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Lupus Vacation Rentals

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Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for Lupus vacation rentals

An old brick building with a sign reading "Lupus General Store."

1. Quiet Riverfront Cottage on Missouri River

Quiet Riverfront Cottage on Missouri River
Jamestown
8.8 out of 10, Excellent, (16 reviews)
"What a cute little place. We were pleased with our stay. Host was great. Make sure you check out the garden! Just beautiful!"
United States
Shannon K.
$173 nightly
The price is $184
Oct 14 - Oct 15
Total with taxes and fees
Quiet Riverfront Cottage on Missouri River
A two-story brick building with a sign reading "Lupus General Store".

2. Step Back in Time Near The Missouri River

Step Back in Time Near The Missouri River
Jamestown
9.8 out of 10, Exceptional, (24 reviews)
"Perfect spot!"
United States
Nicole
$243 nightly
The price is $258
Oct 14 - Oct 15
Total with taxes and fees
Step Back in Time Near The Missouri River
An open refrigerator with multiple shelves and a water dispenser.

3. 3 Bed 1.5 Bath Pet Friendly Apt

3 Bed 1.5 Bath Pet Friendly Apt
Columbia
10.0 out of 10, Exceptional, (13 reviews)
"Property was clean and comfortable and host was attentive."
United States
Stephanie A.
$205 nightly
The price is $205
Oct 19 - Oct 20
Total with taxes and fees
3 Bed 1.5 Bath Pet Friendly Apt
A kitchen with dark cabinets, a stainless steel refrigerator, a microwave, and a dishwasher.

4. ~A Home Away From Home~Sleeps 8~

~A Home Away From Home~Sleeps 8~
Columbia
9.6 out of 10, Exceptional, (8 reviews)
"I stayed here for work. It was a great place to stay, close to everything and nice. I will be back when we come back for work. Thanks! Kevin"
United States
Kevin G.
$269 nightly
The price is $284
Oct 14 - Oct 15
Total with taxes and fees
~A Home Away From Home~Sleeps 8~
A stone-walled entrance with a white door, a number '3' sign, and a small outdoor light fixture.

5. Super Close to Mizzou Condo 2 Bed 1 Bath

Super Close to Mizzou Condo 2 Bed 1 Bath
Columbia
10.0 out of 10, Exceptional, (19 reviews)
"The stay was great. Clean, quiet, comfortable, well equipped. Also very convenient location"
United States
William
$205 nightly
The price is $205
Oct 15 - Oct 16
Total with taxes and fees
Super Close to Mizzou Condo 2 Bed 1 Bath
A hallway with a blue-lit wall-mounted light fixture, a door leading to another room, and a wooden table in the foreground.

6. Como's Finest- A Home Away From Home- Sleeps 10

Como's Finest- A Home Away From Home- Sleeps 10
Columbia
9.4 out of 10, Exceptional, (8 reviews)
"Great place for a weekend trip"
United States
Brandon W.
$275 nightly
The price is $289
Oct 14 - Oct 15
Total with taxes and fees
Como's Finest- A Home Away From Home- Sleeps 10
A narrow hallway with a wooden bench on the right, a rocking chair in the center, and a bed at the end.

7. The Katy Caboose in Hartsburg

The Katy Caboose in Hartsburg
Hartsburg
10.0 out of 10, Exceptional, (2 reviews)
"Fun little place right on the Katy Trail. Hosts were very responsive, and we enjoyed our stay. Know two things: 1) bathroom is in a separate building next door; 2) food choices, especially before the weekend, are almost non existent. But that's not the owners fault-they provided a great place to stay and we will do so again next time we are on the Katy. Thanks!"
United States
Mike G.
$195 nightly
The price is $206
Oct 15 - Oct 16
Total with taxes and fees
The Katy Caboose in Hartsburg
A spacious living area with a sofa, a patterned ottoman, and a fireplace.

8. Whispering Woods Hideaway ~ Large Home ~ 85 in TV

Whispering Woods Hideaway ~ Large Home ~ 85 in TV
Columbia
10.0 out of 10, Exceptional, (5 reviews)
"Clean house. Very responsive"
United States
Gary B.
$453 nightly
The price is $476
Oct 20 - Oct 21
Total with taxes and fees
Whispering Woods Hideaway ~ Large Home ~ 85 in TV
A white entertainment center with a flat-screen TV, decorative items, and a remote control.

9. 10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!

10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!
Columbia
9.8 out of 10, Exceptional, (50 reviews)
"Very comfortable and friendly host!"
United States
Troy V.
$197 nightly
The price is $211
Oct 14 - Oct 15
Total with taxes and fees
10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!
A modern kitchen with dark cabinets, stainless steel appliances, and a wooden dining table.

10. 3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena

3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
Columbia
9.6 out of 10, Exceptional, (15 reviews)
"Great place to stay! "
United States
Stacy B.
$329 nightly
The price is $346
Oct 14 - Oct 15
Total with taxes and fees
3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
A hallway with a dining area, a door, a wall-mounted sign, a potted plant, and a small table with a lamp.

11. Comfy Home~Teal Feel~ Sleeps 8

Comfy Home~Teal Feel~ Sleeps 8
Columbia
8.4 out of 10, Very good, (8 reviews)
"Went there for work. Great place to stay. Loved the beds, very comfortable. I will stay there again when I come back."
United States
Kevin G.
$233 nightly
The price is $245
Oct 18 - Oct 19
Total with taxes and fees
Comfy Home~Teal Feel~ Sleeps 8
A living room with a flat-screen TV displaying a streaming service interface, a dark-colored sofa with a knitted throw pillow, a coffee table, and a rug.

12. Heying Essentials

Heying Essentials
Columbia
8.8 out of 10, Excellent, (3 reviews)
"Nice place when in town for a game."
United States
Robert H.
$256 nightly
The price is $269
Oct 14 - Oct 15
Total with taxes and fees
Heying Essentials
A spacious living room with a brown sofa, wooden chairs, a coffee table, and a ceiling fan.

13. Quaint cottage w/ direct access to Katy Trail!

Quaint cottage w/ direct access to Katy Trail!
Hartsburg
10.0 out of 10, Exceptional, (2 reviews)
"They were so nice! Super clean, great place to stay!"
United States
Taylor R.
$208 nightly
The price is $220
Oct 19 - Oct 20
Total with taxes and fees
Quaint cottage w/ direct access to Katy Trail!
An outdoor patio area with wicker furniture, a fire pit, and a covered seating area.

14. Accessible Studio Suite w/ Breakfast Included, Near Mizzou

Accessible Studio Suite w/ Breakfast Included, Near Mizzou
Columbia
$153 nightly
The price is $170
Oct 25 - Oct 26
Total with taxes and fees
Accessible Studio Suite w/ Breakfast Included, Near Mizzou
A covered outdoor patio with a table and chairs, a grill, and a stone pillar base.

15. King Studio w/ Kitchen | Free Hot Breakfast + Pool

King Studio w/ Kitchen | Free Hot Breakfast + Pool
Columbia
$153 nightly
The price is $170
Oct 25 - Oct 26
Total with taxes and fees
King Studio w/ Kitchen | Free Hot Breakfast + Pool
A modern kitchen with a stainless steel refrigerator, wooden flooring, and a tiled backsplash.

16. Downtown Luxury Suite

Downtown Luxury Suite
Columbia
9.8 out of 10, Exceptional, (87 reviews)
"Wonderful locationFun spaceWe would definitely stay here again"
United States
Andrew M.
$205 nightly
The price is $220
Oct 15 - Oct 16
Total with taxes and fees
Downtown Luxury Suite
A cozy bedroom with a bed, a wooden table, a chair, and a staircase.

17. Cozy cabin getaway with hot-tub under stars!

Cozy cabin getaway with hot-tub under stars!
Ashland
9.6 out of 10, Exceptional, (31 reviews)
"This is our second time staying here and we love it. Such a peaceful relaxing place."
United States
Ryan L.
$237 nightly
The price is $250
Oct 19 - Oct 20
Total with taxes and fees
Cozy cabin getaway with hot-tub under stars!
A staircase with wooden steps and white railings, leading to a second floor.

18. Restored 2-bedroom cottage in beautiful California, MO

Restored 2-bedroom cottage in beautiful California, MO
California
10.0 out of 10, Exceptional, (1 review)
"The house was warm & cozy, bed super comfortable. Very cute historic home, we enjoyed our stay!"
United States
Shelley F.
$200 nightly
The price is $216
Oct 15 - Oct 16
Total with taxes and fees
Restored 2-bedroom cottage in beautiful California, MO
A bedroom with a fireplace, a TV mounted above it, a bed with a blue blanket, and a blue armchair with a patterned pillow.

19. Historic Cozy Apartment 1 Bedroom In Peaceful Boonville

Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
Boonville
9.6 out of 10, Exceptional, (26 reviews)
"Very comfy and cozy stay. Would highly recommend!"
United States
Sam K.
$183 nightly
The price is $198
Oct 25 - Oct 26
Total with taxes and fees
Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
A compact kitchen with a refrigerator, sink, and stove, a dining table with chairs, and a view through a sliding glass door.

20. Cozy, well appointed 3-bedroom, 1.5-bath house 10 min from Mizzou

Cozy, well appointed 3-bedroom, 1.5-bath house 10 min from Mizzou
Columbia
10.0 out of 10, Exceptional, (5 reviews)
"The space was VERY clean. We walked about in bare feet, and our feet stayed clean. It really helped us to relax and enjoy the place. The kitchen was well stocked. We cooked a few times, and found all the utensils/pots and pans we needed. Beds were quite comfortable. While we could not walk to any thing, it was a very short drive to anything we wanted or needed (by short we mean less than 15 minutes). The neighborhood was quiet at night (even though it was during the 4th of July). The...
United States
Matt K.
Cozy, well appointed 3-bedroom, 1.5-bath house 10 min from Mizzou
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lupus Hotel Reviews

Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

10/10 Excellent
"Cheerful, clean room. Friendly, helpful staff. Great overbight stay."
Donna 1-night trip
Posted 2 hours ago
Best Western Plus Columbia Inn

Find out more about Lupus

Everything you need to know about Lupus vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Lupus vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Lupus vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Lupus vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Lupus. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Lupus in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $176 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Lupus rentals

At Expedia, we put the best Lupus vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Lupus rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Lupus vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Lupus. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Lupus?

Yes, there are vacation rentals near the most popular points of interest in Lupus, or you can choose a secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals that Lupus has to offer?

The Stone & Bridge: Close to MKT Trail & Dog Park, Dining, Groceries & I-70: This vacation home rental near Lupus offers a patio, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What can I see and do in Lupus?

Explore the area and family-friendly sights such as Warm Springs Ranch, or get out into nature at a spot like Shelter Gardens. In the larger area, you’ll find Rock Bridge Memorial State Park and Mizzou Arena.

What are vacation rentals like in Lupus?

Vacation rentals are privately owned accommodations you can reserve for a few days or a quick weekend in Lupus. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, vacation rentals can provide a sense of privacy away from public hotel elevators and busy front desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive option for a family trip or a small group gathering.