Mission District Vacations from $256
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Your Mission District Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Mission District vacation package. However you picture yourself spending your days here, you'll find countless opportunities for fun, relaxation and adventure. Can't wait to get out and see the sights during your trip to Mission District? Be sure to check out nearby attractions like Lombard Street, University of San Francisco and University of California, San Francisco. Expedia is here to put your plans into action. Book your perfect Mission District vacation now.
The Latest Mission District Vacation Packages
Montage Healdsburg
Reviewed on Nov 30, 2025
Treehouse Hotel Silicon Valley
Reviewed on Nov 23, 2025
Hotel Riu Plaza Fisherman's Wharf
Reviewed on Dec 6, 2025
Where to stay in Mission District
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Mission District Hotel Deals
Holiday Inn Golden Gateway by IHG
Clean room, courteous staff, walking distance to lots of eateries.
Reviewed on Dec 4, 2025
Hotel Riu Plaza Fisherman's Wharf
The room and hotel was clean. The staff was friendly. The hotel was a great location. Couldn’t ask for anything else.
Reviewed on Dec 5, 2025
DoubleTree by Hilton Hotel Berkeley Marina
Excellent breakfast
Reviewed on Dec 3, 2025
Discover the most popular places to visit in Mission District
Mission Dolores Park
Great views of downtown San Francisco, tree-shaded lawns and a children’s playground await at this popular hillside park in the vibrant Mission District.
Mission San Francisco de Asís
Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the notable monuments and shops in this vibrant area.
San Francisco Public Library
After visiting San Francisco Public Library, make a plan to see the other sights and activities in San Francisco. Discover the acclaimed theater scene and notable monuments in this vibrant area.
Things to do
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise (2-hours)
Alcatraz Island Ticket and Hop-on Hop-Off Bus Tour
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- San Francisco Vacations
- Hua Zang Si
- Marsh Theater
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- SF Armory
- Mission San Francisco de Asís
- Galería de la Raza
- Castro Street
- 22nd St Hill
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- San Francisco Federal Building
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- United Nations Plaza
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- Alamo Square
- Haight Street
- Chase Center
- Van Ness Avenue
- Visit Bernal Heights
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- Academy of Art University