Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Mission Valley Family Hotels

See all 1,062 Hotels in Mission Valley
Comfort Inn & Suites San Diego - Zoo SeaWorld Area

Comfort Inn & Suites San Diego - Zoo SeaWorld Area

2485 Hotel Circle Place, San Diego
2.5 out of 5.0
3.8 out of 5 (1,101 reviews)
Breakfast buffet was disorganized . But hotel was nice.
  Oct 18, 2017

$85

$85
Kings Inn San Diego - Seaworld - Zoo

Kings Inn San Diego - Seaworld - Zoo

1333 Hotel Cir S, San Diego
2.5 out of 5.0
3.9 out of 5 (1,559 reviews)
Great place to stay.Stay here every time we visit San Diego. The hotel staff are so welcoming from the cleaners up to management at the front desk. The rooms are spotless, good breakfast at the waffle spot, good food in the restaurant and a friendly bar.. The pool area is great to catch some rays, plenty of loungers ...
  Oct 16, 2017

$84

$84
Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley

1865 Hotel Cir S, San Diego
3.0 out of 5.0
4.3 out of 5 (291 reviews)
Nice but front desk help makes negative comments Received negative comments by front desk staff because I booked from a travel site, didn't seem like they were interested in helping with a mistake in the reservation because of it.
  Oct 12, 2017

$164

$164
Days Inn San Diego Hotel Circle Near SeaWorld

Days Inn San Diego Hotel Circle Near SeaWorld

543 Hotel Circle S, San Diego
3.0 out of 5.0
3.7 out of 5 (2,666 reviews)
It was nice to stay daysinn, it's near downtown and beaches.
  Oct 18, 2017

$85

$85
La Quinta Inn & Suites San Diego SeaWorld/Zoo Area

La Quinta Inn & Suites San Diego SeaWorld/Zoo Area

641 Camino Del Rio S, San Diego
2.5 out of 5.0
3.7 out of 5 (990 reviews)
Perfect loactionLa Quinta Inn was a perfect location for the concert that we attended at the stadium which was only 15 minutes away. The trolley is 5 min away with a lot of stores and restaurants. Would definitely stat here again.
  Oct 11, 2017

$89

$89
Best Western Seven Seas

Best Western Seven Seas

411 Hotel Circle South, San Diego
3.0 out of 5.0
3.6 out of 5 (2,561 reviews)
would recommend Spent two night here at the end of our trip. Easy acccess to the harbour and gaslight via tram can walk to station easily as you. Get free parking at the hotel much easier to walk. Good pool area nice gardens.
  Oct 16, 2017

$68

$68
Quality Suites San Diego SeaWorld Area

Quality Suites San Diego SeaWorld Area

631 Camino Del Rio S, San Diego
2.5 out of 5.0
3.6 out of 5 (533 reviews)
Fun in the SunNice place, great value, great location. The staff was very pleasant.
  Oct 17, 2017

$76

$76
DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle

1515 Hotel Cir S, San Diego
4.0 out of 5.0
3.9 out of 5 (965 reviews)
Booked this room for one night just to sleep! It's close to the airport. It was safe, clean and inviting. If I had more time to use the pool we would have! It looked refreshing!
  Oct 9, 2017

$109

$109
Town and Country San Diego

Town and Country San Diego

500 Hotel Cir N, San Diego
3.5 out of 5.0
3.1 out of 5 (497 reviews)
Our Anniversary PlaceOur stay here was great.. friendly staff, great environment, quite, clean, very modern and spacious... we really loved our room.. simple yet still the best compared to those expensive and known hotels.. looking forward on staying here again 😊
  Oct 10, 2017

$90

$90
San Diego Marriott Mission Valley

San Diego Marriott Mission Valley

8757 Rio San Diego Dr, San Diego
4.0 out of 5.0
4.1 out of 5 (348 reviews)
Nice Hotel Close to Qualcomm StadiumNice hotel close to Qualcomm Stadium and Trolley Station
  Oct 14, 2017

$139

$139
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

1433 Camino Del Rio S, San Diego
4.0 out of 5.0
4.0 out of 5 (690 reviews)
Great location, clean room, great serviceI was extremely please with Sheraton Mission Valley San Diego Hotel. It`s in a great location. A quick drive to anywhere you may want to go in San Diego. The staff was absolutely lovely. The bed was big and comfortable and the room was super clean. It`s not a fancy hotel, but it`s a very comfortable ...
  Oct 3, 2017

$110

$110
Hampton Inn San Diego Mission Valley

Hampton Inn San Diego Mission Valley

2151 Hotel Circle South, San Diego
2.5 out of 5.0
4.5 out of 5 (279 reviews)
Great hotel close to everything!Beautiful lobby and pool area, great hospitality, best complimentary breakfast I've had!
  Oct 16, 2017

$101

$101
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

7450 Hazard Center Dr, San Diego
4.0 out of 5.0
4.2 out of 5 (669 reviews)
In a summary, this hotel is not among the best but is above average. Will recommend to friends for a short stay.
  Oct 16, 2017

$120

$120
Holiday Inn Express & Suites San Diego - Mission Valley

Holiday Inn Express & Suites San Diego - Mission Valley

635 Hotel Circle South, San Diego
3.0 out of 5.0
4.5 out of 5 (169 reviews)
Hotel StyleVery nicely designed hotel colorful, bright and clean.
  Oct 18, 2017

$112

$112
Mission Valley Resort

Mission Valley Resort

875 Hotel Cir South, San Diego
2.5 out of 5.0
2.2 out of 5 (2,211 reviews)
Hotel is close to a lot of attractions.The hotel is in a tourist zone (hotel zone). The hotel is under construction, the grass looked as if it hadn't been mowed in a couple of weeks. The people riding their bikes around the around were scary looking. Their beds are very comfortable, their carpet is old, their TVs only offered one channel ...
  Aug 2, 2017
Handlery Hotel

Handlery Hotel

950 Hotel Cir N, San Diego
3.5 out of 5.0
3.6 out of 5 (809 reviews)
Nice hotel with a good pool area.The hotel is quite nice and quiet. The restaurant is good, and the pool area is very nice. The rooms are clean and comfortable. The only issue we had was with the WiFi. It was very spotty, and some days didn't work at all.
  Oct 17, 2017

$99

$99
Courtyard by Marriott San Diego Mission Valley/Hotel Circle

Courtyard by Marriott San Diego Mission Valley/Hotel Circle

595 Hotel Circle South, San Diego
3.0 out of 5.0
4.1 out of 5 (372 reviews)
Nice HotelWe had a quick 24 hour stay. Hotel was clean and comfortable. The staff is wonderful in assisting with whatever you may need.
  Oct 16, 2017

$129

$129
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

901 Camino Del Rio S, San Diego
4.0 out of 5.0
3.8 out of 5 (914 reviews)
Great experience! Very clean and nice. I recommend it.
  Oct 15, 2017

$129

$129
Motel 6 San Diego - Hotel Circle - Mission Valley

Motel 6 San Diego - Hotel Circle - Mission Valley

2424 Hotel Circle North, San Diego
2.0 out of 5.0
3.1 out of 5 (333 reviews)
No comforters very tiny rooms and ok cleaning, not excellent. But staff were friendly and answered my queries quickly. No shop for brush and tooth paste, they should have one vendor or vending machine for this.
  Sep 19, 2017

$60

$60
Homewood Suites by Hilton San Diego Hotel Circle/Sea World

Homewood Suites by Hilton San Diego Hotel Circle/Sea World

2201 Hotel Circle S, San Diego
3.0 out of 5.0
4.5 out of 5 (52 reviews)
Terrific!A great motel. Extremely nice facility with beautiful rooms and very nice pool & hot tub. Breakfast and evening happy hour were quite Enjoyable.
  Oct 18, 2017

$147

$147
Map

Recently booked Family Hotels in Mission Valley

Days Inn Mission Valley - Qualcomm - SDSU
2.0 out of 5.0
Last booking: 11 minutes ago
Days Inn San Diego Hotel Circle Near SeaWorld
3.0 out of 5.0
Last booking: 44 minutes ago
Holiday Inn Express & Suites San Diego - Mission Valley
3.0 out of 5.0
Last booking: 45 minutes ago
Handlery Hotel
3.5 out of 5.0
Last booking: 52 minutes ago
Best Western Seven Seas
3.0 out of 5.0
Last booking: 1 hour ago
Town and Country Resort & Convention Center
3.5 out of 5.0
Last booking: 1 hour ago
Crowne Plaza Hanalei San Diego - Mission Valley
3.5 out of 5.0
Last booking: 1 hour ago
DoubleTree by Hilton San Diego - Hotel Circle
4.0 out of 5.0
Last booking: 1 hour ago
Motel 6 San Diego Mission Valley East
2.0 out of 5.0
Last booking: 2 hours ago

Ready for a vacation your family will remember forever? Find out why a great deal of travelers like you have booked a trip to Mission Valley this year. Travelers are increasingly showing interest in this city due to all the interesting attractions and activities you'll find in town. Whether you're making friends with other vacationing families or getting travel advice from the locals, you'll leave town happy.

Find the Supreme Mission Valley Family Hotel

Looking for a place that will meet all your family's needs? At Expedia.com, we offer countless hotel options, so you have a number to sort through until you find the ideal one for your family. Find a place within easy access of all the family-friendly attractions or choose one that is spacious enough for your whole gang. Whether your family wants to embark on adventures or simply relax in your hotel room, the ideal accommodation is waiting for you to book today.

As Mission Valley continues to climb in popularity, everyone is flocking here for a family vacation. In fact, this destination saw lots of vacationers last year, and you can read all the useful tips they left in our review section. You'd be surprised at just how many people would suggest that others stay at the same place as them! As soon as you show up, you'll understand why these places earned such high marks. The rooms are clean and tidy, while the property grounds are especially alluring. Furthermore, you'll know you're in good hands thanks to the helpful hotel staff.

It's always a good time in Mission Valley, and your family will be sad to return home. The time is now to show your family how much you love them, and just you wait, it just might become something that your whole family looks forward to in the future. Pinpoint your Mission Valley family hotel today, and you'll wonder why you didn't do it sooner!