of 5.0
Last booking: 37 hours ago
Best Western On The River
2.5 out of 5.0
Last booking: 39 hours ago
Stoney Creek Quincy
2.0 out of 5.0
Last booking: 39 hours ago
Hannibal Inn Hannibal
2.0 out of 5.0
Last booking: 39 hours ago
Quality Inn & Suites Hannibal
2.5 out of 5.0
Last booking: 39 hours ago

Best Western Hannibal Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Best Western hotels in Hannibal, Missouri. Known for well-appointed rooms and friendly, personalized service, each of the top Best Western Hannibal hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Hannibal Best Western locations may even offer extra little benefits and discounts for frequent travelers.