Get an overview of this hotelDowntown Louisville hotel on Museum Row

Expedia Insiders' Select Winner 2015

Near art museum

This downtown Louisville hotel is across from the Kentucky Museum of Art and Craft and the Louisville Science Center. The Louisville Slugger Museum is a block away.

On-site museum

21c Museum Hotel Louisville shares space with the 21c Museum. This Louisville hotel also offers an on-site restaurant and bar, a 24-hour business center, and decor with contemporary art.

42-inch LCD TVs

Guestrooms at 21c Museum Hotel Louisville include 42-inch LCD TVs, minibars, desks with ergonomic Herman Miller chairs, and luxurious bedding.

Hotel Amenities

Hotel Amenities

21c Museum Hotel Louisville inhabits a building on Louisville’s Museum Row that once held 19th-century tobacco and bourbon warehouses. Now, this modern hotel is bedecked with contemporary art, with its walls dedicated to works from the 21st century, a focus shared with the hotel’s on-site museum. This Louisville hotel features a restaurant serving breakfast, lunch, and dinner, all prepared with locally grown ingredients. The hotel also offers a bar, and room service is available from early morning to late night.

Shop at 21c offers artistic gifts, clothing, books, and accessories. The spa area offers massage and includes fitness equipment, a steam room, and a sauna. Yoga classes are available on site, and complimentary bicycles can be provided. The business center is open 24 hours a day, and the hotel offers complimentary wireless Internet access. For a surcharge, guests have access to a limo and valet parking. Coffee and newspapers are complimentary in the lobby. This smoke-free hotel also offers dry cleaning.

  • 24-hour business center 
  • 24-hour front desk 
  • ATM/banking 
  • Bar/lounge 
  • Breakfast available (surcharge) 
  • Coffee/tea in lobby 
  • Free newspapers in lobby 
  • Computer station 
  • Concierge services 
  • Conference space 
  • Conference space size (feet) - 5000 
  • Conference space size (meters) - 465 
  • Dry cleaning/laundry service 
  • Elevator/lift 
  • Fitness facilities 
  • Free WiFi 
  • Free wired high-speed Internet 
  • Gift shops or newsstand 
  • Limo or Town Car service available 
  • Luggage storage 
  • Meeting rooms 
  • Multilingual staff 
  • Number of buildings/towers - 1 
  • Number of floors - 4 
  • Number of meeting rooms - 7 
  • Porter/bellhop 
  • Restaurant 
  • Safe-deposit box at front desk 
  • Sauna 
  • Smoke-free property 
  • Spa treatment room(s) 
  • Steam room 
  • Total number of rooms - 90 
  • Tours/ticket assistance 
  • Valet parking (surcharge) 
  • Year Built 2006 

Family Friendly Amenities

  • Cribs/infant beds (complimentary)  
  • Free Wi-Fi  
  • Refrigerator (on request)  
  • Rollaway/extra beds available  


Available in all rooms: Free WiFi , Free wired high-speed Internet

Available in some public areas: Free WiFi , Free wired high-speed Internet


Valet parking (surcharge)

Room Amenities

  • Air conditioning 
  • Bathrobes 
  • Blackout drapes/curtains 
  • Cable TV service 
  • Climate control 
  • Coffee/tea maker 
  • Free bottled water 
  • Free newspaper 
  • Free toiletries 
  • Free cribs/infant beds 
  • Daily housekeeping 
  • Designer toiletries 
  • Desk 
  • Down comforter 
  • Free local calls 
  • Free WiFi 
  • Free wired high-speed Internet 
  • Hair dryer 
  • Hypo-allergenic bedding available 
  • In-room massage available 
  • In-room safe (laptop compatible) 
  • iPod docking station 
  • Iron/ironing board 
  • LCD TV 
  • Minibar 
  • Premium bedding 
  • Premium TV channels 
  • Private bathroom 
  • Refrigerator (on request) 
  • Rollaway/extra beds available 
  • Room service (limited hours) 
  • Shower/tub combination 
  • Turndown service 

Where to Eat

Proof on Main - Dishes bring together Italy and the American South. Ingredients come from local, sustainable farms or the restaurant’s own garden at Woodland Farm. Serving breakfast, lunch, and dinner.

Proof Bar - Serving more than fifty varieties of Kentucky bourbon. Seasonal cocktails.

Room Service - Available early morning to late night.

Nearby Things to Do

21c Museum Hotel Louisville’s spa area includes a sauna, a steam room, and a fitness center with weights and cardio machines.

The recreational activities listed below are available either on site or nearby; fees may apply.

  • Golfing nearby 
  • Free bicycles on site 
  • Hiking/biking trails nearby 
  • Bicycle rentals on site 
  • Yoga classes/instruction on site 
  • Boat tours nearby 

Spa Services

The spa at 21c Museum Hotel offers massages in 2 treatment rooms; advanced reservations are required.

  • Number of treatment rooms 2 
  • Massages 


To make requests for specific accessibility needs, complete the “Special or Accessibility Requests" section of “Trip Preferences" when you book your hotel.

  • Accessible path of travel 
  • Accessible bathroom 
  • Roll-in shower 
  • Accessible parking 
  • In-room accessibility 
  • Braille or raised signage 

Hotel Policies


Check-in time starts at 4 PM

Minimum check-in age is 21


Check-out time is 11 AM

Payment types

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are available for USD 30 per night.
  • Free cribs (infant beds)!


Pets allowed, Pet maximum weight in lb is 50

You need to know

Extra-person charges may apply and vary depending on hotel policy.

Government-issued photo identification and a credit card are required at check-in for incidental charges.

Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.

Service animals exempt from fees/restrictions

24-hour check-in


Optional extras

The following fees and deposits are charged by the property at time of service, check-in, or check-out.
  • Valet parking fee: USD 26 per night (in/out privileges)
  • Pet fee: USD 150.00 per accommodation, per stay
  • Rollaway bed fee: USD 30 per night
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

We should mention

Reservations are required for massage services. Reservations can be made by contacting the hotel prior to arrival, using the contact information on the booking confirmation.

Awards & Affiliations

  • 21c Museum Hotel Louisville is listed in the 2013 Condé Nast Traveler Gold List of the world's best places to stay and the 2013 Travel + Leisure 500.
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