Issaquena County Vacations & Trips from $480

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The Latest Issaquena County Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Isle Casino Hotel Lula Hotel & Casino - A Caesars Rewards Destination

$480

per person

Dec 2 - Dec 6

found 8 hours ago

Roundtrip non-stop flight included

Columbia (CAE) to Greenville (GLH)

6.4/10 (1,000 reviews)

Nothing

Reviewed on Sep 28, 2026

Holiday Inn Express & Suites Senatobia I 55 by IHG

$576

per person

Dec 2 - Dec 6

found 8 hours ago

Roundtrip non-stop flight included

Columbia (CAE) to Greenville (GLH)

9.4/10 Exceptional! (193 reviews)

Great place to stay, just off of I-55! Clean and spacious. Kind and super-friendly staff seriously gives the atmosphere of being at a cozy B&B versus a hotel. Highly recommend!

Reviewed on Sep 20, 2026

Dreamland Inn and Suites

$498

per person

Dec 2 - Dec 6

found 8 hours ago

Roundtrip non-stop flight included

Columbia (CAE) to Greenville (GLH)

7/10 Good! (67 reviews)

Super easy! Really nice staff and always helpful.

Reviewed on Sep 25, 2026

Find the Best Issaquena County Vacation Packages

Issaquena County Essential Information

Language	English
Currency	U.S dollars
Closest Airport	Evers Intl. Airport (JAN)

Issaquena County Hotel Deals

Riverwalk Casino Hotel

1046 Warrenton Road Vicksburg MS

Fully refundableReserve now, pay when you stay

$94 nightly

$103 total

Oct 13 - Oct 14

Total with taxes and fees

8.6/10 Excellent! (1,133 reviews)

"Very nice place but so much smoking in the casino that you can barely breathe. Otherwise, it’s perfect!"

Reviewed on Sep 30, 2026

Ameristar Casino Hotel Vicksburg

4116 Washington St. Vicksburg MS

Fully refundableReserve now, pay when you stay

$37 nightly

$41 total

Oct 6 - Oct 7

Total with taxes and fees

7.4/10 Good! (1,002 reviews)

"Clean room! Friendly staff!!"

Reviewed on Oct 1, 2026

Comfort Suites Vicksburg

100 Berryman Rd Vicksburg MS

Fully refundable

$95 nightly

$105 total

Nov 1 - Nov 2

Total with taxes and fees

8.6/10 Excellent! (1,003 reviews)

"Refrigerator wasn’t cold, microwave door on the inside was really dirty, and room had a stuffy smell"

Reviewed on Oct 2, 2026

See all 134 properties in Issaquena County

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.