Photo by Lisa Travelfeet

Find Resorts & Hotels with Spas in Los Osos, CA

Start date: Check-in selected.
To Date
End date: Check-out

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Los Osos Resorts & Hotels with Spas

Tonight
Dec 2 - Dec 3
Tomorrow
Dec 3 - Dec 4
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Top Los Osos Resorts & Hotels with Spas

Outdoor pool
Sea Pines Resort

Sea Pines Resort

3.0 star property
Los Osos
8.2 out of 10, Very Good, (410)
"Nice staff."
United States
Ann
$179 nightly
The price is $201
Dec 11 - Dec 12
Total with taxes and fees
Sea Pines Resort
Property entrance
Avila Village Inn

Avila Village Inn

3.5 star property
Avila Beach
9.2 out of 10, Wonderful, (1000)
"The property and rooms were beautiful! We really enjoyed our weekend here and are planning to stay again!"
United States
Cathy
$155 nightly
The price is $175
Dec 3 - Dec 4
Total with taxes and fees
Avila Village Inn
Caveman | Bathroom | Shower, hair dryer, bathrobes, towels
Madonna Inn

Madonna Inn

3.5 star property
San Luis Obispo
9.2 out of 10, Wonderful, (1312)
"Fun place"
United States
Kyle
$167 nightly
The price is $190
Dec 9 - Dec 10
Total with taxes and fees
Madonna Inn
Restaurant
The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection

2.5 star property
Arroyo Grande
9.6 out of 10, Exceptional, (1016)
"Room was nice as well as breakfast and happy hour."
United States
Leon
$134 nightly
The price is $153
Dec 3 - Dec 4
Total with taxes and fees
The Agrarian Hotel, BW Signature Collection
Exterior
Cayucos Sunset Inn B&B

Cayucos Sunset Inn B&B

3.5 star property
Cayucos
9.8 out of 10, Exceptional, (194)
"Great place to stay"
United States
Jason
$175 nightly
The price is $196
Dec 4 - Dec 5
Total with taxes and fees
Cayucos Sunset Inn B&B
Reception
HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection

4.0 star property
Downtown San Luis Obispo
9.2 out of 10, Wonderful, (466)
"We had a great stay"
United States
ADALBERT
$250 nightly
The price is $284
Dec 7 - Dec 8
Total with taxes and fees
HOTEL CERRO, Autograph Collection
Property grounds
Avila La Fonda Hotel

Avila La Fonda Hotel

4.0 star property
Avila Beach
9.6 out of 10, Exceptional, (1000)
"Very nice hotel. Great for and rest and relaxation kind of vacation"
United States
Princess
$192 nightly
The price is $217
Dec 8 - Dec 9
Total with taxes and fees
Avila La Fonda Hotel
Morro Suite | Living area | 55-inch flat-screen TV with cable channels, TV
Hotel San Luis Obispo

Hotel San Luis Obispo

4.5 star property
Downtown San Luis Obispo
9.4 out of 10, Exceptional, (543)
"Beautiful room and nice rooftop bar!"
United States
Chizuru
$278 nightly
The price is $316
Dec 7 - Dec 8
Total with taxes and fees
Hotel San Luis Obispo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.
Book now

Find out more about Los Osos

Top Los Osos attractions for a relaxing vacation

Los Osos, California, offers a serene coastal retreat perfect for travelers who appreciate the tranquility of spa hotels. Begin your journey at Montana de Oro State Park, where scenic hiking trails lead to breathtaking ocean views, ideal for unwinding before your spa day. Next, immerse yourself in the natural beauty of Morro Bay, where kayaking through the calm waters allows for close encounters with sea otters and other wildlife, enhancing your connection to nature. Explore the charming local shops and eateries in downtown Los Osos, which provide a taste of the community's welcoming vibe. For a unique experience, visit the Elfin Forest, a delightful coastal woodland with boardwalk trails that offer gentle strolls amid stunning flora, perfect for relaxation. Finally, after a day of exploration, indulge in rejuvenating treatments at one of the area's upscale hotels with spa facilities, such as the luxurious accommodations that prioritize personalized service and high-quality amenities. Staying in this peaceful town allows you to easily traverse its natural wonders while enjoying the pampering you deserve.

Find the best hotels & resorts with spas in Los Osos

For those seeking a rejuvenating escape in Los Osos, these hotels offer exceptional spa amenities that promise relaxation and tranquility during your stay.

Sea Pines Resort

  • Why it's great for tailored spa getaway: Sea Pines Resort is a haven for travelers looking to indulge in luxurious spa treatments. With an excellent guest review rating of 8.2, this resort features a full-service spa offering a variety of treatments, including deep tissue and hot stone massages. Guests can also enjoy unique spa experiences in couples treatment rooms, making it a perfect retreat for couples seeking relaxation and rejuvenation.
  • Other amenities: Beyond the spa, guests can unwind at the onsite hot springs or take a dip in the hot tub. The resort also features picturesque golf views, with an onsite golf course and lessons available for enthusiasts. For those seeking adventure, nearby activities include windsurfing, kayaking, and hiking. Additional conveniences include room service, a terrace for relaxation, and daily housekeeping to ensure a comfortable stay.
  • Nearby attractions: Montaña de Oro State Park - 0.27 miles, Morro Dunes Natural Preserve - 0.4 miles, Morro Coast Audubon Society Sweet Springs Nature Preserve - 1.15 miles

Top Los Osos Hotel Reviews

Hilton Garden Inn San Luis Obispo/Pismo Beach

Hilton Garden Inn San Luis Obispo/Pismo Beach

10/10 Excellent
"Rooms were spacious "
LEONA 1-night trip
Posted 23 hours ago
Hilton Garden Inn San Luis Obispo/Pismo Beach

Frequently asked questions

Looking for a spa hotel in Los Osos?
Forget the stress of everyday life and book yourself a hotel with a spa. Check out the beaches in Los Osos - worth a picture or two! Take part in recreational activities such as golfing during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Los Osos?
Sea Pines Resort is a top spa hotel featuring a golf course, a bar, and a restaurant. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages, and couples treatments.
How many spa hotels will I find in Los Osos?
Among Expedia's 45 accommodation options in Los Osos, there is 1 spa hotel.
What's there to see and do in Los Osos?
Experience Los Osos with a stop at Los Osos Oaks State Reserve, Elfin Forest Preserve, and Montaña de Oro State Park. If you have a bit of extra time while you're in the area, you might want to check out Morro Bay State Park and Morro Coast Audubon Society Sweet Springs Nature Preserve.
What is a Los Osos spa hotel?
Spa hotels in Los Osos provide lodging and have an on-site spa which offers services such as facials as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

Explore a world of travel with Expedia