Mission District Vacations
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Your Mission District Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Mission District vacation package. However you picture yourself spending your days here, you'll find countless opportunities for fun, relaxation and adventure. Can't wait to get out and see the sights during your trip to Mission District? Be sure to check out nearby attractions like Lombard Street, University of San Francisco and University of California, San Francisco. Expedia is here to put your plans into action. Book your perfect Mission District vacation now.
Price found within the past 48 hours. Click for updated prices.
- Stanford Court San Francisco
Aug 7 - Aug 10Stanford Court San Francisco + Flight
Downtown San Francisco3 nights9.0/10 - Wonderful (1,402 reviews)"Great place!"Reviewed May 28, 2026Roundtrip • San Diego (SAN) - San Francisco (SFO)SAN - SFO • Nonstop SFO - SAN • Nonstop - 1 Hotel San Francisco
Aug 23 - Aug 281 Hotel San Francisco + Flight
Downtown San Francisco5 nights9.2/10 - Wonderful (555 reviews)"top-notch could notask for anything better, love the bikes! If they could add a infinity pool, that would be awesome"Reviewed May 25, 2026Roundtrip • Dallas (DFW) - San Francisco (SFO)DFW - SFO • Nonstop SFO - DFW • Nonstop - Hotel Riu Plaza Fisherman's Wharf
Aug 7 - Aug 10Hotel Riu Plaza Fisherman's Wharf + Flight
Fisherman's Wharf3 nights9.0/10 - Wonderful (7,487 reviews)"Nothing"Reviewed May 30, 2026Roundtrip • San Diego (SAN) - San Francisco (SFO)SAN - SFO • Nonstop SFO - SAN • Nonstop - Treehouse Hotel Silicon Valley
Jul 31 - Aug 3Treehouse Hotel Silicon Valley + Flight
Sunnyvale3 nights9.6/10 - Exceptional (98 reviews)"Amazing property ! Highly recommend . No ice Machine which was different, but overall the stay was nice"Reviewed May 26, 2026Roundtrip • San Diego (SAN) - San Francisco (SFO)SAN - SFO • Nonstop SFO - SAN • Nonstop - The Huntington Hotel
Jul 3 - Jul 7The Huntington Hotel + Flight
Downtown San Francisco4 nights9.0/10 - Wonderful (18 reviews)Roundtrip • Dallas (DFW) - San Francisco (SFO)DFW - SFO • 1 stop SFO - DFW • 1 stop
Where to stay in Mission District
Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Union Square
4/5(5,227 area reviews)
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Mission District Hotel Deals
Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $230 total per night from Jun 8 to Jun 9
$230 total
Jun 8 - Jun 9
Total with taxes and fees
9/10 Wonderful! (7,487 reviews)
"The room was very clean and spacious. We had everything we needed. The breakfast buffet was amazing. So many choices. Our stay was perfect!"
Reviewed on May 30, 2026
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundable
$152 nightly
The price is $179 total per night from May 31 to Jun 1
$179 total
May 31 - Jun 1
Total with taxes and fees
9/10 Wonderful! (5,818 reviews)
"One of My favorite I love it thank you very nice place"
Reviewed on May 29, 2026
Hilton San Francisco Union Square
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $189 total per night from Jun 5 to Jun 6
$189 total
Jun 5 - Jun 6
Total with taxes and fees
8.6/10 Excellent! (1,330 reviews)
"Very clean, friendly environment"
Reviewed on May 29, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Mission District
Mission Dolores Park
5/5(1 review)
Great views of downtown San Francisco, tree-shaded lawns and a children’s playground await at this popular hillside park in the vibrant Mission District.
Mission San Francisco de Asís
Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the notable monuments and shops in this vibrant area.
Balmy Alley
Balmy Alley is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed art scene in this vibrant area.
Things to do
Official Alcatraz Inside Prison Tour with Free App Audio Packages
$86
per adult
100% of travellers recommend
California Academy of Sciences Daytime Admission
$49
per adult
86% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
$125
per adult
94% of travellers recommend
Explore a world of travel with Expedia
- San Francisco Hotels
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- Hotels near Downtown San Francisco
- Hotels near Hua Zang Si
- Hotels near Southern Exposure
- Hotels near Clarion Alley
- Hotels near Women's Building
- Hotels near Victoria Theatre
- Hotels near Marsh Theater
- Hotels near 16th Street Mission Station
- Motels in 16th Street Mission Station
- Hotels near San Francisco Public Library
- Hotels near 24th Street Mission Station
- Hotels near Ratio 3
- Hotels near Mission Dolores Park
- Hotels near Balmy Alley
- Hotels near SF Armory
- Hotels near Mission High School
- Hotels near Mission Dolores
- Hotels near Right Of Way/Liberty St Stop
- Hotels near Mission San Francisco de Asís
- Hotels near Hosfelt Gallery
- Hotels near Galería de la Raza
- Hotels near 22nd St Hill
- Hotels near Oracle Park
- Hotels near Union Square
- Vacation Homes in Church St & 24th St Stop
- Hotels near Market St & Dolores St Stop
- Hotels near Anchor Brewing Company
- Hotels near Castro District
- Hotels near Church Street Station
- Hotels near Market St & Buchanan St Stop
- Hotels near Market St & Guerrero St Stop
- Hotels near Market St & Laguna St Stop
- B&B in Church St & 14th St Stop
- Hotels near Market St & Sanchez St Stop
- Hotels near SOMArts
- Hotels near Church St & Clipper St Stop
- Hotels near U.S. Mint
- Hotels near Duboce Ave & Church St Stop
- Hotels near Emergence Healing Arts Studio
- Hotels near Bill Graham Civic Auditorium
- Gay friendly Hotels in Castro District
- Hotels near Castro Street
- San Francisco Vacations
- Hua Zang Si
- Marsh Theater
- Mission Dolores Park
- Sf Armory
- Mission San Francisco de Asís
- Galería de la Raza
- Castro Street
- 22nd St Hill
- Visit Downtown San Francisco
- Fouladi Projects
- San Francisco City Hall
- U.s. Mint
- Visit Mission Dolores
- Castro Theatre
- Harvey Milk Plaza
- San Francisco Zen Center
- Louise Davies Symphony Hall
- Noe Valley Vacations
- The Promenade
- Bill Graham Civic Auditorium
- Randall Museum
- Nobby Clarke Mansion
- Visit Castro District
- Randall Museum
- Golden Gate Model Railroad Club
- Mission Creek Park
- Corona Heights Park
- War Memorial Opera House
- Orpheum Theatre
- Civic Center Plaza
- Vulcan Steps
- Mclellan Botanicals
- Painted Ladies
- San Francisco Federal Building
- Kite Hill Open Space
- Asian Art Museum of San Francisco
- United Nations Plaza
- California State Building
- Alamo Square
- Haight Street
- Chase Center
- Van Ness Avenue
- Visit Bernal Heights
- Twin Peaks
- Academy of Art University
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.