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Featured Orangeburg Independent Hotels

See all 60 Hotels in Orangeburg
Country Inn & Suites By Carlson, Orangeburg, SC

Country Inn & Suites By Carlson, Orangeburg, SC

731 Citadel Road, Orangeburg
3.0 out of 5.0
3.8 out of 5 (276 reviews)
Reliably good hotel. Clean and cozy. Competent staff. Comfortable stay We always enjoy our stay her … - 

$93

$93
Red Roof Inn Santee

Red Roof Inn Santee

9091 Old Hwy 6, Santee
2.5 out of 5.0
2.8 out of 5 (162 reviews)
Last mi ute Although lobby needs help the room was a nice siz and clean, beds comfortable and staff helpful. Re … - 

$52

$52
Travelodge Orangeburg

Travelodge Orangeburg

3620 Saint Matthews Rd, Orangeburg
2.5 out of 5.0
3.9 out of 5 (20 reviews)
Very friendly staff Should have higher ratings. We enjoyed our stay. The staff was friendly. The food was good. - 

$54

$54
SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

2816 Paxville Highway, Manning
3.0 out of 5.0
3.7 out of 5 (250 reviews)
Very convenient if you have pets. Right off of interstate 95. - 

$63

$63
Days Inn St George

Days Inn St George

139 Motel Dr, St. George
3.0 out of 5.0
3.5 out of 5 (310 reviews)
Nice location, great breakfast. We enjoyed this hotel. It was clean and reasonable. The continental breakfast was very nice and the … - 

$57

$57
Southern Lodge

Southern Lodge

3616 Saint Matthews Rd, Orangeburg
2.5 out of 5.0
3.4 out of 5 (112 reviews)
Room was nice and clean. The staff was nice and accommodated my need to check in a little early. - 

$51

$51
Peach Tree Inn

Peach Tree Inn

111 Conners Dr, St. George
3.0 out of 5.0
3.5 out of 5 (738 reviews)
You get what you pay for. A little shabby and run down. Not exactly sin and span, but OK. No WiFi because it was raining. WiF … - 

$58

$58
Holiday Inn Express Hotel & Suites Orangeburg

Holiday Inn Express Hotel & Suites Orangeburg

118 Sleep Inn Dr, Orangeburg
3.0 out of 5.0
4.1 out of 5 (184 reviews)
Very friendly staff. And the bed was extra comfortable. - 

$112

$112
Holiday Inn Santee

Holiday Inn Santee

139 Bradford Blvd, Santee
3.5 out of 5.0
3.9 out of 5 (207 reviews)
Nice hotel but breakfast not included Nice building, clean and comfortable room, good parking, typical hotel area restaurants nearby and … - 

$134

$134
Sleep Inn Orangeburg

Sleep Inn Orangeburg

3689 Saint Matthews Rd, Orangeburg
3.0 out of 5.0
3.7 out of 5 (100 reviews)
short stay but perfect for a traveler wanting a good nights sleep and to get back on the road again … - 

$67

$67
Whitten Inn

Whitten Inn

123 Mall Street, Santee
2.0 out of 5.0
2.5 out of 5 (102 reviews)
Ok for the price This hotel is old and worn! I've stayed here several times and there's always something in the room … - 

$69

$69
Winton Inn & Suites

Winton Inn & Suites

8273 Marlboro Avenue, Barnwell
3.0 out of 5.0
2.5 out of 5 (20 reviews)
Windows need room darkening shade. Bed very comfortable. Convenient location - 

$59

$59
Southern Lodge & Suites

Southern Lodge & Suites

1017 Chestnut St NE, Orangeburg
2.0 out of 5.0
2.3 out of 5 (23 reviews)
Could've been better. Room stay would've been better if not for loud people in next room. The toilet was making funny noi … - 

$50

$50
Carolina Lodge

Carolina Lodge

10645 Dunbarton Blvd., Barnwell
2.5 out of 5.0
3.2 out of 5 (36 reviews)
Excellent choice and convenience From the time of chicken to the time of departure. We enjoyed our stay at this hotel and we've alre … - 

$65

$65
Rodeway Inn and Suites

Rodeway Inn and Suites

1415 John C Calhoun Drive, Orangeburg
3.0 out of 5.0
1.2 out of 5 (8 reviews)

$70

$70
Elite Inn

Elite Inn

115 Winningham Rd, St. George
2.5 out of 5.0
2.0 out of 5 (3 reviews)
Room was decent and clean. Hotel was what we expected. Clean bed and bath. A place to get a nights skeep while we were traveli … - 

$49

$49
Lake Front Paradise! Water Front Dock Great for Fishing & Swimming!

Lake Front Paradise! Water Front Dock Great for Fishing & Swimming!

112 Fountain Lake Drive, Eutawville
4.9 out of 5 (9 reviews)
Econo Lodge Inn and Suites

Econo Lodge Inn and Suites

1415 John C Calhoun Drive, Orangeburg
2.5 out of 5.0
2.2 out of 5 (19 reviews)
Faded glory The staff bent over backwards to get us a room. Expedia and Hotels.com had both way overbooked desp … - 

$40

$40
Ashley Lodge

Ashley Lodge

188 Judge Street, Harleyville
2.5 out of 5.0
1.6 out of 5 (19 reviews)

$60

$60
Designer Lake House - Newly Renovated

Designer Lake House - Newly Renovated

134 State Road S-38-1543, Vance
3.9 out of 5 (10 reviews)
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Recently booked Orangeburg hotels

Holiday Inn Santee
3.5 out of 5.0
Last booking: 6 hours ago
Baymont Inn & Suites Orangeburg North
3.0 out of 5.0
Last booking: 7 hours ago
Country Inn & Suites By Carlson, Orangeburg, SC
3.0 out of 5.0
Last booking: 9 hours ago
Hampton Inn & Suites Orangeburg
3.0 out of 5.0
Last booking: 11 hours ago
Holiday Inn Express Hotel & Suites Orangeburg
3.0 out of 5.0
Last booking: 17 hours ago
Orangeburg - Days Inn South
2.5 out of 5.0
Last booking: 34 hours ago
Knights Inn Santee
2.5 out of 5.0
Last booking: 34 hours ago
Comfort Inn & Suites
3.0 out of 5.0
Last booking: 40 hours ago
Best Western Plus Santee Inn
2.5 out of 5.0
Last booking: 43 hours ago

Independent Orangeburg Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Orangeburg, South Carolina. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Orangeburg hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Orangeburg Independent locations may even offer extra little benefits and discounts for frequent travelers.