Beginning of main content

Panama Hotel Rooms at the Independent

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Panama Hotels

Search Flight + Hotel

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Panama Independent Hotels

See all 478 Hotels in Panama
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Vía Tocumen, Tocumen
4.0 out of 5.0
3.8 out of 5 (624 reviews)
Nice hotel, close to the airport. This hotel is far more than the average airport hotel. It has many qualities of a resort and offers … - 

$88

$88
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Italy Avenue, Punta Paitilla, Panama City
3.5 out of 5.0
3.8 out of 5 (154 reviews)
Great view Our room was very clean and it had a great view. The hotel was older but it had nice features to ma … - 

$71

$71
Crowne Plaza Panama Airport

Crowne Plaza Panama Airport

Ave. Domingo Diaz, Tocumen
4.0 out of 5.0
4.3 out of 5 (147 reviews)
Nice hotel... Nice hotel.... but have to wait to long for the shuttle - 

$104

$104
Eurostars Panama City

Eurostars Panama City

Calle Ricardo Arias, Panama City
4.0 out of 5.0
3.9 out of 5 (129 reviews)
VERY NICE HOTEL GOOD STAY AT THE HOTEL CLEAN AND NICE,ME & WIFE LOVE IT - 

$54

$54
Occidental Panamá City

Occidental Panamá City

Avenida 2da Sur, Obarrio, Bella Vista, Panama City
4.0 out of 5.0
3.9 out of 5 (221 reviews)
A good nights rest I checked in and got a good nights rest.. The hotel was clean. The neighborhood was okay. The staff … - 

$51

$51
Sheraton Bijao Beach Resort - All Inclusive

Sheraton Bijao Beach Resort - All Inclusive

Carretera Interamericana km 108, Rio Hato
4.0 out of 5.0
3.6 out of 5 (198 reviews)
Nice hotel for kids. Staff was very friendly all the time. Even though it was ok, they need to impr … - 

$138

$138
Country Inn & Suites By Carlson Panama Canal

Country Inn & Suites By Carlson Panama Canal

Amador Ave & Pelicano Ave, Panama City
3.5 out of 5.0
4.0 out of 5 (413 reviews)
Good location. Great hotel to start our trip towards Santa Catalina and then onwards to Boca Chica! Lovely pool, o … - 

$68

$68
Hyatt Place Panama City/Downtown

Hyatt Place Panama City/Downtown

Avenida Aquilino de la Guardia, between, Panama City
3.5 out of 5.0
4.6 out of 5 (313 reviews)
Great Hotel in Centro Thanks for a wonderful week! Your staff was welcoming and extremely helpful in setting up taxis and … - 

$83

$83
Veneto Hotel & Casino

Veneto Hotel & Casino

Eusebio A Morales Ave And Via Veneto Str, Panama City
3.5 out of 5.0
3.1 out of 5 (486 reviews)
Nice hotel. Close to everything. Great stay. Hotel geared for gentleman, not for children. The hotel is very safe. Staff is very fri … - 

$56

$56
Country Inn & Suites Panama City

Country Inn & Suites Panama City

Blvd El Dorado Calle 23 1/2B N, Panama City
3.0 out of 5.0
3.9 out of 5 (162 reviews)
Close to many restaurants The room is clean and good service. The staff are friendly and kind. - 

$60

$60
Map

Recently booked Panama hotels

Hotel El Parador
3.0 out of 5.0
Last booking: 10 minutes ago
Panama Marriott Hotel
4.0 out of 5.0
Last booking: 11 minutes ago
Trump Ocean Club International Hotel and Tower Panama
5.0 out of 5.0
Last booking: 31 minutes ago
Hyatt Place Panama City/Downtown
3.5 out of 5.0
Last booking: 45 minutes ago
Sheraton Bijao Beach Resort - All Inclusive
4.0 out of 5.0
Last booking: 1 hour ago
Hard Rock Hotel Panama Megapolis
4.5 out of 5.0
Last booking: 1 hour ago
Express Inn Panama International Airport Hostel
1.5 out of 5.0
Last booking: 1 hour ago
Sortis Hotel, Spa & Casino, Autograph Collection
4.5 out of 5.0
Last booking: 1 hour ago
La Cresta Inn
3.5 out of 5.0
Last booking: 1 hour ago

Independent Panama Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Panama, Panama. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Panama hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Panama Independent locations may even offer extra little benefits and discounts for frequent travelers.