Title: Mebane, NC Guest Houses from $148 | Expedia.com [Mebane Travel Guide](https://expedia.com/Mebane.dx180961)[Hotels in Mebane](https://expedia.com/Mebane-Hotels.d180961.Travel-Guide-Hotels)[Vacation Rentals in Mebane](https://expedia.com/Mebane-Vacation-Rentals.d180961.Travel-Guide-VacationRentals)[Flights to Mebane](https://expedia.com/Cheap-Flights-To-Mebane.d180961.Travel-Guide-Flights)[Car Rentals in Mebane](https://expedia.com/Car-Rentals-In-Mebane.d180961.Car-Rental-Guide)[Mebane Vacation Packages](https://expedia.com/Mebane.d180961.Destination-Travel-Guides) ![Farm surrounded by a harvested field](https://images.trvl-media.com/place/180961/5f702896-f7fc-45a7-9280-3872f62bf7f7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/180961/5f702896-f7fc-45a7-9280-3872f62bf7f7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check prices for these dates Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=180961&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=180961&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=180961&startDate=2026-04-24&endDate=2026-04-26&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=180961&startDate=2026-05-22&endDate=2026-05-24&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mebane guest houses ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89260000/89254700/89254655/93c3c36b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/90000000/89260000/89254700/89254655/6e386224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89260000/89254700/89254655/ffb55cb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89260000/89254700/89254655/44b4977c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Art, Beauty, Nature: A Woodland Retreat [](https://www.expedia.com/Chapel-Hill-Hotels-Art.h89254655.Hotel-Information) Chapel Hill 9.0/10 Wonderful (24 reviews) "Great stay! Will be staying again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ches S. $134 nightly $148 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Chapel-Hill-Hotels-Art.h89254655.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/103000000/102700000/102698300/102698297/b9002905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/103000000/102700000/102698300/102698297/55a4cb25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102700000/102698300/102698297/c80ab553.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102700000/102698300/102698297/fe520304.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tiny Home in the Bull City-Walk to Duke Hospital [](https://www.expedia.com/Raleigh-Hotels-Tiny-Home-In-The-Bull-City-Walk-To-Duke-Hospital.h102698297.Hotel-Information) Durham 9.6/10 Exceptional (5 reviews) "Had a relaxing, comfortable stay and highly recommend! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katie P. $251 nightly $284 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Tiny-Home-In-The-Bull-City-Walk-To-Duke-Hospital.h102698297.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08®ionId=180961&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMebane-Guest-Houses.d180961-aaGuestHouses.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMebane-Guest-Houses.d180961-aaGuestHouses.Travel-Guide-Accommodation) ## Top Mebane Hotel Reviews ![La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill](https://images.trvl-media.com/lodging/1000000/170000/165800/165760/adc70ef4_y.jpg) ### La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill 2/10 Terrible "The hotel is so outdated, everything is very old and run down. The rooms have almost no outlets, bad lighting. AC unit smells. The breakfast was the wrist part honestly!! No healthy options at all, microwaved eggs are so wet and gross, biscuits are frozen. That was basically what they serve. The WiFi is horrible!! Which funny enough is a member perk" [](https://expedia.com/Raleigh-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Univ-Area-Chapel-Hill.h165760.Hotel-Information) ![SpringHill Suites by Marriott Durham Chapel Hill](https://images.trvl-media.com/lodging/4000000/3530000/3525300/3525287/e14e80ea_y.jpg) ### SpringHill Suites by Marriott Durham Chapel Hill 10/10 Excellent "Clean and Spacious " [](https://expedia.com/Raleigh-Hotels-SpringHill-Suites-By-Marriott-Durham-Chapel-Hill.h3525287.Hotel-Information) ![Comfort Inn & Suites Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04_y.jpg) ### Comfort Inn & Suites Durham near Duke University 8/10 Good "It was normal overall but the business was down and I really needed it" [](https://expedia.com/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) ![University Inn Durham next to Duke University Medical Center](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/80e8b722_y.jpg) ### University Inn Durham next to Duke University Medical Center 10/10 Excellent "Large room, comfortable bed, kind staff, very clean. " [](https://expedia.com/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information) ![Hilton Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/18900/18821/aa0fe1f8_y.jpg) ### Hilton Durham near Duke University 6/10 Okay "It was ok. Way overpriced for what they gave you. Just a room and a bed. Nothing more. " [](https://expedia.com/Raleigh-Hotels-Hilton-Durham-Near-Duke-University.h18821.Hotel-Information) ![DoubleTree Suites by Hilton Raleigh - Durham](https://images.trvl-media.com/lodging/1000000/20000/13200/13139/w3840h2557x0y0-f360c06d_y.jpg) ### DoubleTree Suites by Hilton Raleigh - Durham 10/10 Excellent "Great place to stay with your family or just to get away from all the noise of life" [](https://expedia.com/Raleigh-Hotels-DoubleTree-Suites-By-Hilton-Raleigh-Durham.h13139.Hotel-Information) ![Courtyard Durham Near Duke University/Downtown](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/6d146009_y.jpg) ### Courtyard Durham Near Duke University/Downtown 10/10 Excellent "1 night stay was very pleasant. I’d stayed here before and felt very safe and comfortable both times. Didn’t get a chance to use the pool or hot tub; maybe next time." [](https://expedia.com/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) ![Candlewood Suites Durham by IHG](https://images.trvl-media.com/lodging/1000000/530000/528800/528739/ab636bce_y.jpg) ### Candlewood Suites Durham by IHG 10/10 Excellent "💟" [](https://expedia.com/Raleigh-Hotels-Candlewood-Suites-Durham.h528739.Hotel-Information) ![JB Duke Hotel](https://images.trvl-media.com/lodging/16000000/15940000/15936000/15935986/0914b52f_y.jpg) ### JB Duke Hotel 10/10 Excellent "room temperature is adjustable with cool and heat. Restaurant in Lobby for dinner is comfortable and good food with friendly service. we ate lunch downstairs at their hotel restaurant and enjoyed good service and a great hamburger " [](https://expedia.com/Raleigh-Hotels-JB-Duke-Hotel.h15935986.Hotel-Information) ## Find out more about Mebane ## Mebane Guest Houses information | Number of reviews | 24 | | ----------------- | -------------- | | Accommodation | 7 Guest Houses | | Lowest Price | $148 | | Highest Price | $284 | ## Frequently asked questions ### What is the nightly rate for a guest house in Mebane? ### What's the difference between a Mebane guest house and a B&B? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Tanger Outlet Center ](https://www.expedia.com/Tanger-Outlet-Center-Hotels.0-l6138732-0.Travel-Guide-Filter-Hotels) - [Hotels near Alamance Regional Medical Center Mebane ](https://www.expedia.com/Alamance-Regional-Medical-Center-Mebane-Hotels.0-l6138738-0.Travel-Guide-Filter-Hotels) - 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