Mayo Vacations from $471

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The Latest Mayo vacation packages

Price found within the past 48 hours. Click for updated prices.
Hampton Inn Greenville I-385 - Woodruff Rd.

Hampton Inn Greenville I-385 - Woodruff Rd.

3 out of 5
Price was $565, price is now $471 per person
$471
per person
Jul 30 - Aug 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
8.8/10 Excellent! (835 reviews)
The bathroom had a horrible sewer smell. That was the problem the entire time.

Reviewed on May 24, 2026

Hotel Hartness

Hotel Hartness

4 out of 5
Price was $894, price is now $667 per person
$667
per person
Jul 30 - Aug 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
9.8/10 Exceptional! (721 reviews)
Clean room but the shower place had some shampoo on the ground

Reviewed on May 26, 2026

Hilton Greenville

Hilton Greenville

3.5 out of 5
Price was $605, price is now $479 per person
$479
per person
Jul 30 - Aug 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
8.2/10 Very Good! (1,004 reviews)
nothing wrong with this stay to the point to talk down on it , place is just a little dated . staff was helpful . you get what you pay for

Reviewed on May 25, 2026

Home2 Suites by Hilton Greenville Airport

Home2 Suites by Hilton Greenville Airport

3 out of 5
Price was $650, price is now $530 per person
$530
per person
Jul 30 - Aug 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
9.2/10 Wonderful! (397 reviews)
Clean hotel, lots of amenities. The staff was great. I’ll stay at Hilton again

Reviewed on Apr 26, 2026

Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek

4 out of 5
Price was $676, price is now $563 per person
$563
per person
Jul 30 - Aug 3
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Greenville (GSP)
No reviews
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Mayo Hotel Deals

Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

2.5 out of 5
501 South Blackstock Rd Spartanburg SC
Fully refundable
$59 nightly
The price is $66 total per night from Jun 28 to Jun 29
$66 total
Jun 28 - Jun 29
Total with taxes and fees
6/10 (610 reviews)
"I stayed for 4 days 5/20-5/24. Upon arrival, my sheets were dirty, as well as the countertops, windows and shower floor. I asked for a new room and was unable to switch due to being “overbooked”. The ice machine on the 2nd floor did not work so I had to keep doing to the lobby for ice. EVERY SINGLE ..."

Reviewed on May 26, 2026

Sleep Inn Spartanburg Southwest
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

2.5 out of 5
458 West Blackstock Road Spartanburg SC
Fully refundable
$91 nightly
The price is $101 total per night from Jun 21 to Jun 22
$101 total
Jun 21 - Jun 22
Total with taxes and fees
8.2/10 Very Good! (1,004 reviews)
"Hot breakfast food was cool on 3 of 6 mornings. Otherwise stay was excellent."

Reviewed on May 27, 2026

Comfort Suites At WestGate Mall
Best Western Spartanburg Northwest

Best Western Spartanburg Northwest

3 out of 5
110 Mobile Dr Spartanburg SC
$84 nightly
The price is $93 total per night from Jun 7 to Jun 8
$93 total
Jun 7 - Jun 8
Total with taxes and fees
8.4/10 Very Good! (907 reviews)
"Property is ok. Comfortable bed and clean room. Breakfast was good. Area around hotel is fair. Probably wouldn't stay again due to location."

Reviewed on May 27, 2026

Best Western Spartanburg Northwest
See all 485 properties in Mayo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mayo Vacation Packages

Mayo Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Greenville-Spartanburg Intl. Airport (GSP)
Population
1,600

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Frequently asked questions

How much does a Mayo vacation package cost?
Offering great value package deals from $471 on Expedia, you'll be surprised at how little a vacation to Mayo costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Mayo?
You can usually find lower prices and greater availability in December, January and February. Take a look at our cheap Mayo vacation packages and you could land some excellent off-season deals.
How many days is enough for Mayo?
Typically, a handful of days is enough to see the main attractions during your Mayo vacation. However, if you'd like to have time to relax or take day trips, think about extending your itinerary.
How to find the best Mayo package deals?
Begin your search for a Mayo package deal by entering your preferred trip dates and destination under our "Packages" tab. Then add a few filters, like "Popular locations" and "Amenities," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the perfect Mayo package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Mayo getaway off to a flying start.
Is it cheaper to book a Mayo vacation as a package?
You can enjoy significant savings on your next Mayo break by booking a personalized vacation package. Check the "Package" heading, then select your travel dates and destination to view the best flight and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Mayo?
If you've got your Mayo travel dates finalized, book as soon as you can to snap up some terrific deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment getaways? Our last-minute deals are great for traveling on a whim.
Does Expedia offer Book Now, Pay Later Mayo vacation packages?
If you're anything like us, you love traveling but are not a fan of the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the total cost of your Mayo trip across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.