Mission District Vacations from $523
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Your Mission District Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Mission District vacation package. However you picture yourself spending your days here, you'll find countless opportunities for fun, relaxation and adventure. Can't wait to get out and see the sights during your trip to Mission District? Be sure to check out nearby attractions like Lombard Street, University of San Francisco and University of California, San Francisco. Expedia is here to put your plans into action. Book your perfect Mission District vacation now.
The Latest Mission District Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The Westin St. Francis San Francisco on Union Square
Union Square
Save 100% on your flight
Price was $1,054, price is now $523 per person
$523
per person
May 14 - May 17
found 1 day ago
Roundtrip flight included
Dallas (DAL) to San Francisco (SFO)
8.8/10 Excellent! (2,383 reviews)
It's delusional, giving the price tag. Even the WiFi isn't really free. Room service feel like a trap with 9%+15% fee on restaurant dishes that don't show prices upfront!! Breakfast meaningless, check-in staff is really bad and confused, not forthcoming and definitely unhelpful.
Reviewed on Apr 7, 2026
Club Wyndham Canterbury
Union Square
Price was $2,477, price is now $644 per person
$644
per person
Jul 3 - Jul 6
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9.2/10 Wonderful! (733 reviews)
Great location, good-sized rooms, pretty clean, comfortable bed. The bathroom was pretty big, but there are no counters; the sink is very small, and there's no space for my makeup or facial products.
The area has many restaurant choices, within walking distance of shopping centers.
Reviewed on Apr 2, 2026
The Grove Inn
Western Addition
Save 100% on your flight
Price was $1,698, price is now $978 per person
$978
per person
Jun 21 - Jun 26
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9.2/10 Wonderful! (701 reviews)
It felt like a boarding house. No common area to sit on a couch and relax. Our window opened onto an air shaft and no view. Neighborhood parking is nonexistent so only stay if using Uber. The bed and bath were clean. However I would not stay there again.
Reviewed on Mar 29, 2026
Fairmont Heritage Place, Ghirardelli Square
Fisherman's Wharf
Save 100% on your flight
Price was $6,159, price is now $3,553 per person
$3,553
per person
Jul 2 - Jul 7
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9.4/10 Exceptional! (393 reviews)
Nothing but great things to say about this place! So much to do and see and staff is sooo nice and helpful.
Reviewed on Apr 5, 2026
1 Hotel San Francisco
Downtown San Francisco
Save 100% on your flight
Price was $2,124, price is now $1,228 per person
$1,228
per person
Jul 2 - Jul 7
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9.2/10 Wonderful! (525 reviews)
Amazing ambiance. Great staff and Daily Breakfast.
Reviewed on Apr 10, 2026
Where to stay in Mission District
Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Fisherman's Wharf
1 out of top 10 points of interest in this area
4/5(39 area reviews)
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
Mission District Hotel Deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $155 total per night from Apr 12 to Apr 13
$155 total
Apr 12 - Apr 13
Total with taxes and fees
9/10 Wonderful! (5,538 reviews)
Hotel was great. Room service everyday and front desk extremely helpful.
Reviewed on Apr 11, 2026
Handlery Union Square Hotel
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $155 total per night from Apr 22 to Apr 23
$155 total
Apr 22 - Apr 23
Total with taxes and fees
8.8/10 Excellent! (2,993 reviews)
Pool side not used. Parking expensive but secure
Reviewed on Apr 10, 2026
Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $196 total per night from Apr 12 to Apr 13
$196 total
Apr 12 - Apr 13
Total with taxes and fees
9/10 Wonderful! (7,386 reviews)
It was an amazing stay.. the staff, the food, the amenities and the lady that clean my room daily, it was all top quality! Thank you everyone.
Reviewed on Apr 11, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Mission District
Mission Dolores Park
5/5(1 review)
Great views of downtown San Francisco, tree-shaded lawns and a children’s playground await at this popular hillside park in the vibrant Mission District.
Mission San Francisco de Asís
Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the notable monuments and shops in this vibrant area.
Balmy Alley
Balmy Alley is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene and fascinating museums in this vibrant area.
Things to do
Official Alcatraz Island Prison Tour with Free App Audio Packages
$86
per adult
100% of travellers recommend
California Academy of Sciences Daytime Admission
$49
per adult
86% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
$139
per adult
94% of travellers recommend
Explore a world of travel with Expedia
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- San Francisco Vacations
- Hua Zang Si
- Marsh Theater
- Mission Dolores Park
- Sf Armory
- Mission San Francisco de Asís
- Galería de la Raza
- Castro Street
- 22nd St Hill
- Visit Downtown San Francisco
- Fouladi Projects
- San Francisco City Hall
- U.s. Mint
- Visit Mission Dolores
- Castro Theatre
- Harvey Milk Plaza
- San Francisco Zen Center
- Louise Davies Symphony Hall
- Noe Valley Vacations
- The Promenade
- Bill Graham Civic Auditorium
- Randall Museum
- Nobby Clarke Mansion
- Visit Castro District
- Randall Museum
- Golden Gate Model Railroad Club
- Mission Creek Park
- Corona Heights Park
- War Memorial Opera House
- Orpheum Theatre
- Civic Center Plaza
- Vulcan Steps
- Mclellan Botanicals
- Painted Ladies
- San Francisco Federal Building
- Kite Hill Open Space
- Asian Art Museum of San Francisco
- United Nations Plaza
- California State Building
- Alamo Square
- Haight Street
- Chase Center
- Van Ness Avenue
- Visit Bernal Heights
- Twin Peaks
- Academy of Art University
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.