Mayo Vacations from $289

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The Latest Mayo vacation packages

Price found within the past 48 hours. Click for updated prices.
Horizon Inn & Suites

Horizon Inn & Suites

2 out of 5
Price was $402, price is now $289 per person
$289
per person
Oct 9 - Oct 12
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
5/10 (193 reviews)
Quiet stay, rooms are clean, everyone is nice

Reviewed on Jun 30, 2025

Zoka - Modern Mountain Retreat

Zoka - Modern Mountain Retreat

2 out of 5
Save 100% on your flight
Price was $2,057, price is now $1,230 per person
$1,230
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip flight included
New York (NYC) to Greenville (GSP)
No reviews
Hilton Greenville

Hilton Greenville

3.5 out of 5
Price was $674, price is now $493 per person
$493
per person
Nov 13 - Nov 17
found 16 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Greenville (GSP)
8/10 Very Good! (1,011 reviews)
Super clean and well kept, staff were super nice, and the location is great. The bed was really comfy too. No complaints at all — would definitely stay here again!

Reviewed on Aug 24, 2025

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
Greenville Downtown
Save 100% on your flight
Price was $1,415, price is now $1,065 per person
$1,065
per person
Nov 13 - Nov 17
found 16 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Greenville (GSP)
9.6/10 Exceptional! (376 reviews)
The staff at this facility are the best I’ve ever dealt with at a hotel. The room was very spacious and clean. Very impressed with the whole experience at the Grand Bohemian.

Reviewed on Aug 24, 2025

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast

4 out of 5
Price was $591, price is now $449 per person
$449
per person
Oct 9 - Oct 12
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
10/10 Exceptional! (68 reviews)
Wonderful experience all around! Breakfast was amazing each morning Host was attentive and friendly, going above and beyond to find out a little about us to make our stay extra special.

Reviewed on Aug 3, 2025

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Mayo Hotel Deals

ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

2 out of 5
490 W Blackstock Road, Spartanburg, SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $91 total per night from Aug 31 to Sep 1
$91 total
Aug 31 - Sep 1
Total with taxes and fees
8/10 Very Good! (212 reviews)
"The room was clean and in good condition. Early check-in resulted in being charged twice for the deposit. There was no roll-away bed as advertised. You will need to bring your own coffee maker, cooking utensils, and dinnerware for extended stay."

Reviewed on Aug 20, 2025

ECHO Suites Extended Stay by Wyndham Spartanburg
Spartanburg Marriott

Spartanburg Marriott

3.5 out of 5
299 North Church Street, Spartanburg, SC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $131 total per night from Sep 2 to Sep 3
$131 total
Sep 2 - Sep 3
Total with taxes and fees
Spartanburg Marriott
Days Inn by Wyndham Spartanburg Waccamaw

Days Inn by Wyndham Spartanburg Waccamaw

2 out of 5
101 Outlet Rd, Spartanburg, SC
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $65 total per night from Sep 5 to Sep 6
$65 total
Sep 5 - Sep 6
Total with taxes and fees
Days Inn by Wyndham Spartanburg Waccamaw
See all 405 properties in Mayo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Mayo vacation package cost?
Offering great value package deals from $289 on Expedia, you'll be surprised at how little a vacation to Mayo costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Mayo?
You can usually find lower prices and greater availability in December, January and February. Take a look at our cheap Mayo vacation packages and you could land some excellent off-season deals.
How many days is enough for Mayo?
Typically, a handful of days is enough to see the main attractions during your Mayo vacation. However, if you'd like to have time to relax or take day trips, think about extending your itinerary.
How to find the best Mayo package deals?
Begin your search for a Mayo package deal by entering your preferred trip dates and destination under our "Packages" tab. Then add a few filters, like "Popular locations" and "Amenities," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the perfect Mayo package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Mayo getaway off to a flying start.
Is it cheaper to book a Mayo vacation as a package?
You can enjoy significant savings on your next Mayo break by booking a personalized vacation package. Check the "Package" heading, then select your travel dates and destination to view the best flight and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Mayo?
If you've got your Mayo travel dates finalized, book as soon as you can to snap up some terrific deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment getaways? Our last-minute deals are great for traveling on a whim.
Does Expedia offer Book Now, Pay Later Mayo vacation packages?
If you're anything like us, you love traveling but are not a fan of the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the total cost of your Mayo trip across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.