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Featured Panama City Boutique Hotels

See all 162 Hotels in Panama City
Villa Palma Boutique Hotel

Villa Palma Boutique Hotel

Calle 1era, Panama City
4.0 out of 5.0
4.2 out of 5 (51 reviews)
Elegant boutique hotelHad zero problems with check in, check out, and overall it was a pleasant experience.
  Oct 9, 2017

$120

$120
DeVille Hotel Boutique

DeVille Hotel Boutique

50 street and Beatriz M. De Cabal, Panama City
4.0 out of 5.0
4.2 out of 5 (273 reviews)
Early check in feeFirst time I've hit this when traveling internationally, if you check in before 3:00 PM there is a $25 fee.
  Oct 31, 2017

$50

$50
Hotel Gatto Blanco & Rooftop Club

Hotel Gatto Blanco & Rooftop Club

Avenida B con Calle 8, Panama City
3.5 out of 5.0
3.3 out of 5 (102 reviews)
Nice hotel for those who like late nights to partyVery clean, very nice staff, however the rooftop bar above the hotel is VERY loud at night and unless you go to bed at 4am on the weekends, you will get little sleep from the noise upstairs. Try staying on the first floor for more silence, bring or ask for earplugs. Management did say that they are ...
  Aug 22, 2017

$72

$72
Global Hotel Panama

Global Hotel Panama

Calle 54 Este y Samuel Lewis, Panama City
4.0 out of 5.0
4.6 out of 5 (132 reviews)
Very Personalized ServiceThe Global Panama is a tucked-away gem that provides a perfect base to explore Panama City and the surrounding areas. Comfortable surroundings, good amenities, excellent food and great drinks, make it an easy spot to linger in, but the staff are the highlight, offering personal service, attention ...
  Oct 23, 2017

$90

$90
Hotel Casa Panamá

Hotel Casa Panamá

Avenida Eloy Alfaro y Calle 11, Panama City
4.0 out of 5.0
3.4 out of 5 (92 reviews)
Modern loft-type rooms, great locationGreat design (though maybe a bit too modern) of the hotel and rooms. AC is perfect as you will need this in Panama. Great location on the edge of Casco viejo. Walking is easy through Casco and you can also go the other way towards the city using the Cinta Costera walkway. Enjoy a small pool on the ...
  Aug 18, 2017

$70

$70
Manrey Boutique Hotel

Manrey Boutique Hotel

Calle Uruguay y Calle 48, Panama City
4.5 out of 5.0
3.8 out of 5 (252 reviews)
Service is goodGreat location for night life. Several Discos and nice restruant walking distance.
  Oct 19, 2015
Occidental Panamá City

Occidental Panamá City

Avenida 2da Sur, Obarrio, Bella Vista, Panama City
4.0 out of 5.0
4.1 out of 5 (673 reviews)
Nice Hotel & Great Location.I always stay here when in the city, great staff, comfortable room and located around shopping with the metro down the block. The breakfuss is always good.
  Nov 2, 2017

$54

$54
Toscana Inn Hotel

Toscana Inn Hotel

Calle D, El Cangrejo, Bella Vista, Panama City
3.5 out of 5.0
4.5 out of 5 (547 reviews)
Very convenient We enjoyed the breakfast and location. There are good restaurants in the area and the staff was truly excellent Would recommend this hotel above any of the others in this area. I was traveling with a group of friends who were first time visitors so Luis the hotel driver took us on great tours of ...
  Aug 23, 2017

$75

$75
Las Clementinas

Las Clementinas

Casco Antiguo, Calle 11 Y Ave B, Panama City
3.5 out of 5.0
4.8 out of 5 (31 reviews)
Wonderful quaint hotel in the middle of everythingFantastic location. In the middle of everything yet is was quiet and it even has parking for your rental car! The rooms felt like I was back in Europe. If you want modern and fancy, this is not your place. If you want quaint, authentic, clean and comfortable, this is for you!
  Apr 19, 2016
Bristol Panama

Bristol Panama

Avenida Aquilino de La Guardia, Panama City
5.0 out of 5.0
4.6 out of 5 (388 reviews)
Always good and will always recommend.This hotel with out a doubt is a hidden jewel. It's close to everything the staff is so friendly. I've been coming here very often and cannot think of staying anywhere else.
  Nov 6, 2017

$127

$127
American Trade Hotel

American Trade Hotel

Plaza Herrera Casco Viejo, Panama City
4.5 out of 5.0
4.7 out of 5 (112 reviews)
Characterful HotelVery nice hotel in picturesque / quiet part of Panama City. Within walking distance of all the main sites of interest in Casco Viejo.
  Nov 14, 2017

$260

$260
Riande Granada Urban Hotel

Riande Granada Urban Hotel

El Cangrejo; Calle Eusebio A, Morales, Panama City
3.5 out of 5.0
4.0 out of 5 (379 reviews)
Wow Panama The hotel was in a good location. Free breakfast. Awesome shower. Bed was comfortable.
  Nov 6, 2017

$83

$83
Tantalo Hotel / Kitchen / Roofbar

Tantalo Hotel / Kitchen / Roofbar

Calle 8 Este con Avenida B, Casco Viejo, Panama City
3.5 out of 5.0
4.1 out of 5 (53 reviews)
Great hotelHotel was a great location, rooftop bar was amazing, food and drinks were great. The only issue I had was with the front desk girl, every encounter with her was unpleasant.
  Oct 28, 2017

$99

$99
The Saba Hotel

The Saba Hotel

Panama Internacional zone,Argentina Ave, Panama City
3.5 out of 5.0
4.1 out of 5 (186 reviews)
A jewel of a boutique hotel!When we first arrived I had my reservations about staying because the lobby furniture looked grungy and peeping around the corner at the restaurant it looked out dated and in need of a facelift. Once on the elevator and in the room I put my guards down. The room and bathroom was very well appointed ...
  Oct 8, 2017

$47

$47
Radisson Decapolis Panama City

Radisson Decapolis Panama City

Avenida Balboa Con Multicentro, Panama City
4.0 out of 5.0
4.4 out of 5 (583 reviews)
Great overnight stayStaff is really helpful and provided excellent service. Great breakfast with lots of choices included with the room. The room was nice but the beds were hard and not very comfortable. The hotel restaurant is very nice and had a great dinner. The hotel has a walkway to a 4 story mall if you want to ...
  Nov 16, 2017

$98

$98
Map

Recently booked Boutique Hotels in Panama City

Sortis Hotel, Spa & Casino, Autograph Collection
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Hard Rock Hotel Panama Megapolis
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Novotel Panama City
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Last booking: 1 hour ago
Crowne Plaza Panama Airport
4.0 out of 5.0
Last booking: 1 hour ago
AC Hotel by Marriott Panama City
3.5 out of 5.0
Last booking: 1 hour ago
Riande Aeropuerto Hotel & Casino
4.0 out of 5.0
Last booking: 3 hours ago
Veneto Hotel & Casino
3.5 out of 5.0
Last booking: 3 hours ago

Book a Panama City Boutique Lodging that is Especially You

Wherever you might visit, you always take your exceptional self with you, and Expedia offers bookings at the most fashionable and distinctive designer rooms in the area. Landing in Panama City and discover that all your concerns are left behind, you can relax for the next few days. Take a deep breath when you stroll out of the airport and inhale the fabulous sensation of answering to nobody. With so much to see in Panama City it continues to be a popular place to vacation.

Petite Lodging with Tons of Personality

You'll love returning from a thrilling day of sightseeing in Panama City and unwinding in a room that boasts quirky touches and inviting artistic pieces. Moreover, these distinctive hotels bring a bit of the essence and vibe of Panama City into your room, making your stay that much more personal. The majority of boutique hotels have characteristics like:

  • An idiosyncratic style that you won't find in larger hotels, from individually configured rooms to cozy gathering areas, and creature comforts that make them feel extremely comfortable.
  • A more exclusive stay, since boutique hotels commonly have fewer than a hundred rooms.
  • A highly personalized type of service, where they add thoughtful touches like fresh flowers.
  • A desired address in the center of the city. You'll be just steps away from the area's coolest venues.

Indulge in Everything Panama City Offers!

Panama City has rooms to please most anyone that that create a visit memorable.

Stay in Style While in Panama City

Your Panama City boutique hotel is just a few taps away. From hotels that embrace the city's time-honored traditions to ones that flaunt conventions, you are sure to getan accommodation that suits you. Expedia makes it no problem to pick your perfect place to stay when you vacation in Panama City.