Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Mesa Resorts & Hotels with Spas

See all 121 Hotels in Mesa
Windemere Hotel and Conference Center

Windemere Hotel and Conference Center

5750 E Main St, Mesa
3.0 out of 5.0
2.8 out of 5 (1,391 reviews)
Great outside areasRooms overlook nice landscape, breakfast was easy. Pool, spa and pool area is beautiful. Room in need of update. Area around the hotel is not good. Homeless people sleeping in the corners of hotel.
  May 8, 2017

$69

$69
Ramada Mesa-Mezona Hotel

Ramada Mesa-Mezona Hotel

250 W Main St, Mesa
2.5 out of 5.0
3.8 out of 5 (1,202 reviews)
Clean and comfortableWe had 2 rooms for 1 night---a king bed, and 2 queens. Property was clean; likewise the room. Location was good for central Mesa, and close enough to highways to satisfy us. Restaurants close by. Breakfast was kind of "thin", more "continental" than "full". Pool and spa were nice, well maintained. ...
 Paul May 19, 2014

$57

$57
Sheraton Mesa Hotel at Wrigleyville West

Sheraton Mesa Hotel at Wrigleyville West

860 N Riverview, Mesa
4.0 out of 5.0
4.5 out of 5 (373 reviews)
My stay in ArizonaThis hotel is great. It has everything you need. Pools, gym, restaurants, spa. And the park is in walking distance. It was a great visit
 shawn Oct 17, 2016

$119

$119
La Quinta Inn & Suites Phoenix Mesa West

La Quinta Inn & Suites Phoenix Mesa West

902 W Grove Ave, Mesa
3.0 out of 5.0
4.1 out of 5 (980 reviews)
Mesa Pleasure TripWe stayed at the La Quinta Inn in West Mesa for 3 nights. We enjoyed our stay. The hotel staff were very friendly and helpful. There were a few spots around the hotel that could have been cleaned up or repaired, but minor items. The outside pool and spa areas were clean and comfortable and provided ...
 Michael Oct 22, 2016

$89

$89
Best Western Legacy Inn & Suites

Best Western Legacy Inn & Suites

4470 South Power Road, Mesa
3.0 out of 5.0
4.2 out of 5 (1,121 reviews)
Better than expectedGreat outdoor spa and heated pool. Nice continental breakfast meal and seating area - opened up very early.
  Jan 15, 2016

$91

$91
Country Inn & Suites By Carlson, Mesa, AZ

Country Inn & Suites By Carlson, Mesa, AZ

6650 E Superstition Springs Blvd, Mesa
3.0 out of 5.0
4.1 out of 5 (651 reviews)
long weekend with friendsHad a problem with loud alarm coming from the next room for 2 nights. Hotel moved me to a suite. Nice.
  Dec 27, 2017

$118

$118
Dobson Ranch Inn and Suites

Dobson Ranch Inn and Suites

1666 S Dobson Road, Mesa
3.5 out of 5.0
3.3 out of 5 (2,184 reviews)
xxLoved the spa, but it wasn't always open at the posted times.restaurant bar tender was very nice & helpful....food was very good
 s Feb 4, 2014

$79

$79
Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa

1422 W Bass Pro Drive, Mesa
3.5 out of 5.0
4.7 out of 5 (1,337 reviews)
You know what you are getting with Hyatt Place2nd time staying in a Hyatt Place (Seattle was the other) with 2 kids (5 &2). rooms are big enough for kids to play. hotel had a nice pool/spa and putting green area for kids to play on. In a great location near shops and food and there is a terrific park just down the street. Kids get to pick what ...
 Ashley Jan 5, 2016

$118

$118
Baymont Inn & Suites Mesa Near Downtown

Baymont Inn & Suites Mesa Near Downtown

651 E Main St, Mesa
2.5 out of 5.0
4.2 out of 5 (922 reviews)
Very niceI went to Mesa for a short (3 day) stay. Baymont was in the neighborhood I needed to visit and had good reviews. Newer hotel; very clean. Would stay there again, and would recommend to anyone needing basic accommodations (i.e., without pool, sauna, etc.).
 ep Jan 11, 2015

$85

$85
Best Western Plus Mesa

Best Western Plus Mesa

1563 S Gilbert Rd, Mesa
3.0 out of 5.0
4.1 out of 5 (1,054 reviews)
It was good. The breakfast buffet was very good.
  Jan 12, 2018

$84

$84
Westgate Painted Mountain Golf Resort

Westgate Painted Mountain Golf Resort

6302 E Mckellips Rd, Mesa
4.5 out of 5.0
3.8 out of 5 (603 reviews)
Attractive on outside, butThis hotel is very attractive on the outside; grounds are well kept. However, the room was disappointing in that there was a very musky, stale odor probably from years of the room being used by smokers. Although there was no direct indication of this, everything I took with me smelled like stale ...
 Eve Jan 11, 2015

$109

$109
Phoenix Mesa Marriott

Phoenix Mesa Marriott

200 N Centennial Way, Mesa
4.0 out of 5.0
4.2 out of 5 (708 reviews)
A/C was not working in 108 degree weatherI reserved 3 rooms at this hotel because Expedia was offering a great deal. When we arrived on the day to check in it was 108 degrees outside. We walked into the lobby and it felt like a sauna. I was hoping it was just hot because the doors were open. When we arrived into our rooms it was unbearable. ...
  Jun 17, 2014

$109

$109
Holiday Inn Hotel & Suites Phoenix - Mesa / Chandler

Holiday Inn Hotel & Suites Phoenix - Mesa / Chandler

1600 S Country Club Dr, Mesa
3.5 out of 5.0
3.8 out of 5 (505 reviews)
AwesomeThis hotel was one of the best we stayed at. Pillow top beds, nice and clean. Also has a nice restaurant and bar. Beautiful pool and hot tub!!!!!!! Will definitely stay here again
  Jan 12, 2018

$117

$117
GreenTree Inn & Suites Mesa

GreenTree Inn & Suites Mesa

1405 S Westwood, Mesa
3.0 out of 5.0
4.2 out of 5 (442 reviews)
Clean rooms with helpful and friendly staff. It was exactly as advertised.
  Jan 16, 2018

$74

$74
Econo Lodge Inn & Suites

Econo Lodge Inn & Suites

951 W Main St, Mesa
2.5 out of 5.0
3.7 out of 5 (1,009 reviews)
The hotel staff was great I needed help finding the ward my uncle's funeral was going to be. The lady behind the desk knew exactly where Pueblo St was, and wrote it down for me. We drove there with no problem. It was wonderful.The staff was
  Jan 6, 2018

$53

$53
Best Western Superstition Springs Inn

Best Western Superstition Springs Inn

1342 S Power Road, Mesa
3.0 out of 5.0
3.8 out of 5 (192 reviews)
Good central locationStayed here while attending several square dances in the area. Great room and professional desk service.
  Jan 10, 2018

$85

$85
Courtyard by Marriott Phoenix Mesa

Courtyard by Marriott Phoenix Mesa

1221 S Westwood, Mesa
3.5 out of 5.0
4.4 out of 5 (497 reviews)
Convenient for shopping, diningIt was comfortable and quiet. I was lucky enough to have the spa right outside my door and I took advantage of that.
  Dec 28, 2015

$95

$95
Courtyard Phoenix Mesa Gateway Airport

Courtyard Phoenix Mesa Gateway Airport

6907 East Ray Road, Mesa
3.5 out of 5.0
4.7 out of 5 (162 reviews)
Friendly StaffWonderful, friendly staff!!! We loved the large private areas of the lobby and the secluded patio with so many different seating areas. It always smelled fresh in the Hotel whether it was in the lobby, hall ways or your room. Absolutely NO complaints.
 Lori Jan 2, 2016

$118

$118
La Quinta Inn & Suites Mesa Superstition Springs

La Quinta Inn & Suites Mesa Superstition Springs

6530 E Superstition Springs Blvd, Mesa
3.0 out of 5.0
4.3 out of 5 (771 reviews)
Nice place, close to everything in MesaGreat facility; nice pool and spa, pleasant staff, new fictures. Good rate for our five night stay.
 Elizabeth Dec 9, 2014

$119

$119
Residence Inn Phoenix Mesa

Residence Inn Phoenix Mesa

941 W Grove Ave, Mesa
3.5 out of 5.0
4.3 out of 5 (256 reviews)
Very nice and comfyExcellent!! Spacious room, nice blackout window coverings, very nice & balanced motif Love it 😍
  Dec 23, 2017

$143

$143
Map

Recently booked Resorts & Hotels with Spas in Mesa

Red Roof Inn Mesa
2.5 out of 5.0
Last booking: 1 minute ago
Hyatt Place Phoenix/Mesa
3.5 out of 5.0
Last booking: 24 minutes ago
Best Western Plus Mesa
3.0 out of 5.0
Last booking: 27 minutes ago
Knights Inn Mesa Az
2.0 out of 5.0
Last booking: 43 minutes ago
Econo Lodge Inn & Suites
2.5 out of 5.0
Last booking: 49 minutes ago
Days Hotel Mesa Near Phoenix
3.0 out of 5.0
Last booking: 58 minutes ago
Motel 6 Mesa South
2.0 out of 5.0
Last booking: 1 hour ago
Four Points By Sheraton At Phoenix Mesa Gateway Airport
3.5 out of 5.0
Last booking: 1 hour ago
Mesa Travelodge
2.5 out of 5.0
Last booking: 2 hours ago

Mesa Resorts & Spa Travel Guide

Indulge Yourself with a Mesa Spa Vacation

Grab your bag and leave behind worries to begin your pressure-free vacation. If you are looking for high-end hotel or reasonable options, we can help you find the ideal location to stay. You'll find in urging you to take it easy. There is no treatment like spa treatment. Take the opportunity for a trip where you can leave all your stresses behind in Mesa.

We Have Divine Spa Deals in Mesa

Make sure to take your time once you've checked-in. You've just begun your vacation, so spend a little time getting acquainted with your room. Decompress and stretch out for a bit. After that you can book your first appointment to indulge yourself at a nearby spa. After you've spent the afternoon enjoying a massage, relaxing within the steam room, or lounging by the pool, you can put on your explorer's hat and start uncovering the hidden gems of Mesa. Discovering incredible foods, curio shops, or an intriguing museum can be one of the many highlights of your trip. If you're not sure where to begin, talk to your hotel's front-desk attendant to get a feel for what Mesa has to offer. There is no better source than a local to point you to an exciting evening out or to a cafe to sip a few cocktails at and mingle. Wherever you decide to go, just be sure to take it easy. Your spa trip should be nothing but exceedingly relaxing.

With so many ways to wind you down, Mesa continually ranks as one of the best spots for a spa vacation.