Mission District Vacations from $274
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Your Mission District Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Mission District vacation package. However you picture yourself spending your days here, you'll find countless opportunities for fun, relaxation and adventure. Can't wait to get out and see the sights during your trip to Mission District? Be sure to check out nearby attractions like Lombard Street, University of San Francisco and University of California, San Francisco. Expedia is here to put your plans into action. Book your perfect Mission District vacation now.
The Latest Mission District Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Bay Landing San Francisco Airport Hotel
Save 100% on your flight
Price was $519, price is now $274 per person
$274
per person
Nov 3 - Nov 7
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9/10 Wonderful! (4,487 reviews)
Nice view, good restaurant's comfy bed
Reviewed on Aug 26, 2025
Fitzgerald Hotel
Union Square
Price was $1,023, price is now $508 per person
$508
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
7.8/10 Good! (438 reviews)
Staff is so polite and very helpful. The beds were firm-great for anyone who has a challenged back. Elevator is vintage and really neat but, not made for modern luggage and wheelchairs. Super clean-I always check! Lovely, convenient stay.
Reviewed on Aug 4, 2025
Nob Hill Hotel
Downtown San Francisco
Save 100% on your flight
Price was $1,315, price is now $739 per person
$739
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
7.8/10 Good! (1,003 reviews)
Great place, except when you walk out the door.
Reviewed on Aug 11, 2025
Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Save 100% on your flight
Price was $560, price is now $325 per person
$325
per person
Nov 3 - Nov 7
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9/10 Wonderful! (6,695 reviews)
Excellent choices for breakfast and despite being super busy, staff very helpful and well organised. Rooms well presented and clean.
WiFi connection was weak.
Reviewed on Aug 26, 2025
Pacific Heights Inn
Cow Hollow
Save 100% on your flight
Price was $672, price is now $400 per person
$400
per person
Oct 27 - Nov 3
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to San Francisco (SFO)
7.6/10 Good! (798 reviews)
Great place to have a stay when arriving late to CR or coming back. We arrived in CR at 6 pm and I just wanted a good nights sleep which they delivered. My only suggestion for these folks is update their TV’s. We were in isolated corners of CR and still had access to our Netflix which was a nice comfort at the end of the day.
Reviewed on Aug 15, 2025
Where to stay in Mission District
Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Fisherman's Wharf
1 out of top 10 points of interest in this area
4/5(38 area reviews)
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
Mission District Hotel Deals
Hotel Riu Plaza Fisherman's Wharf
2500 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $168 total per night from Aug 27 to Aug 28
$168 total
Aug 27 - Aug 28
Total with taxes and fees
8.8/10 Excellent! (6,695 reviews)
"It was great. Just"
Reviewed on Aug 23, 2025
Hyatt Regency San Francisco
5 Embarcadero Center, San Francisco, CA
Fully refundableReserve now, pay when you stay
$201 nightly
The price is $237 total per night from Aug 28 to Aug 29
$237 total
Aug 28 - Aug 29
Total with taxes and fees
9.2/10 Wonderful! (1,821 reviews)
"It was a great place to stay by the waterfront!"
Reviewed on Aug 25, 2025
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave, San Francisco, CA
Fully refundable
$131 nightly
The price is $154 total per night from Sep 2 to Sep 3
$154 total
Sep 2 - Sep 3
Total with taxes and fees
8.8/10 Excellent! (4,462 reviews)
Hefty deposit lovely stay
"Our room was clean and comfortable. My only complaint is that when I checked in, I was asked to make a $500 deposit...this feels excessive. I've only ever made a $100 deposit for a hotel room at most, and I felt very blindsided by this price and request as I didn't see any information about it prior. ..."
Reviewed on Aug 25, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Mission District
Mission Dolores Park
Great views of downtown San Francisco, tree-shaded lawns and a children’s playground await at this popular hillside park in the vibrant Mission District.
San Francisco Public Library
After visiting San Francisco Public Library, make a plan to see the other sights and activities in San Francisco. Discover the acclaimed theater scene and shops in this vibrant area.
Balmy Alley
Balmy Alley is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed theater scene in this vibrant area.
Things to do
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- San Francisco Vacations
- Hua Zang Si
- Marsh Theater
- Mission Dolores Park
- SF Armory
- Mission San Francisco de Asís
- Galería de la Raza
- Castro Street
- 22nd St Hill
- Visit Downtown San Francisco
- Fouladi Projects
- San Francisco City Hall
- U.S. Mint
- Visit Mission Dolores
- Castro Theatre
- Harvey Milk Plaza
- San Francisco Zen Center
- Louise Davies Symphony Hall
- Noe Valley Vacations
- The Promenade
- Bill Graham Civic Auditorium
- Randall Museum
- Nobby Clarke Mansion
- Visit Castro District
- Randall Junior Museum
- Golden Gate Model Railroad Club
- Mission Creek Park
- Corona Heights Park
- War Memorial Opera House
- Orpheum Theatre
- Civic Center Plaza
- Vulcan Steps
- McLellan Botanicals
- Painted Ladies
- San Francisco Federal Building
- Kite Hill Open Space
- Asian Art Museum of San Francisco
- United Nations Plaza
- California State Building
- Alamo Square
- Haight Street
- Chase Center
- Van Ness Avenue
- Visit Bernal Heights
- Twin Peaks
- Academy of Art University
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.