Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Knoxville Independent Hotels

See all 147 Hotels in Knoxville
Red Roof Inn Knoxville Central - Papermill Road

Red Roof Inn Knoxville Central - Papermill Road

1315 Kirby Rd, Knoxville
3.0 out of 5.0
3.3 out of 5 (1,948 reviews)
Nice hotel close to the interstate. Clean room. Good breakfast. Nice staff. Decent price for room. - 

$52

$52
La Quinta Inn & Suites Knoxville Central Papermill

La Quinta Inn & Suites Knoxville Central Papermill

1317 Kirby Rd, Knoxville
2.5 out of 5.0
4.4 out of 5 (508 reviews)
Modern and clean hotel We drive through Knoxville on trips so we only stay at the hotel overnight but it’s always an easy … - 

$85

$85
Clarion Inn & Suites Near Downtown

Clarion Inn & Suites Near Downtown

5335 Central Ave Pike, Knoxville
2.5 out of 5.0
4.0 out of 5 (104 reviews)
Awesome staff! The staff is delightful. There should be more than 1 person working the breakfast room. Bathroom sh … - 

$79

$79
Four Points by Sheraton Knoxville Cumberland House Hotel

Four Points by Sheraton Knoxville Cumberland House Hotel

1109 White Ave, Knoxville
3.0 out of 5.0
4.4 out of 5 (660 reviews)
Met our needs We needed a hotel to park at that was a close walk to the strip and Neyland. This hotel met our nee … - 

$99

$99
Motel 6 Knoxville

Motel 6 Knoxville

258 Harry Lane Blvd, Knoxville
2.0 out of 5.0
3.3 out of 5 (826 reviews)
Quick and easy check in. Clean and quiet room. Perfect for just a single night for passing through. - 

$45

$45
Red Roof Inn Knoxville West – Cedar Bluff

Red Roof Inn Knoxville West – Cedar Bluff

208 Market Pl Blvd, Knoxville
2.0 out of 5.0
3.5 out of 5 (830 reviews)
Glad we chose this hotel From the moment we checked in until we left our experience at Red Roof Inn was wonderful. Friendly … - 

$53

$53
Red Roof Inn Knoxville North - Merchants Drive

Red Roof Inn Knoxville North - Merchants Drive

5334 Central Avenue Pike, Knoxville
2.0 out of 5.0
3.1 out of 5 (418 reviews)
Good place to stay for UTgame given the price comparisons - 

$53

$53
Country Inn & Suites By Carlson, Knoxville At Cedar Bluff

Country Inn & Suites By Carlson, Knoxville At Cedar Bluff

9137 Cross Park Drive, Knoxville
2.5 out of 5.0
4.5 out of 5 (995 reviews)
Great experience, except for the thermostat Everything was A+ except for not being able to change the room temperature on the thermostat. My wi … - 

$89

$89
Country Inn & Suites By Carlson, Knoxville Airport, TN

Country Inn & Suites By Carlson, Knoxville Airport, TN

162 Cusick Rd, Alcoa
2.5 out of 5.0
4.0 out of 5 (973 reviews)
Upgrade from worse I relocated from another local hotel to this one, due to an insect infestation. The difference allo … - 

$65

$65
M Star Hotel Alcoa

M Star Hotel Alcoa

2962 Alcoa Hwy, Alcoa
2.0 out of 5.0
2.6 out of 5 (529 reviews)
Nice hotel close to the airport. It was a nice, clean room with a good radio to listen to the football game preshow before heading d … - 

$40

$40
Crowne Plaza Hotel Knoxville Downtown University

Crowne Plaza Hotel Knoxville Downtown University

401 W Summit Hill Dr, Knoxville
3.5 out of 5.0
4.4 out of 5 (775 reviews)
Here for a conference. Staff was Awesome! Clean, nice room! Perfect! - 

$108

$108
Holiday Inn Knoxville Downtown

Holiday Inn Knoxville Downtown

525 Henley St, Knoxville
3.5 out of 5.0
4.3 out of 5 (945 reviews)
Nice hotel for football weekend One female staff member at check in counter wasn’t the friendliest. Didn’t get Our Room cleaned til … - 

$92

$92
Extended Stay America - Knoxville - Cedar Bluff

Extended Stay America - Knoxville - Cedar Bluff

214 Langley Pl, Knoxville
2.5 out of 5.0
3.6 out of 5 (268 reviews)
Peace quiet relaxing excellent Staff excellent room clean grwat value beautiful place plenty of food places - 

$58

$58
Country Inn & Suites By Carlson, Knoxville West, TN

Country Inn & Suites By Carlson, Knoxville West, TN

805 N Campbell Station Rd, Knoxville
2.5 out of 5.0
4.1 out of 5 (616 reviews)
Snowbird travel Excellent hotel for the price, midway point to/from SW Florida to/from Ontario, Canada. - 

$71

$71
La Quinta Inn & Suites Knoxville Airport

La Quinta Inn & Suites Knoxville Airport

126 Cusick Road, Alcoa
2.5 out of 5.0
4.3 out of 5 (674 reviews)
Good value hotel La Quinta Knoxville is right next to the airport, very convenient to UT and downtown Knoxville via … - 

$75

$75
La Quinta Inn & Suites Knoxville North I-75

La Quinta Inn & Suites Knoxville North I-75

7534 Conner Rd, Powell
3.0 out of 5.0
4.0 out of 5 (156 reviews)
Convenient to I75 Clean and safe for holiday travels. Price is good. - 

$76

$76
Motel 6 Knoxville North

Motel 6 Knoxville North

5640 Merchants Center Blvd, Knoxville
2.0 out of 5.0
2.4 out of 5 (160 reviews)
Nice hotel close to where I wanted to be Enjoy the room but it would have been nice to have a refrigerator and a microwave - 

$40

$40
Travelodge Knoxville East

Travelodge Knoxville East

7471 Crosswood Blvd, Knoxville
2.5 out of 5.0
2.5 out of 5 (39 reviews)
Beautiful hotel A place to be, the hotel is awesome with a beautiful environment. - 

$40

$40
Knoxville Marriott

Knoxville Marriott

501 East Hill Avenue, Knoxville
3.5 out of 5.0
4.1 out of 5 (351 reviews)
Completely acceptable You're not gonna be blown away, but it's completely acceptable. The toilet in the room above me had … - 

$119

$119
WoodSpring Suites Knoxville Airport

WoodSpring Suites Knoxville Airport

4412 Singleton Station Rd, Louisville
2.5 out of 5.0
3.6 out of 5 (69 reviews)
great room, great price Great motel for a short stay before flying in or out of Knoxville TN. Highly recommend this place. - 

$56

$56
Map

Recently booked Knoxville hotels

Microtel Inn by Wyndham Knoxville
2.0 out of 5.0
Last booking: 2 hours ago
Holiday Inn Express & Suites Lenoir Cty
2.5 out of 5.0
Last booking: 5 hours ago
Quality Inn And Suites Knoxville
2.5 out of 5.0
Last booking: 5 hours ago
Clarion Inn & Suites West Knoxville
2.5 out of 5.0
Last booking: 5 hours ago
Hilton Knoxville
3.5 out of 5.0
Last booking: 6 hours ago
La Quinta Inn & Suites Knoxville North I-75
3.0 out of 5.0
Last booking: 6 hours ago
Hampton Inn & Suites-Knoxville / North I-75
2.5 out of 5.0
Last booking: 6 hours ago
Motel 6 Knoxville
2.0 out of 5.0
Last booking: 7 hours ago
Super 8 Knoxville Downtown Area
2.0 out of 5.0
Last booking: 7 hours ago

Independent Knoxville Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Knoxville, Tennessee. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Knoxville hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Knoxville Independent locations may even offer extra little benefits and discounts for frequent travelers.