Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top Manhattan Neighborhoods for Business Hotels

Midtown East
140 hotels
from

$93

Midtown West
161 hotels

YOTEL New York

4.5 out of 5.0
from

$82

Wall Street
0 hotels
from

$116

Featured Manhattan Business Hotels

See all 828 Hotels in Manhattan
The Roosevelt Hotel, New York City

The Roosevelt Hotel, New York City

45 E 45th Street, New York
4.5 out of 5.0
3.7 out of 5 (21,293 reviews)
Excellent hotel, great location. Staff friendly
  Dec 16, 2017

$93

$93
YOTEL New York

YOTEL New York

570 Tenth Avenue, New York
4.5 out of 5.0
4.3 out of 5 (9,480 reviews)
Fab hotelPerfect location 5 mins from Times Square. Friendly helpful staff, spotlessly clean, Wi-fi will definitely be staying again
  Dec 16, 2017

$82

$82
Pod 39

Pod 39

145 East 39th Street, New York
3.5 out of 5.0
4.2 out of 5 (9,674 reviews)
Incredible small but all you needIncredibly different type of experience. Obviously Japanese run, very modern, minimal but extremely and delightfully colorful, and youthful, extremely friendly/ accommodating employees. The ambiance is also casual, almost funky but stays on the side of being tastefully done. Very clean and the bed ...
  Dec 15, 2017

$95

$95
Wyndham New Yorker

Wyndham New Yorker

481 Eighth Ave., New York
4.5 out of 5.0
3.9 out of 5 (16,505 reviews)
in a good location but shows its ageThe location was very convenient, especially if you're using Penn Station. I got in late and checked in about 1:30 a.m. and wanted to sleep in late. At 9:00 a.m. maintenance/construction started right outside my window with very loud grinding noise. Staff switched my room right away but it was a ...
  Dec 17, 2017

$98

$98
Club Quarters Hotel, Wall Street

Club Quarters Hotel, Wall Street

52 William St, New York
4.5 out of 5.0
4.2 out of 5 (3,765 reviews)
Ok for a couple of nights Bathrooms are in desperate need of a refurb. They are tatty and falling apart. Aside from that the hotel is well situated.
  Dec 15, 2017

$116

$116
Row NYC

Row NYC

700 8th Avenue, New York
4.5 out of 5.0
3.6 out of 5 (10,369 reviews)
Room was on the small side, but overall a pleasant experience.
  Dec 17, 2017

$86

$86
Stewart Hotel

Stewart Hotel

371 7th Ave, New York
4.5 out of 5.0
4.0 out of 5 (7,853 reviews)
Close to Madison square garden and Penn station. Walking distance to time square
  Dec 13, 2017

$86

$86
Club Quarters Hotel, opposite Rockefeller Center

Club Quarters Hotel, opposite Rockefeller Center

25 West 51st St Entrance A, New York
4.5 out of 5.0
4.1 out of 5 (3,463 reviews)
Great location Great location, friendly helpful staff, comfortable rooms
  Dec 16, 2017

$125

$125
Pod 51

Pod 51

230 E 51st St, New York
3.5 out of 5.0
4.1 out of 5 (13,547 reviews)
Ship Cabin on landNoise from the hallway was annoying, but didn’t hear noise from adjoining rooms. Pleasant
  Dec 14, 2017

$90

$90
Hotel Metro

Hotel Metro

45 W 35th St, New York
3.5 out of 5.0
4.3 out of 5 (3,211 reviews)
Very clean and nice hotel, took the double bed room mini and its actually really good for one night for a person and even two!
  Dec 17, 2017

$101

$101
Club Quarters Hotel, Grand Central

Club Quarters Hotel, Grand Central

128 East 45th Street, New York
4.5 out of 5.0
4.4 out of 5 (1,344 reviews)
Perfect!Close to all the action on Broadway, close to Grand Central for easy access to subway. Some Hotels we have stayed at in NY barely have enough room to move around the bed, CQ room is comfortable with enough space and design to not feel so cramped. There is a table with a couch around it that can be ...
  Dec 17, 2017

$116

$116
The Lexington New York City, Autograph Collection

The Lexington New York City, Autograph Collection

511 Lexington Ave at 48th St., New York
4.5 out of 5.0
4.1 out of 5 (3,515 reviews)
Great location to DO ManhattanOverall, a nice hotel - rooms have a European feel (ie VERY small, tight, especially bathroom)....although it adds to the charm, it was a little “too charming”. No towels were in the room when we checked in, but when we left for dinner the on duty manager was there and personally made sure they were ...
  Dec 8, 2017

$127

$127
Hotel Edison

Hotel Edison

228 W 47th St, New York
3.5 out of 5.0
3.7 out of 5 (15,565 reviews)
Hotel with convenience Nice hotel but my client said it was noisy but loved the convenience to Time Square They liked the restaurant inside the Edison.
  Dec 16, 2017

$106

$106
The Belvedere Hotel

The Belvedere Hotel

319 W 48th St, New York
4.0 out of 5.0
4.2 out of 5 (17,706 reviews)
Great hotel for a visit!A beautiful hotel nearing 100 years old with all the amenities. The hotel has a very friendly staff that take care of you. The room was very clean and comfortable. I would recommend anyone to book their stay at the Belvedere.
  Dec 17, 2017

$135

$135
Executive Hotel Le Soleil New York

Executive Hotel Le Soleil New York

38 W 36th St, New York
4.0 out of 5.0
4.4 out of 5 (903 reviews)
Location vs. sizeGreat location - central to many of NYC attractions, close to underground. First room was extremely small and should never be offered to two occupants (no room for 2 suitcases for ne). The other (with higher charge) was very satisfying. Again - great location.
  Dec 17, 2017

$149

$149
Arlo NoMad

Arlo NoMad

11 East 31st Street, New York
4.5 out of 5.0
4.5 out of 5 (477 reviews)
Great convenient location. Nice staff. Clean and comfy. Elevators a bit slow. Overall — Would stay here again!
  Dec 15, 2017

$161

$161
The Jewel facing Rockefeller Center

The Jewel facing Rockefeller Center

11 West 51st Street, New York
4.5 out of 5.0
4.4 out of 5 (4,440 reviews)
Location, location, location! This hotel is perfectly located. You walk outside the front door and straight ahead is the Rockefeller Christmas tree. To the right is radio city music hall. To the left is Saint Patrick’s cathedral. Just perfectly located in the middle of it all. No taxi or Uber necessary, you are able to walk to ...
  Dec 17, 2017

$125

$125
Wellington Hotel

Wellington Hotel

871 Seventh Ave, New York
3.5 out of 5.0
3.7 out of 5 (12,372 reviews)
Close to Central Park The staff was super friendly and we loved the retro decor. This hotel is an Art Deco masterpiece! If you’re looking for contemporary this not the place for you. I did appreciate that the toiletries provided are cruelty free.
  Dec 16, 2017

$83

$83
New York Hilton Midtown

New York Hilton Midtown

1335 Avenue Of The Americas, New York
4.5 out of 5.0
4.1 out of 5 (12,926 reviews)
Great great location. Close to everything!!!Great location right between Central Park and Times Square. Radio city a five minute walk. Our room was kinda small but he did have a view of the plaza and Central Park in th distance.
  Dec 14, 2017

$171

$171
Club Quarters Hotel, Midtown

Club Quarters Hotel, Midtown

40 W 45th St, New York
4.5 out of 5.0
4.1 out of 5 (3,589 reviews)
Great LocationLocated really close to almost everything you'd want to do in Manhattan. Staff was professional and friendly, hotel was clean and pristine, room was a bit small, but for the price, we loved the stay!
  Dec 14, 2017

$134

$134
Map

Recently booked Business Hotels in Manhattan

The Roosevelt Hotel, New York City
4.5 out of 5.0
Last booking: 1 minute ago
NoMo SoHo
4.0 out of 5.0
Last booking: 1 minute ago
YOTEL New York
4.5 out of 5.0
Last booking: 4 minutes ago
The Marmara Park Avenue
5.0 out of 5.0
Last booking: 4 minutes ago
The NoMad Hotel
5.0 out of 5.0
Last booking: 5 minutes ago
Hotel 31
2.5 out of 5.0
Last booking: 7 minutes ago
Orchard Street Hotel
3.5 out of 5.0
Last booking: 7 minutes ago
Millennium Hilton New York One UN Plaza
4.0 out of 5.0
Last booking: 8 minutes ago
Kimpton Ink48 Hotel
5.0 out of 5.0
Last booking: 8 minutes ago

Pocket Guide: Business Hotels in Manhattan

Search for hotels in Manhattan on Expedia. You can easily find your hotels in Manhattan using one of the methods below:

  • View our selection of featured hotels in Manhattan
  • Use the map to find hotels in the Manhattan neighborhood you prefer
  • Use the filters to see hotels in a specific area of Manhattan, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Manhattan
  • Enter your travel dates to view the best deals on hotels in Manhattan - while they last