Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Isle of Palms ResortQuest Hotels

See all 150 Hotels in Isle of Palms
Isle of Palms and Wild Dunes by Wyndham Vacation Rentals

Isle of Palms and Wild Dunes by Wyndham Vacation Rentals

1400 Palm Blvd., Suite N, Isle Of Palms
4.0 out of 5.0
3.4 out of 5 (32 reviews)
Total Destination Resort The unit we rented was older and outdated. Plumbing was a problem. Have stayed at Wild Dunes five t … - 
Map

Recently booked Isle of Palms hotels

Wild Dunes Resort By Destination Hotels
4.5 out of 5.0
Last booking: 10 hours ago
Seaside Inn Oceanfront
3.0 out of 5.0
Last booking: 33 hours ago