Find all hotels by Motel 6 in Little Italy, CA from $70
Check prices for these dates
Our top choices for Little Italy Motel 6
Motel 6 San Ysidro, CA - San Diego - Border
San Ysidro
7.0 out of 10, Good, (1470)
"exceptional "
Clarissa
$67 nightly
The price is $76
Dec 14 - Dec 15
Total with taxes and fees
Motel 6 El Cajon, CA - San Diego
El Cajon
7.4 out of 10, Good, (1453)
"My stay here was pretty cool"
Rana
$69 nightly
The price is $77
Dec 10 - Dec 11
Total with taxes and fees
Motel 6 Chula Vista, CA - San Diego
Chula Vista
6.0 out of 10, (1787)
"Very nice service "
Maria
$66 nightly
The price is $74
Dec 10 - Dec 11
Total with taxes and fees
Motel 6 San Diego, CA - Downtown
Downtown San Diego
6.2 out of 10, (1242)
"Great space and ease of access"
Darren
$62 nightly
The price is $72
Dec 10 - Dec 11
Total with taxes and fees
Motel 6 San Diego, CA - Hotel Circle - Mission Valley
Mission Valley
6.8 out of 10, (1479)
"Great location but the hotel needs a deep cleaning. "
Michael
$73 nightly
The price is $84
Dec 16 - Dec 17
Total with taxes and fees
Motel 6 San Diego Airport - Harbor
Downtown San Diego
7.0 out of 10, Good, (1006)
"Had a great relaxful evening. Staff was awesome and helpful."
Joel
$62 nightly
The price is $70
Dec 10 - Dec 11
Total with taxes and fees
Motel 6 San Diego, CA - Southbay
Nestor
7.4 out of 10, Good, (1001)
"Nice friendly staff and manager clean rooms "
Christopher
$72 nightly
The price is $81
Dec 14 - Dec 15
Total with taxes and fees
Motel 6 San Diego, CA - North
Clairemont
6.8 out of 10, (1004)
"Great stay, especially for the price. "
Jake
$83 nightly
The price is $94
Dec 31 - Jan 1, 2026
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Little Italy Hotel Reviews
Hampton Inn San Diego-Downtown
10/10 Excellent
Find out more about Little Italy
Visit Little Italy
Little Italy is a vibrant neighborhood known for its top museums and major shopping area. Experience the best of Little Italy with a visit to Waterfront Park and Maritime Museum of San Diego during your trip. You'll find 53 hotels and other accommodations in Little Italy to choose from, making this an ideal home base for exploring the greater San Diego area.
Best Places to Stay in Little Italy
Our guests mention these as some of their favorite Little Italy lodging choices:
- Homewood Suites by Hilton San Diego Downtown/Bayside: 3.5-star hotel with free breakfast, a restaurant, and an outdoor pool, 14-minute walk from Port of San Diego. Our guests enjoy the hotel's spacious rooms and central location.
- Hilton Garden Inn San Diego Downtown/Bayside, CA: 3.5-star hotel with a restaurant, an outdoor pool, and a fitness center, 14-minute walk from Port of San Diego. Expedia travelers like this hotel's comfortable rooms and beach locale.
- Residence Inn by Marriott San Diego Downtown: 3-star hotel with free breakfast, an outdoor pool, and a 24-hour fitness center, steps from Waterfront Park. Our guests rate this hotel highly for its spacious rooms and walkable location.
What to Do in This San Diego Neighborhood
You might want to spend some time browsing the exhibits at Firehouse Museum, Maritime Museum of San Diego, or Museum of Contemporary Art San Diego during your stay in Little Italy. A visit to Waterfront Park is also worth the trip while you're discovering the neighborhood.
Favorite places to visit in the surrounding Little Italy area include B Street Cruise Ship Terminal, Port of San Diego, and USS Midway Museum. While you're out sightseeing, Seaport Village and Petco Park are a couple of additional sights to visit in San Diego.
Getting Around Little Italy and the Greater San Diego Area
Ready to get out and explore the city? County Center - Little Italy Station is the closest metro station. Learn about your options for water transportation at the port.
Explore a world of travel with Expedia
- San Diego County Hotels
- San Diego Hotels
- Cheap Hotels in San Diego County
- Hotels near Downtown San Diego
- Beach Hotels in San Diego County
- Hotels near Gaslamp Quarter
- Cheap Hotels in San Diego
- Hotels near San Diego Intl.
- All-inclusive Resorts in San Diego
- Hotels with Free Airport Shuttle in San Diego
- Extended Stay Hotels in San Diego
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Oceanfront Hotels in San Diego County
- Marriott Hotels & Resorts in San Diego
- Hotels near Petco Park
- Pet-friendly Hotels in San Diego County
- Hotels near Waterfront Park
- Hotels with Suites in San Diego
- Vacation Homes in County Center - Little Italy Station
- Hotels near County Center - Little Italy Station
- Hotels near Harborview
- Hotels near Our Lady of the Rosary Catholic Church
- Hotels near Firehouse Museum
- Family Hotels in San Diego County
- Casino Hotels in San Diego County
- Motels in San Diego County
- Hotels near Maritime Museum of San Diego
- Hilton Hotels in San Diego
- Best Western Hotels in San Diego
- Bartell Hotels in San Diego
- Hotels near Star of India
- Hotels near B Street Cruise Ship Terminal
- Red Roof Inn Hotels in San Diego
- Hyatt Hotels in San Diego
- Occidental Hotels in San Diego
- OYO Rooms Hotels in San Diego
- Accor Hotels in San Diego
- Wyndham Hotels in San Diego
- Club Quarters Hotels in San Diego
- Starwood Capital Hotels in San Diego
- Fiesta Americana Hotels & Resorts in San Diego
- Noble House Hotels in San Diego
- Motel 6 Hotels in San Diego
- Kimpton Hotels in Downtown San Diego
- Vagabond Inn Hotels in San Diego
- Wyndham Extra Holidays Hotels in San Diego
- Four Seasons Hotels in San Diego
- Wynn Resorts in San Diego
- Independent Hotels in San Diego
- Highgate Independent Hotels in San Diego
- Relais & Chateaux Hotels in San Diego
- La Quinta Inn & Suites Hotels in San Diego
- Kimpton Hotels in San Diego
- Extended Stay America Hotels in San Diego
- Oakwood Hotels in San Diego
- Hotels with Kitchenettes in San Diego
- All-inclusive Resorts in San Diego County
- Beach Hotels in San Diego
- Hostels in San Diego
- Best Western Hotels in Downtown San Diego
- Marriott Hotels & Resorts in Downtown San Diego
- Flights to San Diego
- Flights from San Francisco (SFO) to San Diego (SAN)
- Flights from Seattle (SEA) to San Diego (SAN)
- Flights from Phoenix (PHX) to San Diego (SAN)
- Flights from New York (JFK) to San Diego (SAN)
- Flights from Las Vegas (LAS) to San Diego (SAN)
- Flights from Chicago (ORD) to San Diego (SAN)
- Flights from Dallas (DFW) to San Diego (SAN)
- Flights from San Jose (SJC) to San Diego (SAN)
- Flights from Los Angeles (LAX) to San Diego (SAN)
- Flights from Denver (DEN) to San Diego (SAN)
- Flights from San Diego Intl.
- Flights from Portland (PDX) to San Diego (SAN)
- Flights from Boston (BOS) to San Diego (SAN)
- Flights from Sacramento (SMF) to San Diego (SAN)
- Flights from Houston (IAH) to San Diego (SAN)
- Flights from Salt Lake City (SLC) to San Diego (SAN)
- Flights from Fresno (FAT) to San Diego (SAN)
- Flights from Minneapolis (MSP) to San Diego (SAN)
- Flights from Atlanta (ATL) to San Diego (SAN)
- Flights from Philadelphia (PHL) to San Diego (SAN)
- Flights to San Diego County
- Flights from Detroit (DTW) to San Diego (SAN)
- Flights from Washington (IAD) to San Diego (SAN)