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Featured Panama Boutique Hotels

See all 517 Hotels in Panama
DeVille Hotel Boutique

DeVille Hotel Boutique

50 street and Beatriz M. De Cabal, Panama City
4.5 out of 5.0
4.2 out of 5 (286 reviews)
Good location, Quiet HotelThis is a small hotel with kind and helpful staff. It's close to lots of restaurants and the Metro. The rooms are spacious and comfortable.
  Jan 5, 2018

$66

$66
Villa Palma Boutique Hotel

Villa Palma Boutique Hotel

Calle 1era, Panama City
4.5 out of 5.0
4.3 out of 5 (59 reviews)
Upscale boutique hotel It's our second time staying at this hotel. It has a great roof top. lounge. Rooms are cute and staff were very friendly and helpful.
  Jan 7, 2018

$119

$119
Global Hotel Panama

Global Hotel Panama

Calle 54 Este y Samuel Lewis, Panama City
4.5 out of 5.0
4.6 out of 5 (140 reviews)
Comfortable and economical This hotel is in the financial district, so no beach views. It is very comfortable, with a wonderful staff. The restaurant in the hotel is very good, but there are several others within walking distance. The waterfront is also within walking distance, but taxis and Ubers are plentiful and easy.
  Jan 10, 2018

$95

$95
Hotel Gatto Blanco & Rooftop Club

Hotel Gatto Blanco & Rooftop Club

Avenida B con Calle 8, Panama City
3.5 out of 5.0
3.2 out of 5 (106 reviews)
Like everyone says, you must tolerate loud musicPrice is right. Think of the loud music beat as a heartbeat that last until 2-3 am. If you can do that and fall asleep, the hotel is a good deal for its location.
  Jan 8, 2018

$94

$94
Los Establos Boutique Hotel

Los Establos Boutique Hotel

Jaramillo Arriba, Boquete
3.5 out of 5.0
4.3 out of 5 (7 reviews)
Our family stayed at Los Establos for 3 nights and enjoyed our stay. Clean, quiet and very friendly staff.
  Apr 5, 2017

$386

$386
Playa Tortuga Hotel Beach And Resort

Playa Tortuga Hotel Beach And Resort

Camino A Playa Bluff Y P Creek, Bocas Del Toro
4.5 out of 5.0
3.6 out of 5 (289 reviews)
Beautiful place good place for relaxing excellent Beautiful place excellent food the staff amazing and the hotel is located in the right place . THANKS PLAYA TORTUGA,PANAMA.
  Dec 5, 2017

$143

$143
Bristol Panama

Bristol Panama

Avenida Aquilino de La Guardia, Panama City
5.0 out of 5.0
4.6 out of 5 (416 reviews)
Urban OasisFrom our admittedly limited experience of Panama City, it is a mix of splendor and squalor. The Bristol is a nice place to come home to after exploring the city. Our room is very nice and extremely comfortable.
  Jan 15, 2018

$169

$169
Hotel Casa Panamá

Hotel Casa Panamá

Avenida Eloy Alfaro y Calle 11, Panama City
4.5 out of 5.0
3.5 out of 5 (102 reviews)
One night is Casco ViejoThe hotel staff was extremely friendly and accommodating. Nice cute hotel
  Jan 7, 2018

$114

$114
The Haven and Spa

The Haven and Spa

Avenida A Oeste, Bajo, Boquete
4.0 out of 5.0
4.3 out of 5 (117 reviews)
Overall excellent Overall excellent. Clean room. Grounds well kept. Well managed
  Feb 4, 2017

$139

$139
The Saba Hotel

The Saba Hotel

Panama Internacional zone,Argentina Ave, Panama City
4.0 out of 5.0
4.1 out of 5 (200 reviews)
Bathroom tipIt was a good experiences be the time to Ben calm and sleep very good at the hotel , just be sure all the rooms has their warm water on the showers in good conditions or take the time to explain your costumers how it work otherwise everything is great, the saving light thing with the card, good sheets ...
  Jan 16, 2018

$47

$47
The Riverside Inn

The Riverside Inn

11 de Abril, Boquete
4.0 out of 5.0
4.8 out of 5 (53 reviews)
A true respiteLovely accommodations, HUGE rooms, friendly staff, great breakfast. We also enjoyed the location, just a few minutes out of the hustle and bustle of Boquetr
  Aug 24, 2017

$135

$135
Manrey Boutique Hotel

Manrey Boutique Hotel

Calle Uruguay y Calle 48, Panama City
5.0 out of 5.0
3.8 out of 5 (252 reviews)
Service is goodGreat location for night life. Several Discos and nice restruant walking distance.
  Oct 19, 2015
Occidental Panamá City

Occidental Panamá City

Avenida 2da Sur, Obarrio, Bella Vista, Panama City
4.5 out of 5.0
4.1 out of 5 (717 reviews)
Good location and confortThis hotel is located very close to the main shopping mall and areas of Panama City. They have a good rooftop and also the room and hotel staff are great. Price is very affordable
  Jan 12, 2018

$67

$67
American Trade Hotel

American Trade Hotel

Plaza Herrera Casco Viejo, Panama City
5.0 out of 5.0
4.6 out of 5 (114 reviews)
Lovely and ultra comfortable hotel in the heart of Old Town.
  Nov 27, 2017

$260

$260
Toscana Inn Hotel

Toscana Inn Hotel

Calle D, El Cangrejo, Bella Vista, Panama City
3.5 out of 5.0
4.5 out of 5 (549 reviews)
Very nice accommodations. good location. very nice staff
  Jan 4, 2018

$80

$80
Las Clementinas

Las Clementinas

Casco Antiguo, Calle 11 Y Ave B, Panama City
4.0 out of 5.0
4.8 out of 5 (31 reviews)
Wonderful quaint hotel in the middle of everythingFantastic location. In the middle of everything yet is was quiet and it even has parking for your rental car! The rooms felt like I was back in Europe. If you want modern and fancy, this is not your place. If you want quaint, authentic, clean and comfortable, this is for you!
  Apr 19, 2016
Riande Granada Urban Hotel

Riande Granada Urban Hotel

El Cangrejo; Calle Eusebio A, Morales, Panama City
4.0 out of 5.0
4.0 out of 5 (392 reviews)
Unique and ArtfulThis is very well designed hotel. There are different unique artful pieces all over.The bathroom near the pool is a very artistic. Let me get down to basic details. Check In was smooth. My initial room did not have a WiiFi signal, so my room was changed with no hassle. The water can become very hot, ...
  Jan 5, 2018

$72

$72
Bocas del Mar Hotel

Bocas del Mar Hotel

Road to Boca Chica, Boca Chica
4.5 out of 5.0
4.8 out of 5 (78 reviews)
5 Star in the real PanamaThis property was amazing...better than expected and much needed. Our bed was extremely comfortable, the bathroom was amazing, and the 2 pools are very clean and have views of the beaches. The owner and staff went out of their way to keep the kitchen open late for a 5 star serviced beautiful meal ...
  Oct 1, 2017

$189

$189
Tantalo Hotel / Kitchen / Roofbar

Tantalo Hotel / Kitchen / Roofbar

Calle 8 Este con Avenida B, Casco Viejo, Panama City
4.0 out of 5.0
4.1 out of 5 (57 reviews)
Trendy HotelTantalo is located just inside Casco Antiguo near Casco’s entrance. Restaurant is very popular and the rooftop bar is the largest I have seen. Several restaurants nearby feature rooftop settings, as well. That said guest rooms, particularly those on the north corner can hear music and traffic until ...
  Nov 26, 2017

$139

$139
Map

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Book a Panama Boutique Lodging that is Especially You

Arriving in Panama you'll discover that all your concerns are left behind and you can rest easy for the next several days. And you're not alone in thinking it is a nice idea to come to Panama, as this location has seen a large upsurge in travelers this past year. It should come as no shock that Panama is popular with travelers such as yourself, since it ranks in our top 100 of most visited vacation destinations. No matter where you may holiday, you always pack your one-of-a-kind self on your trip, and Expedia provides reservations at the most fashionable and distinctive boutique rooms in the city.

Petite Hotel with Enormous Personality

You'll love returning from a thrilling day of sightseeing in Panama and decompressing in a room that boasts inviting architectural designs and fabulous artwork. Further, these distinctive properties bring a bit of the spirit and vibe of Panama into your room, making your stay much more intimate. The majority of boutique hotels have qualities like:

  • A highly personalized service where they add thoughtful touches like fresh flowers.
  • A more exclusive stay, since boutique hotels commonly have fewer than 100 rooms.
  • A desirable address in the entertaining part of the city. You'll be steps from the city's most talked about attractions.
  • An idiosyncratic character that you will not be able to get in more sizable hotels, from individually crafted rooms to intimate bars, and thoughtful touches that make it feel like home.

Bask in Everything Panama Offers!

Panama has rooms to satisfy all types of budgets and preferences that create a visit extraordinary.

Book a Room with Views Inside and Out in Panama

If you need a stay in a Panama boutique hotel that will make you feel like a guest in a chic home, book soon, since everybody is as well. Luckily, Expedia has all the top listings on the most exceptional boutique properties. A remarkable stay is only a couple taps away!