Mission District Vacations from $312
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Your Mission District Vacation
Experience all the wonderful things this neighborhood has to offer with a tailor-made Mission District vacation package. However you picture yourself spending your days here, you'll find countless opportunities for fun, relaxation and adventure. Can't wait to get out and see the sights during your trip to Mission District? Be sure to check out nearby attractions like Lombard Street, University of San Francisco and University of California, San Francisco. Expedia is here to put your plans into action. Book your perfect Mission District vacation now.
The Latest Mission District Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Bay Landing San Francisco Airport Hotel
Ingold - Milldale
Save 100% on your flight
Price was $449, price is now $312 per person
$312
per person
May 5 - May 8
found 8 hours ago
Roundtrip flight included
Carlsbad (CLD) to San Francisco (SFO)
9/10 Wonderful! (4,822 reviews)
nice staff; functional most things
no water bottles - drink from the only tap in the room, next to the commode
TV cant olay youtube
Reviewed on Mar 15, 2026
Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Save 100% on your flight
Price was $1,022, price is now $660 per person
$660
per person
May 15 - May 19
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9/10 Wonderful! (7,413 reviews)
Great location-walking distance to the warf, North Beach and Chinatown. The breakfast buffet was outstanding! Like at an all inclusive resort. A wonderful property and friendly service.
Reviewed on Mar 15, 2026
Embassy Hotel
Downtown San Francisco
Price was $637, price is now $427 per person
$427
per person
May 5 - May 10
found 9 hours ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
6.6/10 (638 reviews)
Room was clean, good space, the only downside was room was a bit hot. It was near a good amount of food places and at walking distance.
Reviewed on Mar 13, 2026
The Westin St. Francis San Francisco on Union Square
Union Square
Save 100% on your flight
Price was $880, price is now $591 per person
$591
per person
Apr 16 - Apr 19
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
8.8/10 Excellent! (2,401 reviews)
Clean room, very helpful staff. Nice old hotel with old Wood features and high ceilings. Comfortable bed.
Reviewed on Mar 2, 2026
Beacon Grand, A Union Square Hotel
Union Square
Save 100% on your flight
Price was $1,294, price is now $871 per person
$871
per person
May 15 - May 19
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9.2/10 Wonderful! (1,926 reviews)
Nice but feels old in a bad way. Obviously it's a historic hotel but even the newer updates are worn out. The door seals are nonexistent, we heard every conversation of passerbys.
Reviewed on Mar 14, 2026
Where to stay in Mission District
Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Union Square
4/5(5,164 area reviews)
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Mission District Hotel Deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundable
$132 nightly
The price is $155 total per night from Apr 12 to Apr 13
$155 total
Apr 12 - Apr 13
Total with taxes and fees
9/10 Wonderful! (5,407 reviews)
Clean room, easy check-in, they let you stay parked up to the limit even after you check out.
Reviewed on Mar 15, 2026
Handlery Union Square Hotel
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $160 total per night from Mar 21 to Mar 22
$160 total
Mar 21 - Mar 22
Total with taxes and fees
8.8/10 Excellent! (2,915 reviews)
Hotel was clean, safe, well-staffed. Rooms were comfortable.
Reviewed on Mar 15, 2026
Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $208 total per night from Apr 12 to Apr 13
$208 total
Apr 12 - Apr 13
Total with taxes and fees
9/10 Wonderful! (7,353 reviews)
Breakfast was excellent, but there were so many rules that were unfortunate - making everyone from the room to be present to eat together, not allowing coffee to go, assigning places to sit, etc.
Reviewed on Mar 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Mission District
Mission Dolores Park
Great views of downtown San Francisco, tree-shaded lawns and a children’s playground await at this popular hillside park in the vibrant Mission District.
Mission San Francisco de Asís
Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the notable monuments and shops in this vibrant area.
Balmy Alley
Balmy Alley is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed theater scene in this vibrant area.
Things to do
Official Alcatraz Island Prison Tour with Free App Audio Packages
$86
per adult
100% of travellers recommend
California Academy of Sciences Daytime Admission
$49
per adult
86% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
$139
per adult
94% of travellers recommend
Explore a world of travel with Expedia
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- San Francisco Vacations
- Hua Zang Si
- Marsh Theater
- Mission Dolores Park
- Sf Armory
- Mission San Francisco de Asís
- Galería de la Raza
- Castro Street
- 22nd St Hill
- Visit Downtown San Francisco
- Fouladi Projects
- San Francisco City Hall
- U.s. Mint
- Visit Mission Dolores
- Castro Theatre
- Harvey Milk Plaza
- San Francisco Zen Center
- Louise Davies Symphony Hall
- Noe Valley Vacations
- The Promenade
- Bill Graham Civic Auditorium
- Randall Museum
- Nobby Clarke Mansion
- Visit Castro District
- Randall Museum
- Golden Gate Model Railroad Club
- Mission Creek Park
- Corona Heights Park
- War Memorial Opera House
- Orpheum Theatre
- Civic Center Plaza
- Vulcan Steps
- Mclellan Botanicals
- Painted Ladies
- San Francisco Federal Building
- Kite Hill Open Space
- Asian Art Museum of San Francisco
- United Nations Plaza
- California State Building
- Alamo Square
- Haight Street
- Chase Center
- Van Ness Avenue
- Visit Bernal Heights
- Twin Peaks
- Academy of Art University
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.