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Find Hotels in Isle of Palms, Jacksonville

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Isle of Palms hotels and places to stay

Light Grey Getaway Under 2 Miles to Mayo, 4 Miles to the Beach
4.7/5Exceptional! (7 reviews)
Great location for Mayo Clinic and short trip to beaches

"Property was very cute. Worked great for my Mayo Clinic visit. Check in and home information was very accurate and accessible. Host communicated great."…"

Reviewed on Oct 10, 2020

Light Grey Getaway Under 2 Miles to Mayo, 4 Miles to the Beach
Best Western Premier Jacksonville Hotel
3.5 out of 5
4700 Salisbury Rd, Jacksonville, FL
Free CancellationReserve now, pay when you stay
The price is $77 per night from Nov 4 to Nov 5
4.4/5Excellent! (892 reviews)

"Clean comfortable modern room. Updated with everything you need."…"

Reviewed on Oct 23, 2020

Best Western Premier Jacksonville Hotel
Hyatt Regency Jacksonville
4 out of 5
225 E Coastline Dr, Jacksonville, FL
Free CancellationReserve now, pay when you stay
The price is $103 per night from Nov 23 to Nov 24
4.2/5Excellent! (1,380 reviews)

"The hotel is beautiful and well located in downtown Jacksonville. The staff is excellent and friendly. We were disappointed that our hotel room didn't include a continental breakfast- not even coffee urns in the lobby. We were told "you have coffee in your room". That coffee only provides two powdered ..."…"

Reviewed on Oct 18, 2020

Hyatt Regency Jacksonville

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Days Inn by Wyndham Jacksonville Airport
2.5 out of 5
1170 Airport Road, Jacksonville, FL
Free CancellationReserve now, pay when you stay
The price is $52 per night from Nov 8 to Nov 9
3/5 (1,029 reviews)

"They always make us feel at home and the breakfast is always on point thanks for going all out for us"…"

Reviewed on Sep 15, 2020

Days Inn by Wyndham Jacksonville Airport
Omni Jacksonville Hotel
4 out of 5
245 Water St, Jacksonville, FL
Free CancellationReserve now, pay when you stay
The price is $114 per night from Nov 8 to Nov 9
4.2/5Very Good! (1,470 reviews)

"It’s was a great trip. The room was great, I really enjoyed how we could see the river from my room. The bridge was lit up every night in blue & yellow lights for Down Syndrome."…"

Reviewed on Oct 23, 2020

Omni Jacksonville Hotel
Breathtaking Views! Intercoastal Waterfront Home w/ Pool! 1 mi. From Mayo Clinc
4.8/5Exceptional! (46 reviews)
Great place toA!

"Very nice house! Loved the pool and the whole outdoor area. Quick drive to the beach. Also beds were really comfy. Would definitely come back."…"

Reviewed on Oct 15, 2020

Breathtaking Views! Intercoastal Waterfront Home w/ Pool! 1 mi. From Mayo Clinc
The Retreat NEW TO Vrbo
Jacksonville, FL
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4.5/5Wonderful! (2 reviews)
3 wk stay

"Very convenient to Mayo Clinic"…"

Reviewed on Sep 25, 2020

The Retreat NEW TO Vrbo
The Petite Retreat NEW TO Vrbo
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5/5Exceptional! (4 reviews)
Great! Clean! Convenient!

"Perfect"…"

Reviewed on Apr 8, 2020

The Petite Retreat NEW TO Vrbo
Omni Amelia Island Resort
4 out of 5
39 Beach Lagoon Road, Fernandina Beach, FL
Free CancellationReserve now, pay when you stay
The price is $246 per night from Nov 22 to Nov 23
4.2/5Excellent! (977 reviews)

"friendly fast customer service clean room. ocean view room"…"

Reviewed on Oct 30, 2020

Omni Amelia Island Resort
The Villas of Amelia Island
4 out of 5
8 Amelia Village Circle, Amelia Island, Fernandina Beach, FL
Free CancellationReserve now, pay when you stay
The price is $220 per night from Nov 19 to Nov 20
4.1/5Very Good! (982 reviews)

"Very nice property, great for families. Room cleaning was lacking due to Covid."…"

Reviewed on Oct 6, 2020

The Villas of Amelia Island
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Isle of Palms, Jacksonville Hotel Information

Expedia.com offers a selection of 1518 hotels in Isle of Palms, Jacksonville. You are sure to find cheap deals and discount rates among them with our Price Guarantee. No matter what type of hotel strikes your fancy, we will let you search for your preferred one to accommodate your travel needs.

Expedia.com will not only save you time, but also money when booking your stay at a hotel near Isle of Palms in Jacksonville. Making reservations so you can stay within your budget is easy with us.

Expedia.com even provides you with a map so you may find hotels in the Jacksonville neighborhood you prefer.

Go ahead. Enter your travel dates to view the best offers on hotel rooms in Isle of Palms, Jacksonville now!

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Frequently asked questions

What is Isle of Palms like?
Travelers are sure to enjoy a stay in Jacksonville Beach’s Isle of Palms neighborhood.
What's a favorite place to stay in Isle of Palms?
For your stay in Isle of Palms, Light Grey Getaway Under 2 Miles to Mayo, 4 Miles to the Beach is one of the top choices based on our traveler data. Other good options for your stay in the area include The Retreat NEW TO Vrbo and Breathtaking Views! Intercoastal Waterfront Home w/ Pool! 1 mi. From Mayo Clinc.
How many hotels can I expect to find in Isle of Palms?
Expedia has 6 Isle of Palms hotels and other accommodations, and one might make a good home base for venturing out into the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes, you’ll find most hotel reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that’s non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add your dates and click on “Search”, then use the “free cancellation” filter to get top deals in Isle of Palms.
Where can I learn more about changing or cancelling my trip to Isle of Palms?
For more information about changing or cancelling your trip to Isle of Palms, head over to our customer service page.
What is there to do in this Jacksonville Beach neighborhood?
A few places to visit in the area around Isle of Palms include Jacksonville Beach Pier, Cradle Creek Preserve, and Adventure Landing. While you’re out sightseeing in Jacksonville Beach, be sure to visit other sights like Jacksonville Beach Golf Club or Windsor Parke Golf Club.

Recent reviews of Isle of Palms hotels