Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Lancaster Luxury Hotels

See all 294 Hotels in Lancaster
Motel 6 Lancaster

Motel 6 Lancaster

43540 17th St W, Lancaster
    2.0 out of 5.0
     
     
    3.2 out of 5 (147 reviews)
    Unfortunately, Expedia did NOT give me the least expensive hotel as promised. One block away was a hotel some $10-15 dollars less expensive. Thanks anyway for the contact. P.O.R.
    Apr 16, 2018

    Motel 6 Lancaster$66

    Motel 6 Lancaster$66
    Americas Best Value Inn and Suites Lancaster

    Americas Best Value Inn and Suites Lancaster

    44131 Sierra Highway, Lancaster
      2.0 out of 5.0
       
       
      3.7 out of 5 (276 reviews)
      Lancaster CANo Kleenex anymore - bad decision. At check in room was missing wash cloths, ice bucket and extra toilet paper. Staff got them too us immediately, but they should have been in the room without asking. Staff was exceptionally nice and helpful.
      Apr 17, 2018

      Americas Best Value Inn and Suites Lancaster$67

      Americas Best Value Inn and Suites Lancaster$67
      Knights Inn Palmdale Lancaster Area

      Knights Inn Palmdale Lancaster Area

      130 E Palmdale Blvd, Palmdale
        1.5 out of 5.0
         
         
        3.1 out of 5 (849 reviews)
        It's a really clean Place good service they have breakfast in the morning . all the stores are close by restaurants are close by and that's a good thing for me.
        Apr 9, 2018

        Knights Inn Palmdale Lancaster Area$60

        Knights Inn Palmdale Lancaster Area$60
        Best Western Plus John Jay Inn & Suites

        Best Western Plus John Jay Inn & Suites

        600 W Palmdale Blvd, Palmdale
          2.5 out of 5.0
           
           
          4.2 out of 5 (542 reviews)
          Nice hotel, little pricey.It was a very clean room, I had a nice stay. Big thanks to the front desk. I had driven a l Iong way to get there and I was a bit too early for check in. They found a room ready...thank you so much! I was so tired.
          Apr 18, 2018

          Best Western Plus John Jay Inn & Suites$89

          Best Western Plus John Jay Inn & Suites$89
          Oxford Inn & Suites Lancaster

          Oxford Inn & Suites Lancaster

          1651 W Avenue K, Lancaster
            3.0 out of 5.0
             
             
            4.3 out of 5 (937 reviews)
            Getting to the hotel was very easy, checking in was fast and the stuff was really friendly...
            Apr 16, 2018

            Oxford Inn & Suites Lancaster$95

            Oxford Inn & Suites Lancaster$95
            Ramada Palmdale

            Ramada Palmdale

            300 W Palmdale Blvd, Palmdale
              2.5 out of 5.0
               
               
              3.3 out of 5 (637 reviews)
              Little things matterGreat front desk staff, but would have preferred not to have to ask them for towels, shampoo, soap. Room set up needs more care Convenient location and breakfast a big plus
              Apr 17, 2018

              Ramada Palmdale$64

              Ramada Palmdale$64
              Hilton Garden Inn Palmdale

              Hilton Garden Inn Palmdale

              1309 W Rancho Vista Blvd, Palmdale
                3.0 out of 5.0
                 
                 
                4.5 out of 5 (418 reviews)
                Great stay in PalmdaleWe were in town for a family event and needed a hotel close to the freeway. This location is odd because its at the end of a busy mall, however its perfect for quick access to Lancaster and Quartz Hill. The hotel itself is very modern, clean and the reception help was nice. There is free coffee and ...
                Apr 9, 2018

                Hilton Garden Inn Palmdale$139

                Hilton Garden Inn Palmdale$139
                Embassy Suites Palmdale

                Embassy Suites Palmdale

                39375 5th St W, Palmdale
                  3.5 out of 5.0
                   
                   
                  4.6 out of 5 (766 reviews)
                  Close to shopping and restraunts! Staying with teenagers can get crazy. Thankfully there was a shopping center within walking distance so the teens could hang out and parents could relax.
                  Apr 16, 2018

                  Embassy Suites Palmdale$148

                  Embassy Suites Palmdale$148
                  Holiday Inn Express Lancaster

                  Holiday Inn Express Lancaster

                  43719 17th St W, Lancaster
                    2.5 out of 5.0
                     
                     
                    4.3 out of 5 (250 reviews)
                    Staff was so helpful and friendly !!!Hotel staff amazing from the beginning ! Family friendly hotel !
                    Feb 12, 2018

                    Holiday Inn Express Lancaster$103

                    Holiday Inn Express Lancaster$103
                    Hampton Inn Suites Palmdale

                    Hampton Inn Suites Palmdale

                    39428 Trade Center Dr, Palmdale
                      2.5 out of 5.0
                       
                       
                      4.4 out of 5 (415 reviews)
                      Very good. Easy access. Lots of restaurants close.
                      Apr 19, 2018

                      Hampton Inn Suites Palmdale$93

                      Hampton Inn Suites Palmdale$93

                      Recently booked Luxury Hotels in Lancaster

                      Motel 6 Palmdale
                      2.0 out of 5.0
                      Last booking: 1 hour ago
                      Ramada Palmdale
                      2.5 out of 5.0
                      Last booking: 1 hour ago
                      Best Western Plus John Jay Inn & Suites
                      2.5 out of 5.0
                      Last booking: 4 hours ago
                      Hampton Inn Suites Palmdale
                      2.5 out of 5.0
                      Last booking: 5 hours ago
                      Holiday Inn Palmdale-Lancaster
                      3.0 out of 5.0
                      Last booking: 7 hours ago
                      Oxford Inn & Suites Lancaster
                      3.0 out of 5.0
                      Last booking: 7 hours ago
                      Hilton Garden Inn Palmdale
                      3.0 out of 5.0
                      Last booking: 8 hours ago
                      E-Z 8 Motel Lancaster
                      2.5 out of 5.0
                      Last booking: 8 hours ago
                      Best Western Plus Desert Poppy Inn
                      3.0 out of 5.0
                      Last booking: 10 hours ago

                      When you'll take your luxury hotel with a side of thrilling city attractions, look no further than Lancaster. As one of the most interesting destinations for adventurers who want to soak up the energy of a big city, Lancaster always impresses. Intriguing monuments, divine eats, and the most coveted photo opportunities: these are just some of the reasons to take a vacation to Lancaster. You'll devour spectacular eats, get in line to check out the coolest attractions, and grab tickets to the most popular performances. Where else would you stay but a luxury accommodation? Sampling the finer things in life is just your speed, so reserve your luxury hotel in Lancaster on Expedia.com today and start your vacation off on the right (well-dressed) foot.

                      5-Star Vacations in Lancaster

                      It turns out 161,103 people love Lancaster enough to call it home -- how is that for proof that Lancaster is full of wonderful things to do? Whether you’re looking to spend your vacation dining on haute cuisine or browsing art galleries in Lancaster, you'll never be disappointed. Lancaster is full of great hotels on top of appealing attractions, so it's no surprise that travelers often return. Book early to ensure you snag a room!

                      Any 5-star getaway calls for pedicures, culture, and activities from your bucket list. When you book your trip on Expedia.com, it's all at your fingertips. Thanks to our hotel deals, your bucket list budget will still be intact. After a day of exploring the city, your luxury accommodation awaits. Don't fall asleep before enjoying the view off your balcony or sipping on a glass of fine wine. The luxury hotels in Lancaster will render you into a state of serenity before you know it.

                      Luxury Lancaster Hotels

                      There's no better time than right now to book a hotel in Lancaster, and Expedia.com is here to save the day. Browse the wealth of ratings and reviews on more than a dozen hotels and then book your ideal room in minutes. Luxury accommodations offer amenities like elegant suites and VIP services. Some of the city's luxury accommodations even feature impeccable penthouses, while others offer pampering spa treatments. Use our easy booking widget to find and book the ideal 5-star hotel in Lancaster, and before you know it you'll be feeling blissful in paradise!