Find luxury hotels in Macon, MO

Start date: Check-in selected.
To Date
End date: Check-out
  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check availability on Macon Luxury Hotels

This weekend
Next weekend

Top Macon Luxury Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in Macon

Briggs Convenience Haven, Briggs Convenience Haven

2.0 star property
Macon
10.0 out of 10, Exceptional, (4)
"Clean house with very comfortable beds. "
United States
Paul H.
$264 nightly
The price is $264
Dec 30 - Dec 31
Total with taxes and fees
Briggs Convenience Haven, Briggs Convenience Haven

Mallard Cottage - At the Lodges of Long Branch

Bevier Township
$269 nightly
The price is $279
Dec 10 - Dec 11
Total with taxes and fees
Mallard Cottage - At the Lodges of Long Branch

Blue Heron Hut - At the Lodges of Long Branch

Bevier Township
$246 nightly
The price is $256
Dec 10 - Dec 11
Total with taxes and fees
Blue Heron Hut - At the Lodges of Long Branch

Hampton Inn Kirksville

2.5 star property
Kirksville
9.2 out of 10, Wonderful, (570)
"Clean and very friendly staff"
United States
David
$118 nightly
The price is $133
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hampton Inn Kirksville

Unwind on Vine

Macon
9.4 out of 10, Exceptional, (22)
"The house was very nice and clean. Will stay again!!"
United States
Ashley G.
$160 nightly
The price is $160
Dec 10 - Dec 11
Total with taxes and fees
Unwind on Vine

Holiday Inn Express & Suites Kirksville - University Area by IHG

2.5 star property
Kirksville
9.2 out of 10, Wonderful, (508)
"Staff was polite and helpful!"
United States
Rochelle
$111 nightly
The price is $126
Dec 21 - Dec 22
Total with taxes and fees
Holiday Inn Express & Suites Kirksville - University Area by IHG

Depot Inn and Suites

3.5 star property
La Plata
9.8 out of 10, Exceptional, (613)
"Fantastic stay, highly recommended .... will definitely be coming back."
United States
Chad
$84 nightly
The price is $92
Dec 28 - Dec 29
Total with taxes and fees
Depot Inn and Suites

Comfort Inn & Suites Moberly

2.5 star property
Moberly
8.4 out of 10, Very Good, (423)
"Great staff!"
United States
michael
$91 nightly
The price is $102
Jan 8 - Jan 9, 2026
Total with taxes and fees
Comfort Inn & Suites Moberly

Teal Nest - at The Lodges of Long Branch

Bevier Township
10.0 out of 10, Exceptional, (2)
"Great place to stay and relax. Great Italian Food close by -Ugo;s. Will stay here again next year"
United States
Vincent H.
$165 nightly
The price is $170
Dec 11 - Dec 12
Total with taxes and fees
Teal Nest - at The Lodges of Long Branch

Super 8 by Wyndham Macon

2.0 star property
Macon
7.8 out of 10, Good, (668)
"quiet location, comfortable rooms."
United States
laszlo
$72 nightly
The price is $79
Jan 1 - Jan 2, 2026
Total with taxes and fees
Super 8 by Wyndham Macon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Macon

Maconand its attractions for luxury travelers

For luxury travelers visiting Macon, Missouri, the region offers a delightful blend of history, nature, and unique experiences. Start your exploration at the Macon County Historical Society Museum, where you can delve into the rich local heritage with beautifully curated exhibits that showcase the area’s past. For those who appreciate nature, the nearby Long Branch State Park presents a serene escape, perfect for leisurely hikes or a relaxing day by the water, complete with stunning views. The charming downtown area features local boutiques and artisan shops, allowing for a unique shopping experience filled with handcrafted goods. If you're a golf enthusiast, the Macon Country Club offers a well-maintained course where you can enjoy a round or two amidst picturesque landscapes. After a day of adventures, unwind in one of the upscale hotels in the heart of Macon, where attentive service and luxurious amenities await. Enjoy plush accommodations that provide a soothing retreat, along with easy access to local attractions, ensuring your stay is both convenient and pampered.

Top Macon Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in Macon?
Use Expedia to help you arrange a flight to Kirksville, MO (IRK-Kirksville Municipal) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Macon has to offer. During your visit, you might want to enjoy the university which Macon is known for.
When can I expect good weather in Macon?
Planning for the weather is a good way to make your trip to Macon relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 73°F, while the coldest months are January and February with an average of 34°F. The snowiest months in Macon are January, November, February, and December, with each month seeing an average of 5 inches of snowfall.
What's there to see and do in Macon?
Enjoy all that Macon has to offer when you visit Long Branch State Park, Maples Repertory Theatre, and West Winery. If you have a little extra time during your trip, you might want to check out La Plata Golf Course and Stephen's Park.

Explore a world of travel with Expedia