Beginning of main content

Los Cabos Hotel Rooms at the One&Only Resorts

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Los Cabos Hotels

Search Flight + Hotel

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Los Cabos One&Only Resorts Hotels

See all 325 Hotels in Los Cabos
One&Only Palmilla Resort

One&Only Palmilla Resort

Km 7.5 Carretera Transpeninsular, San Jose Del Cabo
5.0 out of 5.0
4.9 out of 5 (136 reviews)
It was amazing. The hotel was always clean! The landscape was beautiful, the staff always greeted us in Spanish which really made us feel like … - 

$585

$585
Map

Recently booked Los Cabos hotels

Cabo Inn Hotel
2.0 out of 5.0
Last booking: 18 minutes ago
Sandos Finisterra Los Cabos All Inclusive Resort
4.0 out of 5.0
Last booking: 31 minutes ago
Cabo Vista Hotel - Adults only
3.0 out of 5.0
Last booking: 46 minutes ago
Solmar Resort
3.5 out of 5.0
Last booking: 1 hour ago
Breathless Cabo San Lucas - All Inclusive - Adults Only
4.5 out of 5.0
Last booking: 1 hour ago
Hotel Santa Fe by Villa Group
2.5 out of 5.0
Last booking: 1 hour ago
The Cape - A Thompson Hotel
5.0 out of 5.0
Last booking: 1 hour ago
Grand Fiesta Americana Los Cabos All Inclusive Golf & Spa
4.5 out of 5.0
Last booking: 2 hours ago
Pueblo Bonito Los Cabos Blanco - All Inclusive
4.0 out of 5.0
Last booking: 3 hours ago

One&Only Resorts Los Cabos Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of One&Only Resorts hotels in Los Cabos, Baja California Sur. Known for well-appointed rooms and friendly, personalized service, each of the top One&Only Resorts Los Cabos hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Los Cabos One&Only Resorts locations may even offer extra little benefits and discounts for frequent travelers.