Find luxury hotels in Key West, FL

Most hotels are fully refundable. Because flexibility matters.

Save 10% or more on select stays with Expedia Rewards

Search over 2.9 million properties and 550 airlines worldwide.

Top Key West Luxury Hotels

H2O Suites - Adults Only
3.5 out of 5
1212 Simonton Street, Key West, FL, 33040
The price is $291 per night from Oct 2 to Oct 3
Treat yourself to a luxury stay at H2O Suites - Adults Only, where you can enjoy amenities like pillowtop beds, premium channels, and more. The spa, outdoor pool, and poolside bar are just some of the popular amenities at this deluxe hotel.
4.9/5 Exceptional! (368 reviews)
"The room was loud due to a refrigerator- made a humming sound"

Reviewed on Sep 22, 2022

Santa Maria Suites
4 out of 5
1401 Simonton St, Key West, FL, 33040
The price is $286 per night from Oct 2 to Oct 3
Treat yourself to some luxurious accommodations at Santa Maria Suites, where you can enjoy amenities like pillowtop beds, designer toiletries, and more. The 2 outdoor pools, poolside bar, and restaurant are just some of the popular amenities at this deluxe resort.
4.8/5 Exceptional! (1,001 reviews)
"Upscale and well maintained property with friendly and helpful staff"

Reviewed on Sep 20, 2022

The Southernmost House Hotel - Adults Only
3 out of 5
1400 Duval Street, Key West, FL, 33040
The price is $319 per night from Sep 25 to Sep 26
Treat yourself to a luxury stay at The Southernmost House Hotel - Adults Only, where you can enjoy amenities like pillowtop beds, designer toiletries, and more. Notable amenities include an outdoor pool, beach sun loungers, and a poolside bar.
4.6/5 Wonderful! (998 reviews)
"This was a fabulous location. Beautiful house. Great Staff throughout our stay. The pool was great!"

Reviewed on Sep 10, 2022

You could be seeing lower prices

You could be seeing lower prices

With member prices, you could save 10% or more right now on thousands of properties.
Oceans Edge Key West Resort, Hotel & Marina
4 out of 5
5950 Peninsular Avenue, Key West, FL, 33040
Fully refundableReserve now, pay when you stay
The price is $159 per night from Oct 2 to Oct 3
Pamper yourself with a luxury stay at Oceans Edge Key West Resort, Hotel & Marina, where you can enjoy amenities like Egyptian cotton sheets, plush bedding, and more. Deluxe amenities at this hotel include 6 outdoor pools, a marina, and free pool cabanas.
4.5/5 Wonderful! (1,806 reviews)
"First class all the way. Staff was helpful and friendly, restaurant was very good. Highly recommended."

Reviewed on Sep 17, 2022

The Marker Key West Harbor Resort
4 out of 5
200 William Street, Key West, FL, 33040
Fully refundableReserve now, pay when you stay
The price is $230 per night from Sep 26 to Sep 27
Be treated to a grand stay at The Marker Key West Harbor Resort, where you'll find deep soaking bathtubs and premium bedding. The 3 outdoor pools, poolside bar, and restaurant are just some of the popular amenities at this deluxe hotel.
4.3/5 Excellent! (1,003 reviews)
"Great place to stay. This is our second time to stay and next time we are in Key West we will stay there. We recommend it to all our friends."

Reviewed on Sep 23, 2022

Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL, 33040
The price is $119 per night from Sep 25 to Sep 26
Indulge yourself with upscale accommodations with a stay at Southwinds Motel, where you'll enjoy amenities like pillowtop beds and more. Deluxe amenities at this hotel include 3 outdoor pools, beach sun loungers, and a bar.
4.2/5 Excellent! (999 reviews)
"Love staying here while visiting Key West. The staff is always very friendly, clean rooms, and convenient to Duval st."

Reviewed on Sep 16, 2022

Fairfield Inn & Suites Key West at The Keys Collection
3.5 out of 5
3852 North Roosevelt Boulevard, Key West, FL, 33040
Fully refundableReserve now, pay when you stay
The price is $103 per night from Oct 2 to Oct 3
Be treated to a luxury stay at Fairfield Inn & Suites Key West at The Keys Collection, where you can enjoy amenities like pillowtop beds, premium channels, and more. Deluxe amenities at this hotel include an outdoor pool, a poolside bar, and a fitness center.
4.2/5 Excellent! (1,006 reviews)
"It was a nice stay"

Reviewed on Sep 21, 2022

Southernmost Beach Resort
4 out of 5
1319 Duval Street, Key West, FL, 33040
Fully refundableReserve now, pay when you stay
The price is $237 per night from Oct 3 to Oct 4
Southernmost Beach Resort is a Key West luxury 4-star beach property where you can pamper yourself with massage services, pillowtop beds, and more. The 2 poolside bars, 3 outdoor pools, and spa are just some of the popular amenities at this deluxe hotel.
4/5 Very Good! (1,855 reviews)
"We arrived early, and our room was ready, gotta love that ! Room had a great location and view, however, that makes it very popular place for everybody to hang out. Our neighbors above us were painfully loud, so we were able to change our room to a 3rd floor room. Cheryl W. was very helpful and accomodating ..."

Reviewed on Sep 21, 2022

Seashell Motel & Key West Hostel
1.5 out of 5
718 South Street, Key West, FL, 33340
Fully refundableReserve now, pay when you stay
The price is $67 per night from Sep 25 to Sep 26
Seashell Motel & Key West Hostel offers a luxury stay.
3.4/5 Good! (998 reviews)
"I liked very much"

Reviewed on Sep 21, 2022

Casa Marina Key West, Curio Collection by Hilton
5 out of 5
1500 Reynolds Street, Key West, FL, 33040
Fully refundableReserve now, pay when you stay
The price is $235 per night from Oct 3 to Oct 4
Casa Marina Key West, Curio Collection by Hilton is one of the Key West luxury 5-star beach properties where you can pamper yourself with massage services, designer toiletries, and more. Deluxe amenities at this resort include a private beach, a spa, and 2 outdoor pools.
3.3/5 (1,000 reviews)
"The architecture around the property was beautiful. The property is in real need of upgrades to the rooms (everything in the room needs upgraded). Other than that, everything else was great!"

Reviewed on Sep 11, 2022

Don't see what you're looking for?
See all available properties in Key West
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular luxurious hotels

Most upscale stays in Key West in 2022

Key West Luxury Hotels information

 

Luxury Hotels in Key West

64

Highest price $319
Cheapest price $67
Number of guest reviews 11034
Total number of hotels in Key West 2301

 

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Key West?

Fly into Key West Intl. Airport (EYW) Airport and then pamper yourself by staying at one of 10 Key West luxury hotels. Known for its ocean views and sunsets, Key West also has some interesting things to see and do including Duval Street, so you may want to take in the local sights during your visit.

What's the best luxury place to stay in Key West?

Casa Marina Key West, Curio Collection by Hilton is a 5-star resort with a private beach and 3 restaurants, and it's a popular choice for Expedia travelers looking for a pampering stay.

How many luxury hotels will I be able to find in Key West?

Lie in the lap of luxury during your getaway to Key West in one of Expedia's 10 luxury hotels.

When can I expect good weather in Key West?

Planning for the weather is a good way to make your trip to Key West relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 84°F, while the coldest months are January and December with an average of 71°F. Average annual precipitation for Key West is 40 inches.

What's there to see and do in Key West?

Experience Key West with a stop at Duval Street, Ernest Hemingway Home and Museum, and Harry S. Truman Little White House. If you have spare time during your trip, you might want to make a stop at Mallory Square and Key West Butterfly and Nature Conservatory.

Recent reviews of Key West hotels
expedia verified reviews

Plan your trip in a snap on the app

From home or hammock, organize your entire escape and explore app offers

Text yourself a download link for easy access

Get a link to download the app in the Apple App Store or Google Play Store. 1 message per request. Message and data rates may apply. Text HELP for help or STOP to unsubscribe. Review the App Download SMS terms at www.expedia.com/app. For privacy, please go to www.expedia.com/lp/lg-privacypolicy.
QR code