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Featured Lake City Luxury Hotels

See all 121 Hotels in Lake City
Palms Garden Inn

Palms Garden Inn

14113 S. US Hwy 441, Lake City
2.5 out of 5.0
3.5 out of 5 (156 reviews)
Comfortable and convenient. Right off the interstate. Easy access with clean and comfortable rooms. Full of amenities.
  Feb 13, 2018

$55

$55
Americas Best Value Inn - Lake City

Americas Best Value Inn - Lake City

3835 West US Highway 90, Lake City
2.0 out of 5.0
3.5 out of 5 (427 reviews)
Basic accommodation along the wayNothing fancy, but clean and quiete enough to feel ok
  Aug 11, 2014

$64

$64
Driftwood Inn

Driftwood Inn

2764 W US Hwy 90, Lake City
2.5 out of 5.0
3.5 out of 5 (207 reviews)
Nice inexpensive hotelThis was a nice family hotel, well maintained, clean. Everything worked properly. Nothing fancy but if you are looking for a clean place to stay without spending a lot of money, this hotel is a good choice.
 Scott Dec 20, 2017

$55

$55
Econo Lodge Lake City

Econo Lodge Lake City

178 Sw Florida Gateway Dr, Lake City
2.5 out of 5.0
3.1 out of 5 (145 reviews)
Great room, great staff, load interstateWe only stayed one night in the middle of a road trip, and the room was very clean, beds very comfortable, staff very pleasant but if you stay on the side near the interstate, you will hear the noise all night.The continental breakfast consisted on cereal, milk and packaged muffins. Nothing fancy, ...
  Jul 3, 2015

$62

$62
Ramada Limited Lake City

Ramada Limited Lake City

3340 W US HWY 90, Lake City
2.0 out of 5.0
2.6 out of 5 (427 reviews)
On the way to Disney WorldVery convenient location. Ok if you are just looking for a place to sleep. Smelled bad, old hotel, needs renovations... or at least fresh paint. Nothing fancy, little or no amenities.
  May 24, 2015

$58

$58
Comfort Suites Lake City

Comfort Suites Lake City

3690 W Us Highway 90, Lake City
2.5 out of 5.0
4.7 out of 5 (540 reviews)
Pleasant stay.We had a very pleasant stay on our way to Disney. Would highly recommend.
  Feb 18, 2018

$107

$107
Days Inn Lake City I-10

Days Inn Lake City I-10

3430 N Us Highway 441, Lake City
2.0 out of 5.0
3.4 out of 5 (535 reviews)
As expected Older hotel off the interstate. As expected. Room was clean.
  Jan 28, 2018

$56

$56
Super 8 Lake City

Super 8 Lake City

3954 SW State Road 47, Lake City
2.5 out of 5.0
3.1 out of 5 (287 reviews)
This is the 3rd time I have stayed at this motelThis motel is clean and well kept. Nothing fancy but a nice place to stay. This is the third time I have stayed here and each time has been a good experience.
 Jean Nov 30, 2013

$85

$85
Rodeway Inn Lake City

Rodeway Inn Lake City

205 Sw Commerce Dr, Lake City
3.3 out of 5 (148 reviews)
Served its purposeWe were only passing through and needed a place to sleep and shower. This place met our needs. It's by no means luxurious but the room was comfortable and kept clean. The A/C was off when we arrived and the room took a while to cool down. You get what you pay for. I would definitely stay again especially ...
 tourist Jan 4, 2014

$52

$52

Recently booked Luxury Hotels in Lake City

Rodeway Inn Lake City
0.0 out of 5.0
Last booking: 6 hours ago
Palms Garden Inn
2.5 out of 5.0
Last booking: 8 hours ago
Country Inn & Suites by Radisson, Lake City, FL
3.0 out of 5.0
Last booking: 10 hours ago
Holiday Inn & Suites Lake City
3.5 out of 5.0
Last booking: 12 hours ago
Comfort Suites Lake City
2.5 out of 5.0
Last booking: 13 hours ago
Fairfield Inn & Suites Lake City
3.0 out of 5.0
Last booking: 14 hours ago
Baymont Inn & Suites Lake City
3.0 out of 5.0
Last booking: 16 hours ago
Ramada Limited Lake City
2.0 out of 5.0
Last booking: 18 hours ago
Super 8 Lake City
2.5 out of 5.0
Last booking: 37 hours ago

A weekend away keeps your stress at bay, so plan a vacation in Lake City and get ready to relax. Fascinating sites, divine eats, and the most breathtaking photo opportunities: these are just a few of the reasons to take a vacation to Lake City. You'll devour spectacular cuisine, get in line to check out the coolest attractions, and enjoy the most sought-after shows. Where else would you stay but in a luxury accommodation? Anything less than the best is for the birds, so reserve your upscale hotel in Lake City on Expedia.com today and start your trip off on the right (well-dressed) foot.

5-Star Vacations in Lake City

It turns out plenty of folks have decided to have set down roots -- how is that for proof that Lake City is full of an exciting array of activities? Whether you’re looking to spend your vacation dining on haute cuisine or browsing art galleries in Lake City, you'll never be disappointed. Lake City is full of dreamy hotels on top of appealing attractions, so it's no mystery why travelers often return. Book well in advance to get a room with a view!

An upscale vacation calls for facials, culture, and activities from your bucket list. When you save big by booking on Expedia.com, the world is your oyster. Thanks to our hotel deals, you'll still have money in your budget for the most fun and free-spirited adventures. After an eventful day of exploring the city, your luxury accommodations will welcome you back to out-of-this-world amenities. Don't fall asleep before enjoying the view off your balcony or asking the concierge for advice on tomorrow's plans. The luxury rooms and suites in Lake City will soothe you into a state of bliss in no time.

Luxury Lake City Hotels

It's that time; you're prepared to get swept away in Lake City, and Expedia.com is here to save the day. Browse the abundance of ratings and reviews on incredible hotels and find the perfect vacation rental. 5-Star hotels treat you right, offering things like high end bath amenities and private fireplaces. Many luxe accommodations in Lake City even feature gigantic suites, and it's not uncommon to enjoy incredible in-house dining in your hotel. Use our mobile booking app to find and book a fabulous 5-star hotel in Lake City, and before you know it you'll be getting pampered in paradise!