Ostiense Vacations from $1,203

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Grand Hotel Olympic

Grand Hotel Olympic

Rome City Centre
Save 100% on your flight
$1,203
per person
Oct 10 - Oct 15
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
7.8/10 Good! (1,118 reviews)
The property is dated and could use some renovation especially the bathrooms. The cleaning lady was very sweet and cleaned as much as she could but the rooms and bathrooms itself do need some TLC.

Reviewed on Aug 18, 2026

Hotiday Roma Trevi

Hotiday Roma Trevi

Rome City Centre
Save 100% on your flight
$1,788
per person
Oct 23 - Oct 26
found 1 day ago
Roundtrip flight included
Miami (MIA) to Rome (FCO)
No reviews
Monastero dei Santi

Monastero dei Santi

Municipio I
Save 100% on your flight
$2,005
per person
Oct 10 - Oct 15
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.8/10 Exceptional! (31 reviews)
Great staff, beautiful views, huge rooms and terraces!

Reviewed on Jul 2, 2026

Parco dei Principi Grand Hotel & SPA - Preferred Hotels & Resorts

Parco dei Principi Grand Hotel & SPA - Preferred Hotels & Resorts

Pinciano
Save 100% on your flight
$3,134
per person
Oct 10 - Oct 15
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9/10 Wonderful! (885 reviews)
ROMEO Roma

ROMEO Roma

Rome City Centre
Save 100% on your flight
$4,161
per person
Oct 10 - Oct 15
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
10/10 Exceptional! (1 review)
Glorious property, 3-Star food, 5-star service.

Reviewed on May 23, 2026

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre
A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

Find hotels in Rome Historic Centre
The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

Find hotels in Monti
A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

Find hotels in Trastevere
A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

Find hotels in Trevi

Ostiense Hotel Deals

Cardo Roma, Autograph Hotel

Cardo Roma, Autograph Hotel

Viale Del Pattinaggio 100 Rome RM
Fully refundableReserve now, pay when you stay
$162 nightly
$196 total
Aug 23 - Aug 24
Total with taxes and fees
9.2/10 Wonderful! (128 reviews)
"Clean room, great amenities, 20 mins away from the city Centre."

Reviewed on Aug 17, 2026

Cardo Roma, Autograph Hotel
Aparthotel Colombo Roma

Aparthotel Colombo Roma

Via Cristoforo Colombo 112 Rome RM
Fully refundableReserve now, pay when you stay
$50 nightly
$72 total
Aug 25 - Aug 26
Total with taxes and fees
9.2/10 Wonderful! (459 reviews)
"Everything was fine."

Reviewed on Aug 18, 2026

Aparthotel Colombo Roma
Hotel Quirinale

Hotel Quirinale

Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$167 nightly
$201 total
Aug 23 - Aug 24
Total with taxes and fees
8.8/10 Excellent! (1,928 reviews)
"Such a cute hotel! The front desk staff were very friendly. The breakfast was very good with lots of options. The rooms were spacious (I believe they upgraded our original room reservation when we checked in), clean and nicely decorated. My only complaint is the layout of the hotel can be sort of ..."

Reviewed on Aug 18, 2026

Hotel Quirinale
See all 16,727 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Ostiense attractions

Basilica of St. Paul Outside the Walls

9.0/10 (762 reviews)
You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the stunning cathedral and notable monuments in this vibrant area.
See properties

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
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Art Center Acea

6.0/10 (1 review)
Enjoy an outing to Art Center Acea during your stay in Rome. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
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Luneur Park

8.0/10 (2 reviews)
Bring the kids to Luneur Park and have a fun-filled day at this amusement park in Rome. While in the area, you can find time to visit its cathedral.
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Tre Fontane Stadium

Catch an event at Tre Fontane Stadium during your trip to Rome. While in the area, you can find time to visit its cathedral.
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Montemartini Museum

8.0/10 (1 review)
You can study the exhibits at Montemartini Museum, a museum with a story of its own, during your travels to Rome. Visit the stunning cathedral and notable monuments in this vibrant area.
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ACEA Heritage

You can enjoy some culture when you stop by ACEA Heritage in Rome. While in the area, you can find time to visit its cathedral.
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Goa Club

Goa Club is just one of the places to see in Rome, so why not enjoy the other things to explore during your travels? While in the area, you can find time to visit its cathedral.
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Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$26
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$79
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Rome in a Day: Small Group Tour with Vatican, Colosseum & Historic Center

Rome in a Day: Small Group Tour with Vatican, Colosseum & Historic Center

$207
per adult
96% of travellers recommend
Rome in a Day: Small Group Tour with Vatican, Colosseum & Historic Center
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.