Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Panama City

Best deal Best deal Jul 27 - Jul 29
Tonight Tonight Jun 18 - Jun 19
This weekend This weekend Jun 22 - Jun 24
Next weekend Next weekend Jun 29 - Jul 1

Featured Panama City Casinos

See all 164 Hotels in Panama City
Veneto Hotel & Casino

Veneto Hotel & Casino

Eusebio A Morales Ave And Via Veneto Str, Panama City
    2.5 out of 5.0
     
     
    3.3 out of 5 (1,412 reviews)
    Great nite lifeThe reason I like this hotel is the nitelife. It is a great location to hit the other Panama City spots. Carnival was a great time. And the staff is excellent and will help you get anywhere you need to go. Front desk helped me immensely multiple times. Security also there constantly to help and keep ...
    Feb 14, 2018

    Veneto Hotel & Casino$34

    Veneto Hotel & Casino$34
    Sortis Hotel, Spa & Casino, Autograph Collection

    Sortis Hotel, Spa & Casino, Autograph Collection

    56 y 57 East Street, Obarrio, Panama City
    • Free Cancellation
    • Reserve now, pay when you stay
    4.5 out of 5.0
     
     
    4.4 out of 5 (269 reviews)
    Nice hotels with great amenitiesVery good experience me and my wife in our first time in Panama.
    Feb 21, 2018

    Sortis Hotel, Spa & Casino, Autograph Collection$120

    Sortis Hotel, Spa & Casino, Autograph Collection$120
    Radisson Decapolis Panama City

    Radisson Decapolis Panama City

    Avenida Balboa Con Multicentro, Panama City
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.3 out of 5 (663 reviews)
    Good location and breakfast buffetEnjoyed the opportunity to have a Panamanian food and cultural experience.The
    Apr 18, 2018

    Radisson Decapolis Panama City$92

    Radisson Decapolis Panama City$92
    Hard Rock Hotel Panama Megapolis

    Hard Rock Hotel Panama Megapolis

    Ave. Balboa al lado de Multicentro, Panama City
    • Free Cancellation
    • Reserve now, pay when you stay
    4.5 out of 5.0
     
     
    4.3 out of 5 (2,343 reviews)
    Amazing Experience The staff was amazing and very friendly. We paid for a basic room and got a free upgrade that had a balcony and ocean view. It was like something out of a movie. Will visit again!
    May 17, 2018

    Hard Rock Hotel Panama Megapolis$145

    Hard Rock Hotel Panama Megapolis$145
    Continental Hotel & Casino

    Continental Hotel & Casino

    Via España & Ricardo Arias Street, Panama City
      4.0 out of 5.0
       
       
      3.7 out of 5 (1,056 reviews)
      Nice hotelI’ve stayed in this hotel on a few occasions mostly because of the location. It’s nice and on some websites it can be found at a good price. During this stay there was construction and I didn’t know that before arriving. That being said I would have thought the price would have been better but not ...
      Mar 25, 2018
      Hilton Panama

      Hilton Panama

      Balboa Ave. and Aquilino De La Guardia, Panama City
      • Free Cancellation
      • Reserve now, pay when you stay
      4.5 out of 5.0
       
       
      4.4 out of 5 (314 reviews)
      Great ViewA 4 yr old facility with Great Views, Ocean Front, centrally located
      Mar 20, 2018
      Central Park Hotel & Casino

      Central Park Hotel & Casino

      Calle Miguel Brostella, Panama City
      • Free Cancellation
      • Reserve now, pay when you stay
      3.0 out of 5.0
       
       
      3.7 out of 5 (196 reviews)
      Nice staff, save place and beautifully place nice Close to el dorado, centric and beautifully view secure close to restaurant
      Jan 11, 2018
      The Saba Hotel

      The Saba Hotel

      Panama Internacional zone,Argentina Ave, Panama City
      • Free Cancellation
      3.5 out of 5.0
       
       
      4.0 out of 5 (253 reviews)
      N/AGreat location walking distance and great hotel to stay.
      Jun 4, 2018

      The Saba Hotel$52

      The Saba Hotel$52
      Clarion Victoria Hotel and Suites Panama

      Clarion Victoria Hotel and Suites Panama

      El Cangrejo, Calle D, Bella Vista, Panama City
      • Free Cancellation
      • Reserve now, pay when you stay
      3.5 out of 5.0
       
       
      4.1 out of 5 (631 reviews)
      Very nice , clean hotelThe staff is nice , very nice rooms and very clean
      May 1, 2018

      Clarion Victoria Hotel and Suites Panama$48

      Clarion Victoria Hotel and Suites Panama$48
      Panama Marriott Hotel

      Panama Marriott Hotel

      52nd St. and Ricardo Arias, Panama City
      • Free Cancellation
      • Reserve now, pay when you stay
      4.5 out of 5.0
       
       
      4.4 out of 5 (252 reviews)
      Good location for business tripI was there for a night only. The requested shuttle did not arrive though.
      Apr 11, 2018

      Panama Marriott Hotel$110

      Panama Marriott Hotel$110
      Grand International Hotel

      Grand International Hotel

      Via Argentina Con Calle José Martí, Panama City
      • Free Cancellation
      • Reserve now, pay when you stay
      3.0 out of 5.0
       
       
      3.5 out of 5 (447 reviews)
      Loud construction We heard loud construction the whole time we where there thankfully we only stayed for two nights.
      May 20, 2018
      Hotel El Panama Convention Center & Casino

      Hotel El Panama Convention Center & Casino

      Via Espana 111, Panama City
      • Free Cancellation
      • Reserve now, pay when you stay
      4.0 out of 5.0
       
       
      3.7 out of 5 (449 reviews)
      Nice hotel excellent locationOverall a very good place to stay with family or in a business trip. Located in a center of the city.
      Jun 9, 2018

      Hotel El Panama Convention Center & Casino$78

      Hotel El Panama Convention Center & Casino$78
      Sercotel Panama Princess

      Sercotel Panama Princess

      Calle 53 Marbella y Avenida 5a B sur, Panama City
      • Free Cancellation
      • Reserve now, pay when you stay
      3.5 out of 5.0
       
       
      3.9 out of 5 (456 reviews)
      Inefficient, disinterested staff, but nice hotelWe arrived at the hotel around 7:30 am knowing that we wouldn't be able to check in, no problem. They said they put us on a waiting list to have the room ready as soon as possible, no later than 3 pm. We left and came back around 3:45 pm, had to wait around 20 minutes to talk to staff because they ...
      Apr 27, 2018
      Hotel City House Soloy & Casino

      Hotel City House Soloy & Casino

      Calle 30 con Avenida Peru, Panama City
      • Free Cancellation
      • Reserve now, pay when you stay
      3.0 out of 5.0
       
       
      3.1 out of 5 (97 reviews)
      This hotel is not what it once was.The air coming out of the air conditioning vents in both rooms smells of mold and mildew. The key cards had to be activated every day because they would not allow access to our room so we had to go to the reception desk to activate both cards every day. The reception staff acted like we were annoying ...
      Feb 21, 2018
      Aloft Panama

      Aloft Panama

      Via Israel & Calle 76, Panama City
      • Free Cancellation
      • Reserve now, pay when you stay
      3.5 out of 5.0
       
       
      4.1 out of 5 (210 reviews)
      Not a bad stayThe breakfast buffet was good, but it starts at 6 am and did not always suit my schedule. The first day, I was getting picked up for a day excursion and ordered a box breakfast to go, for pick up at 5:45. When I went to get it, there was no record of the order. The last day, I was headed for the ...
      Feb 1, 2018

      Aloft Panama$90

      Aloft Panama$90
      Sheraton Grand Panama

      Sheraton Grand Panama

      Via Israel And 77th Street, Panama City
      • Free Cancellation
      • Reserve now, pay when you stay
      4.5 out of 5.0
       
       
      4.1 out of 5 (285 reviews)
      Nice and well located hotelFor me it is the best hotel at a 30 minute taxi drive from the international Airport of Tocumen.
      Jun 2, 2018
      Hostal Gemar - Hostel

      Hostal Gemar - Hostel

      El Ingenio, Ave de La Paz, Calle 74, Panama City
        2.5 out of 5.0
         
         
        3.4 out of 5 (20 reviews)
        IT IS A RUNDOWN HOSTAL, 14 ROOMSNO HOT WATER, FINALLY THE LAST DAYS THEY FIX THE WATER HEATER, BROKEN GLASS ON WINDOWS, NO BREAKFAST OR FACILITIES TO GET A CUP OF COFFEE. THE A/C WAS SHUT DOWN EVERY 12 HOURS, NO DOOR ON CLOSET, NO NIGHT STAND LIGHT. NOWHERE TO OPEN THE LUGGAGE
        Mar 9, 2018
        Hotel República

        Hotel República

        Plaza 5 De Mayo Final Ave, Panama City
        • Free Cancellation
        • Reserve now, pay when you stay
        3.5 out of 5.0
         
         
        3.3 out of 5 (59 reviews)
        Excelent !!!The places is clean, all the employees were nice, the guy in the restaurant was nice and friendly, the room clean and the bed comfortable. Also the all the Roms had ac and WiFi . If I got the chance to come back again I’ll stay in this place.
        Feb 21, 2018

        Hotel República$31

        Hotel República$31
        Map

        Recently booked Casinos in Panama City

        Ramada Panama Centro Via Argentina
        3.0 out of 5.0
        Last booking: 26 minutes ago
        Occidental Panamá City by Barceló Hotel Group
        4.0 out of 5.0
        Last booking: 1 hour ago
        Ramada Plaza Panama Punta Pacifica
        4.0 out of 5.0
        Last booking: 1 hour ago
        Novotel Panama City
        4.0 out of 5.0
        Last booking: 2 hours ago
        Eurostars Panama City
        4.0 out of 5.0
        Last booking: 3 hours ago
        The Beach House
        3.0 out of 5.0
        Last booking: 4 hours ago
        Hilton Panama
        4.5 out of 5.0
        Last booking: 4 hours ago
        Sheraton Grand Panama
        4.5 out of 5.0
        Last booking: 4 hours ago
        Principe Hotel and Suites
        3.0 out of 5.0
        Last booking: 4 hours ago

        Feeling lucky? You should, because you're finally going on a well-deserved holiday. Bid farewell to the office, the coworkers, the nagging boss and leave all your worries behind. Take that lucky feeling straight to the tables, slot machines, roulette wheels, and sports books—and straight to Panama City casino hotels.

        It doesn't matter what you're searching for in a vacation trip, Expedia has your back. Expedia has plenty of Panama City casino hotels for you to choose from.

        Find the Best Panama City Casino Hotel

        Are you wondering where the hottest tables are or what Panama City hotel has the best endless buffet? (Winning heaps of money at the tables can really work up an appetite.) Panama City saw a lot of action the year before, and you can find helpful tips in our review section.

        Having said all that, casino hotels in Panama City are a good choice: tons of visitors were highly impressed with their room. So, it should be no surprise guests return again and again, and the locals will treat you like family. In Panama City, you won't have a problem finding fantastic things to do during your vacation.

        Reserve Today

        What is more relaxing than tossing a pair of dice around a felt-lined table while ice-cold refreshments are delivered to you? Nothing, really. Expedia has the grandest offers on Panama City casino hotels so you'll be able to save lots of money on your next vacation. Over the past year, Panama City has seen an increase in interest, so stop wasting time and book your dream adventure now.