Mackenzie Vacations from $235

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Your Mackenzie Vacation

Reserve a Mackenzie vacation package and prepare to experience all this lively city has to offer. Consider basing yourself in the neighborhood of Soulard, which is great for distilleries and craft breweries, bars and pubs and markets. A trip to Mackenzie is a great opportunity to see the sights. Check out big-name attractions such as St. Louis Zoo, Grants Farm and St. Louis Art Museum. Check out Expedia's wide range of travel options and begin planning your ultimate vacation to Mackenzie now.

The Latest Mackenzie Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Price was $343, price is now $235 per person
$235
per person
Feb 6 - Feb 9
found 6 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.2/10 Very Good! (779 reviews)
Just a really nice hotel tucked away from everything, but still close to get whereevre you need to go!

Reviewed on Oct 26, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $510, price is now $254 per person
$254
per person
Feb 6 - Feb 9
found 6 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Very clean very safe

Reviewed on Dec 9, 2025

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
Grand Center
Price was $388, price is now $281 per person
$281
per person
Feb 6 - Feb 9
found 6 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.8/10 Excellent! (1,022 reviews)
Extremely cool hotel.

Reviewed on Dec 9, 2025

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
Price was $360, price is now $265 per person
$265
per person
Feb 6 - Feb 9
found 6 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.4/10 Very Good! (2,194 reviews)
Everything was great. Keep up the good work!

Reviewed on Dec 10, 2025

Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport

2.5 out of 5
Woodson Terrace
Price was $347, price is now $256 per person
$256
per person
Feb 6 - Feb 9
found 6 hours ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.8/10 Excellent! (96 reviews)
Excellent new pretty room

Reviewed on Dec 4, 2025

Where to stay in Mackenzie

Find the best Mackenzie areas and neighborhoods for the activities you enjoy most. Learn more about Mackenzie
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Find hotels in Downtown St. Louis

Mackenzie Hotel Deals

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $105 total per night from Dec 21 to Dec 22
$105 total
Dec 21 - Dec 22
Total with taxes and fees
8.4/10 Very Good! (3,999 reviews)
The room was very nice and clean, but the lights went out and there was no hot water to bathe; on the 29&30. Also, I was not told about the 75 dollars incidental fee per night.which caused my family to spend money not in our budget for our Thanksgiving Trip.

Reviewed on Dec 4, 2025

Hyatt Regency St. Louis at The Arch
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $111 total per night from Dec 25 to Dec 26
$111 total
Dec 25 - Dec 26
Total with taxes and fees
8.6/10 Excellent! (1,142 reviews)
The staff was great !!!

Reviewed on Dec 7, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $111 total per night from Dec 16 to Dec 17
$111 total
Dec 16 - Dec 17
Total with taxes and fees
8.6/10 Excellent! (1,160 reviews)
Clean Room, the view was amazing, the game room was perfect to help calm my daughter the morning of her procedure at the Children’s Hospital.

Reviewed on Dec 6, 2025

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
See all 1,778 properties in Mackenzie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
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Beach Vacations
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Kid Friendly Vacations

Discover the most popular places to visit in Mackenzie

St. Louis Union Station

St. Louis Union Station

4/5(615 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
Gateway Arch showing a city, a skyscraper and skyline

Gateway Arch

4.5/5(2,511 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

4.5/5(1,212 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

Things to do

St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$32
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

$169
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
Step into the shadows and discover the haunting tales of our city's past.

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

$30
per adult
100% of travellers recommend
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
See all activities in St. Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.