Find hotels in New Melle, MO from $68

The best area to stay in New Melle is in the heart of the town itself, particularly around the intersection of Highway D and Foristell Road. This central location offers convenient access to the town's main establishments.Couples looking for a peaceful getaway will appreciate this area. New Melle is known for its rural setting and quiet atmosphere, providing a relaxing escape from city life. You'll find local eateries and shops within a short drive, making it easy to enjoy the town's offerings without extensive travel.For those interested in exploring the scenic countryside and local attractions, staying centrally in New Melle is ideal.

The best time to visit New Melle is during the spring (April to June) and fall (September to October) months.These seasons offer the most pleasant weather conditions, with comfortable temperatures and less humidity, making it ideal for exploring the outdoors and enjoying local events. Spring brings blooming wildflowers and lush greenery, while fall showcases beautiful foliage, creating a scenic backdrop for your visit.For visitors interested in outdoor activities like hiking, cycling, or exploring the local wineries, these shoulder seasons provide the great climate. The mild temperatures allow for extended periods outdoors without the discomfort of summer heat or winter cold, making it a great time for couples or solo travelers to enjoy the natural beauty of the area.

With Expedia, you earn OneKeyCash™* on eligible New Melle hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.