Find hotels in Mesice from $45

Start date: Check-in selected.
To Date
End date: Check-out
  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mesice hotels

Holiday Inn Prague Airport by IHG

Holiday Inn Prague Airport by IHG
4.0 star property
Prague 6
8.8 out of 10, Excellent, (1001)
"The room was clean and breakfast was good "
United States
Kest
$90 nightly
The price is $105
Jan 25 - Jan 26, 2026
Total with taxes and fees
Holiday Inn Prague Airport by IHG

Dvůr Hoffmeister

Dvůr Hoffmeister
3.0 star property
Cicovice
9.6 out of 10, Exceptional, (91)
"The lovely bathroom and jet tub Place was pretty nice and away from the busy tourist areas "
United States
Natisha
$83 nightly
The price is $93
Jan 8 - Jan 9, 2026
Total with taxes and fees
Dvůr Hoffmeister

Hotel Adalbert

Hotel Adalbert
3.0 star property
Prague 6
9.2 out of 10, Wonderful, (532)
"A very unique and affordable stay at a monastery! Quiet and far from the center of Prague, but there is easy access to public transport just across the street."
United States
Anastasia
$75 nightly
The price is $89
Jan 8 - Jan 9, 2026
Total with taxes and fees
Hotel Adalbert

SKY Hotel Prague

SKY Hotel Prague
3.5 star property
Prague 6
8.6 out of 10, Excellent, (581)
"Very clean, comfortable. Well-lit with good locations of lights. The bed was comfortable and linens were great. There is a nice coffee machine in the lobby that makes espresso. Nice gentleman helped us with accessing our room. I really recommend this hotel and we enjoyed the visit, staying two extra nights."
United States
Lisa
$97 nightly
The price is $113
Jan 17 - Jan 18, 2026
Total with taxes and fees
SKY Hotel Prague

Courtyard by Marriott Prague Airport

Courtyard by Marriott Prague Airport
4.0 star property
Prague 6
9.2 out of 10, Wonderful, (1001)
"Fantastic stay experience "
Canada
Yitao
$150 nightly
The price is $173
Jan 18 - Jan 19, 2026
Total with taxes and fees
Courtyard by Marriott Prague Airport

Majestic Plaza Hotel Prague

Majestic Plaza Hotel Prague
4.5 star property
Prague City Center
9.0 out of 10, Wonderful, (1088)
"Clean room, friendly staff, lovely balcony."
United Kingdom
Jude
$68 nightly
The price is $82
Jan 20 - Jan 21, 2026
Total with taxes and fees
Majestic Plaza Hotel Prague

Hotel Golf Prague

Hotel Golf Prague
4.0 star property
Prague 5
8.8 out of 10, Excellent, (639)
"Staff were okay, the hotel is very clean, and breakfast was great!!! All fresh foods!! I wish parking was a bit cheaper though. I would definitely recommend "
United States
Philomena
$60 nightly
The price is $73
Jan 11 - Jan 12, 2026
Total with taxes and fees
Hotel Golf Prague

Vienna House by Wyndham Diplomat Prague

Vienna House by Wyndham Diplomat Prague
4.5 star property
Prague 6
9.2 out of 10, Wonderful, (571)
"Great hotel. We have stayed here often when we are in Prague. "
United States
jim
$83 nightly
The price is $98
Jan 18 - Jan 19, 2026
Total with taxes and fees
Vienna House by Wyndham Diplomat Prague

Michelangelo Grand Hotel Prague

Michelangelo Grand Hotel Prague
5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (3154)
"Great room, comfy bed, great breakfast, location excellent "
United Kingdom
Carol
$108 nightly
The price is $126
Jan 18 - Jan 19, 2026
Total with taxes and fees
Michelangelo Grand Hotel Prague

Iron Gate Hotel & Suites Prague by BHG

Iron Gate Hotel & Suites Prague by BHG
5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1001)
"Beautiful rustic hotel in an excellent location"
United States
Paula
$89 nightly
The price is $104
Jan 18 - Jan 19, 2026
Total with taxes and fees
Iron Gate Hotel & Suites Prague by BHG

Hilton Prague

Hilton Prague
5.0 star property
Karlín
8.4 out of 10, Very Good, (1004)
"Very excellent Hotel would recommend to anyone!"
Canada
Damien
$78 nightly
The price is $92
Jan 11 - Jan 12, 2026
Total with taxes and fees
Hilton Prague

Art Nouveau Palace Hotel

Art Nouveau Palace Hotel
5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (1005)
"Excellent hotel with friendly staff, great decor and convenient. Highly recommend this hotel."
United Kingdom
John
$81 nightly
The price is $96
Jan 11 - Jan 12, 2026
Total with taxes and fees
Art Nouveau Palace Hotel

Aurea Legends by Eurostars Hotel Company

Aurea Legends by Eurostars Hotel Company
4.0 star property
Prague City Center
9.8 out of 10, Exceptional, (185)
"Great Hotel"
Canada
Yitao
$73 nightly
The price is $86
Jan 7 - Jan 8, 2026
Total with taxes and fees
Aurea Legends by Eurostars Hotel Company

Mosaic House Design Hotel

Mosaic House Design Hotel
4.0 star property
Nové Město
9.8 out of 10, Exceptional, (721)
"Breakfast is very good, nice staffs"
Hong Kong SAR China
Wilson
$63 nightly
The price is $75
Jan 18 - Jan 19, 2026
Total with taxes and fees
Mosaic House Design Hotel

Cosmopolitan Hotel Prague

Cosmopolitan Hotel Prague
5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (1067)
"Great location and fantastic hotel "
United Kingdom
David
$123 nightly
The price is $143
Jan 11 - Jan 12, 2026
Total with taxes and fees
Cosmopolitan Hotel Prague

Unitas Residence

Unitas Residence
3.0 star property
Prague City Center
9.4 out of 10, Exceptional, (496)
"Great location, helpful staff, excellent breakfast "
United Kingdom
Horace
$49 nightly
The price is $60
Jan 13 - Jan 14, 2026
Total with taxes and fees
Unitas Residence

Charles Bridge Palace

Charles Bridge Palace
4.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1004)
"We enjoyed our stay! The staff were wonderful and the location was amazing."
Australia
Robert
$62 nightly
The price is $74
Jan 15 - Jan 16, 2026
Total with taxes and fees
Charles Bridge Palace

Grandium Hotel Prague

Grandium Hotel Prague
5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1103)
"Great rooms, friendly staff, wonderful breakfast"
United States
Toni
$89 nightly
The price is $105
Jan 25 - Jan 26, 2026
Total with taxes and fees
Grandium Hotel Prague

Grand Hotel Prague Towers

Grand Hotel Prague Towers
5.0 star property
Prague 4
8.4 out of 10, Very Good, (1001)
"Clean , Christmas decorations, helpful friendly staff "
United States
Gemma
$82 nightly
The price is $92
Jan 11 - Jan 12, 2026
Total with taxes and fees
Grand Hotel Prague Towers

Hotel Exe City Park

Hotel Exe City Park
3.0 star property
Prague City Center
9.0 out of 10, Wonderful, (1001)
"Friendly staff, large room, big comfy bed, decent location. The only let down was the breakfast selection was small"
United Kingdom
Stephanie
$52 nightly
The price is $63
Jan 25 - Jan 26, 2026
Total with taxes and fees
Hotel Exe City Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Mesice Hotel Reviews

More cheap stays in Mesice

Hotels in Mesice with star-rating

Frequently asked questions

What is the best area to stay in Mesice?
The best area to stay in Mesice is near the town center, particularly around Kostel Narozeni Panny Marie (Church of the Nativity of the Virgin Mary).

This central area offers convenient access to local amenities and the town's main landmarks. You'll find a selection of local shops and eateries within walking distance. The area around the church provides a central point for exploring Mesice on foot.

For couples seeking a quiet retreat, staying within a short walk of the town center provides a relaxed setting while still being close enough to enjoy local dining and strolls.
When is the best time to go to Mesice?
The best time to visit Mesice is during the late spring and early autumn months, specifically from May to June and September to October. These periods offer pleasant weather conditions ideal for exploring the region.

During late spring, the countryside around Mesice is lush and green, with comfortable temperatures great for outdoor activities like hiking or visiting local vineyards. The days are long, allowing for extended sightseeing without the peak summer crowds.

Early autumn brings mild temperatures and the beautiful colors of changing foliage, making it a picturesque time for walks and enjoying the local harvest festivals.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mesice.
How can I save on a Mesice hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Mesice hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Mesice hotel?
Prices for hotels in Mesice often vary, but you can find a great deal from $45 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia