Beginning of main content

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Key Largo Business Hotels

See all 181 Hotels in Key Largo
Key Largo Bay Marriott Beach Resort

Key Largo Bay Marriott Beach Resort

103800 Overseas Hwy, Key Largo
4.0 out of 5.0
4.2 out of 5 (1,226 reviews)
Nice hotel, great beach and pool.Hotel was nice. We found the menu a little pricey and beach chairs were always saved in the morning with towels and items. Guests would usually return about 3 hours later. Bar and wait staff were incredible, maintenance and check in staff not overly friendly.
  Jan 5, 2018

$239

$239
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

527 Caribbean Drive, Key Largo
3.0 out of 5.0
3.6 out of 5 (1,854 reviews)
I was given a room that was to close to the bar next door. The music wasnt that bad but the late night screaming of people was terrible. If I come again I will ask not to be so close to the bar.
  Jan 22, 2018

$169

$169
Hilton Key Largo Resort

Hilton Key Largo Resort

97000 Overseas Hwy, Key Largo
4.0 out of 5.0
3.8 out of 5 (1,949 reviews)
Small beach but lots to do and hotel grounds were beautiful
  Sep 16, 2017
Bayside Inn Key Largo

Bayside Inn Key Largo

99490 Overseas Hwy, Key Largo
3.0 out of 5.0
3.0 out of 5 (1,756 reviews)
Older facility needs updating. WiFi doesn’t work. No beach to speak of. You get what you pay for. No frills
  Jan 21, 2018

$159

$159
Courtyard by Marriott Key Largo

Courtyard by Marriott Key Largo

99751 Overseas Hwy, Key Largo
3.5 out of 5.0
4.0 out of 5 (593 reviews)
Ok. Not great. Rooms were dated and needed returning.
  Jan 8, 2018

$175

$175
Holiday Inn Key Largo

Holiday Inn Key Largo

99701 Overseas Hwy, Key Largo
3.5 out of 5.0
3.9 out of 5 (1,171 reviews)
Pros -Good location and a nice pool. Cons - Room was damp and had a mold smell. The breakfast buffet was awful.
  Jan 21, 2018

$179

$179
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

102400 Overseas Hwy, Key Largo
3.0 out of 5.0
4.3 out of 5 (1,639 reviews)
We were there for a destination wedding so location was ideal.
  Jan 16, 2018

$209

$209
Mariner's Club Key Largo by KeysCaribbean

Mariner's Club Key Largo by KeysCaribbean

97501 Overseas Hwy, Key Largo
4.0 out of 5.0
3.8 out of 5 (298 reviews)
Quiet townhouseArrival was strange due to a road closure from Irma but once we got that figured out, all was well. Was hands-off but available management with some communication issues about check-in (was given wrong entry code and couldn't get in initially) but was resolved quickly with a couple phone calls.
  Oct 27, 2017
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

97450 Overseas Highway, Key Largo
4.0 out of 5.0
4.8 out of 5 (109 reviews)
Great customer service and locationOverall, really nice property. Temps were on cooler side and they did not seem to have systems or process to heat pool. Hot tub was cool water several days, then almost too hot to enjoy.
  Jan 19, 2018

$297

$297
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

99340 Overseas Highway, Key Largo
2.0 out of 5.0
3.7 out of 5 (784 reviews)
The place is rustic, and older but very nice cozy and clean. Recommend.
  Jan 21, 2018

$120

$120
Ocean Pointe Suites at Key Largo

Ocean Pointe Suites at Key Largo

500 Burton Dr, Tavernier
3.5 out of 5.0
3.8 out of 5 (2,035 reviews)
Comfortable and quaintGreat place to come and relax and enjoy the gorgeous views and weather. Great lay out of the rooms and the family areas. Thought we had missed housekeeping 3 days in a row but it was later told to me that housekeeping is only given to guests that stay for 7 days or longer😳. Luckily we are an organized ...
  Aug 3, 2017
Key West Inn Key Largo

Key West Inn Key Largo

201 Ocean Drive, Key Largo
2.5 out of 5.0
3.6 out of 5 (922 reviews)
Great location and price Last minute booking - exceeded our expectations for location and space. OverLl it’s outdated, but has some charm. We would book again.
  Jan 14, 2018

$179

$179
Sunset Cove Beach Resort

Sunset Cove Beach Resort

MM 99.5, Key Largo
3.0 out of 5.0
3.6 out of 5 (420 reviews)
Great hotel!We just stayed in the bayview room. The door puts you right on the beach. There is a multiple places to eat within walking distance. Stopped here for a few days on our way to Key West and would stay again.
  Jan 16, 2018

$150

$150
Map

Recently booked Business Hotels in Key Largo

Gilbert's Resort
2.5 out of 5.0
Last booking: 27 minutes ago
Holiday Inn Key Largo
3.5 out of 5.0
Last booking: 4 hours ago
Amy Slate's Amoray Dive Resort
2.0 out of 5.0
Last booking: 9 hours ago
Sunset Cove Beach Resort
3.0 out of 5.0
Last booking: 10 hours ago
Marina Del Mar Resort and Marina
3.0 out of 5.0
Last booking: 10 hours ago
Key Largo Bay Marriott Beach Resort
4.0 out of 5.0
Last booking: 11 hours ago
The Pelican Key Largo Cottages
2.0 out of 5.0
Last booking: 11 hours ago
Playa Largo Resort & Spa, Autograph Collection
4.0 out of 5.0
Last booking: 12 hours ago
Ed & Ellens Lodging Key largo
0.0 out of 5.0
Last booking: 17 hours ago

Pocket Guide: Business Hotels in Key Largo

Search for hotels in Key Largo on Expedia. You can easily find your hotels in Key Largo using one of the methods below:

  • View our selection of featured hotels in Key Largo
  • Use the map to find hotels in the Key Largo neighborhood you prefer
  • Use the filters to see hotels in a specific area of Key Largo, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Key Largo
  • Enter your travel dates to view the best deals on hotels in Key Largo - while they last