Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Panama Independent Hotels

See all 499 Hotels in Panama
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Vía Tocumen, Tocumen
4.5 out of 5.0
4.0 out of 5 (1,825 reviews)
Very clean and ver close and easy to get to from the airport. I also had a very good burger at the … - 

$86

$86
Central Hotel Panama

Central Hotel Panama

Plaza de la Independencia Casco Viejo, Panama City
4.5 out of 5.0
4.2 out of 5 (56 reviews)
Newly refurbished and great location In the heart of Casca Viejo one of the oldest hotels in Panama was redurbished and reopened in 2016 … - 

$146

$146
Veneto Hotel & Casino

Veneto Hotel & Casino

Eusebio A Morales Ave And Via Veneto Str, Panama City
3.0 out of 5.0
3.3 out of 5 (1,361 reviews)
Vento Hotel is excellent Casino and Hotel I was able to visit the Panama Canal , which is 15 minutes from the Veneta Hotel. There are plenty … - 

$60

$60
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Italy Avenue, Punta Paitilla, Panama City
4.0 out of 5.0
3.9 out of 5 (580 reviews)
Excellent stay! Awesome staff and very close to many amenities in the downtown area. Would stay her … - 

$75

$75
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Av. Balboa con Calle 53, Panama City
4.5 out of 5.0
4.4 out of 5 (112 reviews)
Centrally located Very nice hotel centrally located with lots of view. The staff were very nice, helpful and a few of … - 

$124

$124
The Saba Hotel

The Saba Hotel

Panama Internacional zone,Argentina Ave, Panama City
4.0 out of 5.0
4.1 out of 5 (193 reviews)
Very clean! Love the scent in the lobby Service on point, non xpensive! - 

$47

$47
Hotel Terranova

Hotel Terranova

Calle 49 Bella Vista, Panama City
3.5 out of 5.0
3.1 out of 5 (206 reviews)
An cheap hotel near the center of the city We stayed at this hotel because we needed a hotel near the center of the city and we wanted to save … - 

$38

$38
Global Hotel Panama

Global Hotel Panama

Calle 54 Este y Samuel Lewis, Panama City
4.5 out of 5.0
4.6 out of 5 (136 reviews)
Bathrooms give little if any Privacy! Bathroom lacks privacy. I don’t want to type anything else. - 

$95

$95
Hotel El Parador

Hotel El Parador

Eusebio Morales Ave, Panama City
3.5 out of 5.0
3.0 out of 5 (255 reviews)
Is ok Very nice went canal tour the city and shop The restaurant staff very helpfull - 

$35

$35
Express Inn Panama International Airport Hostel

Express Inn Panama International Airport Hostel

Calle Enrique Malek, Tocumen
2.0 out of 5.0
2.6 out of 5 (94 reviews)
Good Hotel for sleeping in PTY If you are looking to sleep in a hotel near PTY Airport and you are under a budget this is the plac … - 

$50

$50
Hotel Coral Suites

Hotel Coral Suites

Calle D El Cangrejo, Panama City
4.0 out of 5.0
4.3 out of 5 (358 reviews)
Good value Very centrally located for shopping, restaurants and the metro. Rooms are large with a full kitchen … - 

$62

$62
Aranjuez Hotel & Suites

Aranjuez Hotel & Suites

Avenida Red Gray, David
4.0 out of 5.0
4.4 out of 5 (119 reviews)
Panama - Aranjuez in David Staff and Hotel Wonderful. We stayed 3 times during our tour of the Chiquiri area in Panama. We kne … - 

$85

$85
Playa Blanca Beach Resort All Inclusive

Playa Blanca Beach Resort All Inclusive

115 Km Via Interamericana, Rio Hato
3.5 out of 5.0
3.5 out of 5 (333 reviews)
Nice, friendly resort 4 of us stayed at the resort from October 30 - November 2 to break up our 10 day trip to Panama Cit … - 

$178

$178
DeVille Hotel Boutique

DeVille Hotel Boutique

50 street and Beatriz M. De Cabal, Panama City
4.5 out of 5.0
4.2 out of 5 (278 reviews)
Early check in fee First time I've hit this when traveling internationally, if you check in before 3:00 PM there is a … - 

$50

$50
Royal Decameron Golf, Beach Resort and Villas All Inclusive

Royal Decameron Golf, Beach Resort and Villas All Inclusive

KM 115 Carretera, Rio Hato
4.0 out of 5.0
3.6 out of 5 (543 reviews)
We had a great time, but... The fact that the staff was pleasant made the stay great, but the large language barrier made it di … - 

$246

$246
Red Frog Beach Island Resort

Red Frog Beach Island Resort

Isla Bastimentos, Isla Bastimentos
4.5 out of 5.0
4.3 out of 5 (67 reviews)
You're missing boat Reg Frog This property could be and should be the king of resorts in the Boca Del Toro's. Unfortunately, the … - 
Hotel Ojos del Rio

Hotel Ojos del Rio

calle 41 este, Panama City
3.5 out of 5.0
4.0 out of 5 (251 reviews)
Well located and comfortable hotel The hotel has cosy, comfortable rooms. Everything is clean and nicely decorated. Breakfast is good. … - 

$44

$44
Playa Tortuga Hotel Beach And Resort

Playa Tortuga Hotel Beach And Resort

Camino A Playa Bluff Y P Creek, Bocas Del Toro
4.5 out of 5.0
3.6 out of 5 (283 reviews)
Beautiful place good place for relaxing excellent Beautiful place excellent food the staff amazing and the hotel is located in the right place . THAN … - 

$125

$125
Hotel Bahia Suites

Hotel Bahia Suites

Calle 31, Justo Arosamena, Panama City
4.0 out of 5.0
3.3 out of 5 (383 reviews)
No hot water in shower. Second time visiting and the first was great so I guess the hotel had an of … - 

$45

$45
Hotel Benidorm Panama

Hotel Benidorm Panama

Av Peru Y Calle 29, Panama City
3.0 out of 5.0
2.8 out of 5 (76 reviews)
Good garage parking Good customer service but rooms are alright not too fancy. However for the price its good - 

$31

$31
Map

Recently booked Panama hotels

Occidental Panamá City
4.5 out of 5.0
Last booking: 31 minutes ago
Radisson Summit Hotel and Golf Panama
4.5 out of 5.0
Last booking: 36 minutes ago
Aloft Panama
4.0 out of 5.0
Last booking: 5 hours ago
Trump International Hotel and Tower Panama
5.0 out of 5.0
Last booking: 8 hours ago
Country Inn & Suites By Carlson Panama Canal
4.0 out of 5.0
Last booking: 9 hours ago
Torre de Alba Hotel & Suites
4.0 out of 5.0
Last booking: 10 hours ago
Hotel Ojos del Rio
3.5 out of 5.0
Last booking: 11 hours ago
Waldorf Astoria Panama
5.0 out of 5.0
Last booking: 11 hours ago
Hard Rock Hotel Panama Megapolis
5.0 out of 5.0
Last booking: 11 hours ago

Independent Panama Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Panama, Panama. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Panama hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Panama Independent locations may even offer extra little benefits and discounts for frequent travelers.