Ostiense Vacations from $938

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Smart Guesthouse

Smart Guesthouse

3 out of 5
Rome City Centre
Save 100% on your flight
per person
Oct 26 - Nov 1
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.4/10 Exceptional! (56 reviews)
Clean and comfortable. Check in 3PM, check out 10AM. Free wifi, bottle water, espresso machine. Good linens and nice bed.

Reviewed on Aug 16, 2025

Grand Hotel Olympic

Grand Hotel Olympic

4 out of 5
Rome City Centre
Save 100% on your flight
per person
Oct 8 - Oct 15
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
7.2/10 Good! (1,011 reviews)
Nice and clean but noise from outside. Good breakfast.

Reviewed on Aug 18, 2025

Vibe Nazionale

Vibe Nazionale

3 out of 5
Rome City Centre
Save 100% on your flight
per person
Oct 19 - Oct 25
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
8/10 Very Good! (61 reviews)
Great location, rooms in good condition, good breakfast with outstanding staff working the breakfast room. But the front desk was rude and generally unhelpful. (Exception was Margarita, who was outstanding). Would not stay there again. V

Reviewed on Oct 3, 2023

CC Palace Hotel Roma

CC Palace Hotel Roma

4 out of 5
Rome City Centre
Save 100% on your flight
per person
Oct 26 - Nov 1
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.8/10 Exceptional! (345 reviews)
Clean property with excellent breakfast and service. Value for money was likely not there.

Reviewed on Aug 3, 2025

Piazza di Spagna Suite de Charme

Piazza di Spagna Suite de Charme

1 out of 5
Rome City Centre
Save 100% on your flight
per person
Oct 19 - Oct 24
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.2/10 Wonderful! (217 reviews)
Good location and customer service. Small room but for 2 nights it was very good!

Reviewed on Jul 6, 2025

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7, Rome, RM
Fully refundableReserve now, pay when you stay
$206 nightly
The price is $245 total per night from Aug 24 to Aug 25
$245 total
Aug 24 - Aug 25
Total includes taxes and fees
8.4/10 Very Good! (1,857 reviews)
A great stay
"Everything about this hotel was amazing. The room was great. The food was delicious. The receptionist were helpful. I would love to stay here again and soon."

Reviewed on Aug 18, 2025

Hotel Quirinale
The Social Hub Rome

The Social Hub Rome

Viale Scalo San Lorenzo 10, Rome, RM
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $164 total per night from Aug 24 to Aug 25
$164 total
Aug 24 - Aug 25
Total includes taxes and fees
9/10 Wonderful! (289 reviews)
"Very good hotel with free laundry room, a section with pool and ping pong tables. Restaurant was actually good. Also there is a walking section with lounge tables that was nice Felt safe in the hotel. Only drawback is the area around the hotel is not nice so we usually took taxis. However I recommend ..."

Reviewed on Aug 10, 2025

The Social Hub Rome
The Hive Hotel

The Hive Hotel

4 out of 5
Via Torino 6, Rome, RM
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $161 total per night from Aug 24 to Aug 25
$161 total
Aug 24 - Aug 25
Total includes taxes and fees
9/10 Wonderful! (1,551 reviews)
"Love it!"

Reviewed on Aug 12, 2025

The Hive Hotel
See all 15,661 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Ostiense

Basilica of St. Paul Outside the Walls

Basilica of St. Paul Outside the Walls

You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area.

Basilica of St. Paul Outside the Walls
#GoodEats “Bucatini all’Amatriciana” 😋🤤 Taste of home ❤️

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed theater scene in this vibrant area.

Eataly Roma

Roma Tre University

Walk around the campus at Roma Tre University during your stay in Rome. Visit the stunning cathedral and notable monuments in this vibrant area.

Roma Tre University

Things to do

Underground Rome Catacombs Tour with Aqueducts & Appian Way

Underground Rome Catacombs Tour with Aqueducts & Appian Way

$58
per adult
94% of travellers recommend
Underground Rome Catacombs Tour with Aqueducts & Appian Way
Ancient Ostia Antica Semi-Private Day Trip from Rome by Train with Guide

Ancient Ostia Antica Semi-Private Day Trip from Rome by Train with Guide

$69
per adult
98% of travellers recommend
Ancient Ostia Antica Semi-Private Day Trip from Rome by Train with Guide
3-Day Southern Italy Tour: Naples, Pompeii, Sorrento & Capri from Rome

3-Day Sorrento, Capri & Pompeii Mini Tour

$1,184
per traveler
80% of travellers recommend
3-Day Sorrento, Capri & Pompeii Mini Tour
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.