Mayo Vacations from $634
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The Latest Mayo vacation packages
Price found within the past 48 hours. Click for updated prices.
Hotel Hartness
$643
per person
Nov 6 - Nov 9
found 12 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Greenville (GSP)
9.8/10 Exceptional! (817 reviews)
Absolutely fell in love with the grounds, room was beautiful and spacious. Breakfast was delightful. Can’t wait to return!
Reviewed on Aug 27, 2026
Mayo Hotel Deals
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
161 Sha Ln Spartanburg SC
Fully refundableReserve now, pay when you stay
$99 nightly
$110 total
Sep 20 - Sep 21
Total with taxes and fees
8.6/10 Excellent! (1,001 reviews)
"Over charged me for a clean fee"
Reviewed on Aug 27, 2026
Comfort Suites At WestGate Mall
458 West Blackstock Road Spartanburg SC
Fully refundable
$90 nightly
$100 total
Sep 20 - Sep 21
Total with taxes and fees
8.4/10 Very Good! (1,002 reviews)
"The room was clean staff was somewhat helpful and friendly"
Reviewed on Aug 27, 2026
AC Hotel by Marriott Spartanburg
225 West Main Street Spartanburg SC
Fully refundableReserve now, pay when you stay
$149 nightly
$165 total
Sep 6 - Sep 7
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Mayo Vacation Packages
Mayo Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Greenville-Spartanburg Intl. Airport (GSP) |
Population | 1,600 |
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Frequently asked questions
How much does a Mayo vacation package cost?
Offering great value package deals from $634 on Expedia, you'll be surprised at how little a vacation to Mayo costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Mayo?
You can usually find lower prices and greater availability in December, January and February. Take a look at our cheap Mayo vacation packages and you could land some excellent off-season deals.
How many days is enough for Mayo?
Typically, a handful of days is enough to see the main attractions during your Mayo vacation. However, if you'd like to have time to relax or take day trips, think about extending your itinerary.
How to find the best Mayo package deals?
Begin your search for a Mayo package deal by entering your preferred trip dates and destination under our "Packages" tab. Then add a few filters, like "Popular locations" and "Amenities," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the perfect Mayo package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Mayo getaway off to a flying start.
Is it cheaper to book a Mayo vacation as a package?
You can enjoy significant savings on your next Mayo break by booking a personalized vacation package. Check the "Package" heading, then select your travel dates and destination to view the best flight and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Mayo?
If you've got your Mayo travel dates finalized, book as soon as you can to snap up some terrific deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment getaways? Our last-minute deals are great for traveling on a whim.
Does Expedia offer Book Now, Pay Later Mayo vacation packages?
If you're anything like us, you love traveling but are not a fan of the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the total cost of your Mayo trip across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
