Ostiense Vacations from $670

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Relais de la Poste

Relais de la Poste

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,187, price is now $670 per person
$670
per person
Dec 8 - Dec 12
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.2/10 Wonderful! (574 reviews)
Best location. Clean. Mattress was a little bit hard. Would recommend

Reviewed on Oct 5, 2025

Monastero dei Santi

Monastero dei Santi

5 out of 5
Municipio I
Save 100% on your flight
Price was $1,373, price is now $815 per person
$815
per person
Dec 8 - Dec 13
found 15 hours ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
10/10 Exceptional! (23 reviews)
Elegant and renovated boutique hotel

Reviewed on Jul 5, 2025

The Fifteen Keys Hotel

The Fifteen Keys Hotel

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,591, price is now $1,048 per person
$1,048
per person
Dec 8 - Dec 13
found 15 hours ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.8/10 Exceptional! (367 reviews)
Amazing- would stay again

Reviewed on Sep 29, 2025

Grand Hotel Olympic

Grand Hotel Olympic

4 out of 5
Rome City Centre
Price was $1,200, price is now $756 per person
$756
per person
Nov 8 - Nov 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
7.4/10 Good! (1,020 reviews)
Position was great for shopping and eating

Reviewed on Oct 4, 2025

Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
Price was $1,575, price is now $1,033 per person
$1,033
per person
Nov 25 - Nov 30
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.4/10 Exceptional! (240 reviews)
It was a leisurely ten minute walk from the underground and available shopping and food sources. I would gladly stay again for any length of time.

Reviewed on Oct 1, 2025

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Napoleon Hotel

Napoleon Hotel

4 out of 5
Piazza Vittorio Emanuele II 105, Rome, RM
$171 nightly
The price is $205 total per night from Nov 2 to Nov 3
$205 total
Nov 2 - Nov 3
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
"The hotel itself is quite nice. The rooms very comfortable. Everything was quite clean. The restaurant in the hotel was nice. The rooftop bar was fun. The hotel is conveniently located near enough to the train station to walk, but far enough to not be bothered by it. Naples, unfortunately is not ..."

Reviewed on Sep 29, 2025

Napoleon Hotel
Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7, Rome, RM
$228 nightly
The price is $269 total per night from Nov 2 to Nov 3
$269 total
Nov 2 - Nov 3
Total with taxes and fees
8.6/10 Excellent! (1,882 reviews)
"A beautiful hotel with 5 star service. Centrally located"

Reviewed on Oct 2, 2025

Hotel Quirinale
The Social Hub Rome

The Social Hub Rome

Viale Scalo San Lorenzo 10, Rome, RM
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $165 total per night from Nov 2 to Nov 3
$165 total
Nov 2 - Nov 3
Total with taxes and fees
9/10 Wonderful! (419 reviews)
"Before travelling to Italy I’d never heard of or stayed in any Social Hub Hotels, but I have to say that I’m now a fan! The location in Rome is a bit out of the way, and is a 15-20 minute walk from the main railway station, though you can also get a short tram ride down to the hotel as well. In spite ..."

Reviewed on Oct 2, 2025

The Social Hub Rome
See all 15,765 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Ostiense

Basilica of St. Paul Outside the Walls

Basilica of St. Paul Outside the Walls

You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area.

Basilica of St. Paul Outside the Walls
#GoodEats “Bucatini all’Amatriciana” 😋🤤 Taste of home ❤️

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Eataly Roma

Roma Tre University

Walk around the campus at Roma Tre University during your stay in Rome. Visit the churches and notable monuments in this vibrant area.

Roma Tre University

Things to do

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$40
per adult
88% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$34
per adult
82% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$35
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.