Historic Fort Selden, built in the Mesilla Valley, was a United States Army post occupying the area in what is now Radium Springs, New Mexico and was the site of a Confederate Army camp in 1861.

Mesilla Vacation Rentals

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Our top choices for Mesilla vacation rentals

Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
Mesilla
10.0 out of 10, Exceptional, (90 reviews)
"We loved everything…the amenities, decor, location, and host. It was a wonderful alternative to corporate hotels. Mesilla is such a charming and friendly community. We hope to stay there again someday."
United States
Melody
$198 nightly
The price is $223
Jun 15 - Jun 16
Total with taxes and fees
Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

4014/Russ Modern · New Home in Quiet Neighborhood - Relax and Enjoy

4014/Russ Modern · New Home in Quiet Neighborhood - Relax and Enjoy
Las Cruces
9.6 out of 10, Exceptional, (13 reviews)
"We really enjoyed staying here. It was clean, the furnishings were really nice, the location was great and the hosts were excellent. We would stay here again."
United States
Marc R.
$294 nightly
The price is $315
Jun 16 - Jun 17
Total with taxes and fees
4014/Russ Modern · New Home in Quiet Neighborhood - Relax and Enjoy

Charming 2 bedroom retreat at the end of the street equipped for any length stay

Charming 2 bedroom retreat at the end of the street equipped for any length stay
Las Cruces
10.0 out of 10, Exceptional, (11 reviews)
"Great condition"
United States
Angela E.
$182 nightly
The price is $208
Jun 17 - Jun 18
Total with taxes and fees
Charming 2 bedroom retreat at the end of the street equipped for any length stay

Southwest Gem just minutes from White Sands National Park

Southwest Gem just minutes from White Sands National Park
Las Cruces
10.0 out of 10, Exceptional, (29 reviews)
"Great place to stay visiting Las Cruces. "
United States
Mel K.
$253 nightly
The price is $269
Jun 14 - Jun 15
Total with taxes and fees
Southwest Gem just minutes from White Sands National Park

Tuscan Villa Outdoor Living, Jacuzzi & Gym

Tuscan Villa Outdoor Living, Jacuzzi & Gym
Las Cruces
9.2 out of 10, Wonderful, (20 reviews)
"Beautiful house and would stay again."
United States
Alethea S.
$256 nightly
The price is $277
Jun 17 - Jun 18
Total with taxes and fees
Tuscan Villa Outdoor Living, Jacuzzi & Gym

2 bd/2bth near NMSU and Memorial Medical Center

2 bd/2bth near NMSU and Memorial Medical Center
Las Cruces
10.0 out of 10, Exceptional, (3 reviews)
"It was strategically located for the event we attended."
United States
Gregory B.
$246 nightly
The price is $276
Jun 15 - Jun 16
Total with taxes and fees
2 bd/2bth near NMSU and Memorial Medical Center

Studio w/queen bed, pets ok, 3 min to Farmer's mkt

Studio w/queen bed, pets ok, 3 min to Farmer's mkt
Las Cruces
10.0 out of 10, Exceptional, (2 reviews)
"Wonderful property. Peace and quiet. Lots of wildlife. Worth the unpaved road to reach the property."
United States
Robert T.
$173 nightly
The price is $194
Jun 25 - Jun 26
Total with taxes and fees
Studio w/queen bed, pets ok, 3 min to Farmer's mkt

Charming 2-bedroom Casita In Mesilla Park

Charming 2-bedroom Casita In Mesilla Park
Las Cruces
9.8 out of 10, Exceptional, (8 reviews)
"Amazing place. Perfect for our stay! "
United States
Douglas N.
$157 nightly
The price is $170
Jun 15 - Jun 16
Total with taxes and fees
Charming 2-bedroom Casita In Mesilla Park

Modern Accessorized 3-Bedroom

Modern Accessorized 3-Bedroom
Las Cruces
9.0 out of 10, Wonderful, (29 reviews)
"Clean and close to everything…"
United States
Kathy & Mike k.
$270 nightly
The price is $293
Jun 16 - Jun 17
Total with taxes and fees
Modern Accessorized 3-Bedroom

Las Cruces Home w/ Fenced Yard: Recently Remodeled

Las Cruces Home w/ Fenced Yard: Recently Remodeled
3.0 star property
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"The host was thoughful. He provided all the information we needed and responded our questions really quickly. The house was clean and very well organized. This house had the best view at night. We will definitely visit again when we go Santa fe. 😊 "
United States
Nam
$247 nightly
The price is $283
Jun 11 - Jun 12
Total with taxes and fees
Las Cruces Home w/ Fenced Yard: Recently Remodeled

4098/Lyle SW · Brand New Home in Beautiful Golf Course Community

4098/Lyle SW · Brand New Home in Beautiful Golf Course Community
Las Cruces
10.0 out of 10, Exceptional, (15 reviews)
"Great location, nice kitchen and modern home!"
United States
Lindsey T.
$300 nightly
The price is $321
Jun 15 - Jun 16
Total with taxes and fees
4098/Lyle SW · Brand New Home in Beautiful Golf Course Community

Comfy SW Home with Private Yard & Mountain Views!

Comfy SW Home with Private Yard & Mountain Views!
Las Cruces
10.0 out of 10, Exceptional, (25 reviews)
"Very nice home, it was really nice for our family."
United States
Paul L.
$337 nightly
The price is $383
Jun 23 - Jun 24
Total with taxes and fees
Comfy SW Home with Private Yard & Mountain Views!

4086/Lyle Modern · Brand New Luxury Home in Golf Course Community

4086/Lyle Modern · Brand New Luxury Home in Golf Course Community
Las Cruces
10.0 out of 10, Exceptional, (9 reviews)
"Perfect house! "
United States
Rodney K.
$345 nightly
The price is $370
Jun 16 - Jun 17
Total with taxes and fees
4086/Lyle Modern · Brand New Luxury Home in Golf Course Community

Casa Del Sol - Peaceful Retreat In Beautiful Mesilla.

Casa Del Sol - Peaceful Retreat In Beautiful Mesilla.
Mesilla
9.8 out of 10, Exceptional, (32 reviews)
"Great location! "
United States
Marty
$151 nightly
The price is $153
Jul 6 - Jul 7
Total with taxes and fees
Casa Del Sol - Peaceful Retreat In Beautiful Mesilla.

Yucca House | Views, Jetted Bath, Central Retreat

Yucca House | Views, Jetted Bath, Central Retreat
Las Cruces
9.8 out of 10, Exceptional, (42 reviews)
"Very comfortable accommodations in a nice part of town, conveniently located off a main street. "
United States
Paul B.
$295 nightly
The price is $335
Jun 14 - Jun 15
Total with taxes and fees
Yucca House | Views, Jetted Bath, Central Retreat

Casa Sonoma | Spacious, Central Retreat | Peloton

Casa Sonoma | Spacious, Central Retreat | Peloton
Las Cruces
10.0 out of 10, Exceptional, (50 reviews)
"Beautiful place! Definitely will stay there again!!"
United States
Greg G.
$298 nightly
The price is $339
Jun 14 - Jun 15
Total with taxes and fees
Casa Sonoma | Spacious, Central Retreat | Peloton

Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces

Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces
Las Cruces
9.4 out of 10, Exceptional, (12 reviews)
"Great property and host - I wish we had reasons to return to Las Cruces!"
United States
Lori L.
$143 nightly
The price is $155
Jun 21 - Jun 22
Total with taxes and fees
Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces

Beautiful and comfortable two bedroom apartment

Beautiful and comfortable two bedroom apartment
Las Cruces
8.0 out of 10, Very Good, (4 reviews)
"We loved the location, really easy to get to the university and the shopping areas. Great place for our family to meet and gather! We were very pleased with the location. "
United States
tyra R.
$233 nightly
The price is $248
Jun 17 - Jun 18
Total with taxes and fees
Beautiful and comfortable two bedroom apartment

The Ritz serene spa sanctuary hot tub, mountain view, patio for the whole family

The Ritz serene spa sanctuary hot tub, mountain view, patio for the whole family
Las Cruces
9.6 out of 10, Exceptional, (48 reviews)
"Everything was as advertised, enjoyed our stay."
United States
Ashley M.
$187 nightly
The price is $202
Jun 16 - Jun 17
Total with taxes and fees
The Ritz serene spa sanctuary hot tub, mountain view, patio for the whole family

New Casita/Suite No cleaning fee.

New Casita/Suite No cleaning fee.
Las Cruces
9.6 out of 10, Exceptional, (39 reviews)
"Casita was just perfect for our two night stay in Las Cruces. "
United States
Ann
$128 nightly
The price is $139
Jun 16 - Jun 17
Total with taxes and fees
New Casita/Suite No cleaning fee.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesilla Hotel Reviews

Find out more about Mesilla

Everything you need to know about Mesilla vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesilla vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesilla vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Mesilla vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mesilla. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Mesilla in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $139 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Mesilla rentals

At Expedia, we put the best Mesilla vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Mesilla rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesilla vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesilla. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in Mesilla?

Yes, we give you a choice of vacation rentals near top attractions in Mesilla, or you can go with a more remote option if you're looking for relaxation. Mesilla is known for its restaurants and shopping. Make sure you have time to check out the theaters while you're in the area.

What are some of the best vacation rentals in Mesilla?

Casita Azul, Mesilla Plaza Only Steps Away: This highly rated vacation home rental in Mesilla is located on a lake and has a patio, a barbecue grill, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. You and your friends and family can relax into your vacation with amenities like a selection of books. Our travelers also rate Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian as a favorite home for rent in Mesilla.

How many vacation rentals will I find in Mesilla?

With 8 Expedia vacation rentals, you're sure to find just the right place for your Mesilla stay.

What’s there to see and do in Mesilla?

Cultural attractions include Fountain Theatre and Fountain Theater, whereas Rio Grande is one spot to enjoy nature. Other places in town to visit include Mesillia Plaza and San Albino Basilica.

What’s a vacation rental in Mesilla like?

Vacation rentals are privately owned properties you can stay in for short or long periods in Mesilla. Vacation rentals offer extras like laundry facilities and kitchens so you'll have a home away from home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of seclusion away from public hotel elevators and busy front desks while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive choice for a small group gathering.