Beginning of main content

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Palmdale Business Hotels

See all 37 Hotels in Palmdale
Holiday Inn Palmdale-Lancaster

Holiday Inn Palmdale-Lancaster

38630 5th St W, Palmdale
3.5 out of 5.0
4.1 out of 5 (409 reviews)
Excellent staff, very clean, great breakfastThe staff went above and beyond to make sure I was comfortable in my stay, I gave them the five stars review in everything, because even when they were under remodeling/construction, it was a very pleasant stay. the place is very clean, close to restaurants, the bar/restaurant at the hotel is ...
  Jan 9, 2018

$85

$85
Staybridge Suites Palmdale

Staybridge Suites Palmdale

420 Westpark Drive, Palmdale
3.5 out of 5.0
4.5 out of 5 (93 reviews)
Didn't realize all rooms were suitesI often visit my parents in Palmdale and usually we stay at the Motel 6. We recently had a bad experience there and wanted something nicer. The Staybridge had the best rating for the price. We were very pleasantly surprised at how nice the room was. If we had known it was a suite we would have taken ...
  Sep 8, 2017

$126

$126
Best Western Plus John Jay Inn & Suites

Best Western Plus John Jay Inn & Suites

600 W Palmdale Blvd, Palmdale
3.0 out of 5.0
4.2 out of 5 (517 reviews)
It was very nice. I will be sure to come here again..I was very impressed with the property.
  Dec 13, 2017

$89

$89
Ramada Palmdale

Ramada Palmdale

300 W Palmdale Blvd, Palmdale
3.0 out of 5.0
3.3 out of 5 (571 reviews)
My stay was very brief but very relaxing and comfortable as it always is
  Dec 28, 2017

$62

$62
Hampton Inn Suites Palmdale

Hampton Inn Suites Palmdale

39428 Trade Center Dr, Palmdale
3.0 out of 5.0
4.4 out of 5 (384 reviews)
Good locationEverything at the hotel was great except we got on room on Xmas Eve where the heat couldn't be regulated. Traveling with my 97 yr old Mother who requires warmth it just didn't happen. Hotel did everything they could, even offering another room but moving after we had unpacked was just too much for ...
  Dec 27, 2017

$105

$105
Embassy Suites Palmdale

Embassy Suites Palmdale

39375 5th St W, Palmdale
4.0 out of 5.0
4.6 out of 5 (734 reviews)
THE BEST FOR THE MONEYThe staff at this Embassy are very helpful and pleasant. W always enjoy staying with you.
  Jan 5, 2018

$139

$139
Hilton Garden Inn Palmdale

Hilton Garden Inn Palmdale

1309 W Rancho Vista Blvd, Palmdale
3.5 out of 5.0
4.5 out of 5 (394 reviews)
Pleasing StayI enjoyed my stay, it was conveniently located near bar I was celebrating with my friends. Checking in was easy and fast, and the receptionist was really friendly and nice.
  Jan 7, 2018

$93

$93
Courtyard Palmdale

Courtyard Palmdale

530 West Rancho Vista Blvd., Palmdale
3.5 out of 5.0
4.3 out of 5 (145 reviews)
Clean hotel. This is why I always book at Marriott.
  Dec 25, 2017

$149

$149
E-Z 8 Motel Palmdale

E-Z 8 Motel Palmdale

430 W Palmdale Boulevard, Palmdale
3.0 out of 5.0
3.1 out of 5 (68 reviews)
Cheap hotel. Exactly what we wanted! Super close to the airport.
  Sep 12, 2017

$55

$55
Residence Inn by Marriott Palmdale

Residence Inn by Marriott Palmdale

514 W Avenue P, Palmdale
3.5 out of 5.0
4.3 out of 5 (60 reviews)
Convenient to freeway and lots of dining options nearby.
  Aug 21, 2017

$143

$143
Knights Inn Palmdale Lancaster Area

Knights Inn Palmdale Lancaster Area

130 E Palmdale Blvd, Palmdale
2.0 out of 5.0
3.1 out of 5 (816 reviews)
Very good experience just a bit noisy neighbors downstairs.
  Jan 9, 2018

$58

$58
Map

Recently booked Business Hotels in Palmdale

Holiday Inn Palmdale-Lancaster
3.5 out of 5.0
Last booking: 5 hours ago
Hilton Garden Inn Palmdale
3.5 out of 5.0
Last booking: 6 hours ago
Ramada Palmdale
3.0 out of 5.0
Last booking: 8 hours ago
Hampton Inn Suites Palmdale
3.0 out of 5.0
Last booking: 9 hours ago
Embassy Suites Palmdale
4.0 out of 5.0
Last booking: 19 hours ago
Best Western Plus John Jay Inn & Suites
3.0 out of 5.0
Last booking: 21 hours ago

Pocket Guide: Business Hotels in Palmdale

Search for hotels in Palmdale on Expedia. You can easily find your hotels in Palmdale using one of the methods below:

  • View our selection of featured hotels in Palmdale
  • Use the map to find hotels in the Palmdale neighborhood you prefer
  • Use the filters to see hotels in a specific area of Palmdale, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Palmdale
  • Enter your travel dates to view the best deals on hotels in Palmdale - while they last