Lupus Vacation Rentals

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Dec 26 - Dec 28
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In four months
Apr 3 - Apr 5

Vacation Rentals in Lupus

Exterior
Quiet Riverfront Cottage on Missouri River

Cottage in Jamestown

9.0 out of 10, Wonderful, (13)
"The stay was a wonderful "
United States
PAUL S.
$178 nightly
The price is $178
Dec 9 - Dec 10
Total with taxes and fees
Quiet Riverfront Cottage on Missouri River
Exterior
Step Back in Time Near The Missouri River

Cottage in Jamestown

9.8 out of 10, Exceptional, (17)
"It was a very cool house and in an awesome location! The place was very clean, and not to long of a drive to get to Columbia!"
United States
Jeffrey H.
$206 nightly
The price is $206
Dec 9 - Dec 10
Total with taxes and fees
Step Back in Time Near The Missouri River
Outdoor dining
South central 4 bedroom house 3 minutes from Faurot Field! Its close and quiet.

Vacation Home in Columbia

10.0 out of 10, Exceptional, (70)
"Very nice accommodations, perfect location and size for our needs."
United States
Donna B.
South central 4 bedroom house 3 minutes from Faurot Field! Its close and quiet.
Fridge, microwave, oven, stovetop
Katy Trail Pull Off

Vacation Home in Boonville

9.6 out of 10, Exceptional, (99)
"Great home, quiet neighborhood, and comfy beds. Perfect home for our stay and we will stay again. "
United States
Samantha H.
$165 nightly
The price is $178
Dec 9 - Dec 10
Total with taxes and fees
Katy Trail Pull Off
Fridge, microwave, oven, stovetop
Luxury Modern Downtown Columbia Lofts. 2 Beds, 2 Baths

Apartment in North Central Columbia

10.0 out of 10, Exceptional, (111)
"Excellent location "
United States
Kerry H.
Luxury Modern Downtown Columbia Lofts. 2 Beds, 2 Baths
Outdoor dining
Unique traincar stay at the Katy Caboose!

Cottage in Hartsburg

9.4 out of 10, Exceptional, (10)
"We loved the 3 taverns in town. Great vibe in a tiny town. "
United States
Dusty
$167 nightly
The price is $176
Dec 21 - Dec 22
Total with taxes and fees
Unique traincar stay at the Katy Caboose!
Fridge, microwave, oven, stovetop
Spacious & Cozy near Downtown ~ HotTub ~ Game Room

Vacation Home in Columbia

10.0 out of 10, Exceptional, (55)
"The house was great for all of us to stay together for our family reunion. "
United States
Anonymous traveler
$611 nightly
The price is $640
Dec 9 - Dec 10
Total with taxes and fees
Spacious & Cozy near Downtown ~ HotTub ~ Game Room
Microwave, oven, stovetop, dishwasher
Upscale 2-bedroom luxury loft in vibrant downtown Columbia, MO, in The District

Condo in Columbia

2.0 star property
10.0 out of 10, Exceptional, (1)
"Amazing loft condo in an amazing location, heart of downtown Columbia. Highly recommend"
United States
Adam F.
Upscale 2-bedroom luxury loft in vibrant downtown Columbia, MO, in The District
Smart TV
3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou

Vacation Home in Columbia

10.0 out of 10, Exceptional, (24)
"Just passing through town for a visit "
United States
Lori M.
$251 nightly
The price is $253
Dec 11 - Dec 12
Total with taxes and fees
3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou
Property grounds
Glamping MoonRise Cabin-Serene & Unique off Katy Trail

Cabin in Hartsburg

9.8 out of 10, Exceptional, (7)
"The staff was very helpful. It was a nice secluded place to stay."
United States
Jason
$151 nightly
The price is $159
Dec 9 - Dec 10
Total with taxes and fees
Glamping MoonRise Cabin-Serene & Unique off Katy Trail
Interior
Short term avail! 5 min from MIZZOU,Univ Hospital! Family sized,clean,fenced

Vacation Home in Columbia

9.8 out of 10, Exceptional, (37)
"Wonderful place to stay in Columbia!"
United States
Michael G.
Short term avail! 5 min from MIZZOU,Univ Hospital! Family sized,clean,fenced
Private kitchen
Newly Renovated 3 Bedroom in the Heart of Columbia

Condo in Columbia

10.0 out of 10, Exceptional, (19)
"Enjoyed our stay. "
United States
Timothy
Newly Renovated 3 Bedroom in the Heart of Columbia
Fridge, microwave, oven, stovetop
3 Bedroom 1 Bath Pet Friendly 5 min to MU

Vacation Home in Columbia

10.0 out of 10, Exceptional, (9)
"Very clean and cute home! Great location, close to coffee shops and restaurants. We enjoyed our stay!"
United States
Lori S.
$223 nightly
The price is $223
Dec 9 - Dec 10
Total with taxes and fees
3 Bedroom 1 Bath Pet Friendly 5 min to MU
Fridge, microwave, oven, stovetop
Newly Built Home w/ Fresh Design!

Vacation Home in Columbia

9.8 out of 10, Exceptional, (22)
"We had a great overnight stay. Very cozy and nice. "
United States
Delia G.
$319 nightly
The price is $319
Dec 9 - Dec 10
Total with taxes and fees
Newly Built Home w/ Fresh Design!
Pool
Super Close to Mizzou Condo 2 Bed 1 Bath

Apartment in Columbia

10.0 out of 10, Exceptional, (8)
"The property was in a very convenient location and the property owner was ver responsive.I would stay again!!"
United States
Carmen H.
Super Close to Mizzou Condo 2 Bed 1 Bath
Fridge, microwave, oven, stovetop
Cozy Home Mins to Hospitals*District*Mizzou*Parks

Vacation Home in Columbia

10.0 out of 10, Exceptional, (3)
"Great space and location. Very comfortable unit with peaceful neighborhood."
United States
Tim R.
Cozy Home Mins to Hospitals*District*Mizzou*Parks
Smart TV
Brand New Modern Downtown Condo designed by award-winning architect!

Condo in Columbia

10.0 out of 10, Exceptional, (83)
"It was clean and very nice- close to Mizzou campus so very convenient for our stay- will stay again!"
United States
Kristin G.
$343 nightly
The price is $343
Jan 8 - Jan 9, 2026
Total with taxes and fees
Brand New Modern Downtown Condo designed by award-winning architect!
Fridge, microwave, oven, stovetop
Remodeled Home - Near Faurot Field!

Vacation Home in Columbia

8.6 out of 10, Excellent, (34)
"Good location. Property has plenty of room for all who stayed."
United States
Joans C.
Remodeled Home - Near Faurot Field!
Fridge, microwave, oven, stovetop
It's a Gem ! Comfy Hideaway for R & R ~ King Bed !

Vacation Home in Columbia

9.8 out of 10, Exceptional, (20)
"Everything was great from check in to check out. "
United States
Jason L.
$342 nightly
The price is $354
Dec 14 - Dec 15
Total with taxes and fees
It's a Gem ! Comfy Hideaway for R & R ~ King Bed !
Exterior
Cozy cabin getaway with hot-tub under stars!

Cabin in Ashland

9.6 out of 10, Exceptional, (21)
"We loved the remote location and the quiet and peacefulness of our stay"
United States
Kevin M.
$239 nightly
The price is $239
Dec 9 - Dec 10
Total with taxes and fees
Cozy cabin getaway with hot-tub under stars!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lupus Hotel Reviews

Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard

10/10 Excellent
"We had a last-minute change in our plans and picked up this hotel on way. We were not able to make the dinner time snacks or the complementary drinks. The room was comfortable and very clean. The pillows were comfortable. The sound in the room was absolutely fantastic. No outside noise no distracting ice machine couldn’t even hear the highway! The buffet breakfast was fantastic other than the pot machine happen to be broken that morning. Everyone bent over backwards to make sure that our stay was completely comfortable and every way. Will definitely stay here again. "
Nancy 1-night trip
Posted 3 days ago
Drury Inn & Suites Columbia Stadium Boulevard

Find out more about Lupus

Everything you need to know about Lupus vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Lupus vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Lupus vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Lupus vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Lupus. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Lupus in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $159 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Lupus rentals

At Expedia, we put the best Lupus vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Lupus rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Lupus vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Lupus. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in Lupus?

Yes, there are vacation rentals near the most popular points of interest in Lupus, or you can choose a secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals that Lupus has to offer?

Spacious & Cozy near Downtown ~ HotTub ~ Game Room : This vacation home rental near Lupus offers an arcade game room, a hot tub, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What can I see and do in Lupus?

Explore the area and family-friendly sights such as Warm Springs Ranch, or get out into nature at a spot like Shelter Gardens. In the larger area, you’ll find Rock Bridge Memorial State Park and Mizzou Arena.

What are vacation rentals like in Lupus?

Vacation rentals are privately owned accommodations you can reserve for a few days or a quick weekend in Lupus. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, vacation rentals can provide a sense of privacy away from public hotel elevators and busy front desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive option for a family trip or a small group gathering.