Beginning of main content

location Panama is highly rated for Cafes and Shopping by 2,412 people

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Panama

Tonight Tonight May 20 - May 21
This weekend This weekend May 25 - May 27
Next weekend Next weekend Jun 1 - Jun 3

Top 10 Hotels in Panama

Innfiniti Hotel & Suites

Innfiniti Hotel & Suites

Calle 33 Este a 100 mts de Ave Balboa, Panama City
    3.5 out of 5.0
     
     

    Situated in Calidonia, this hotel is close to National Bank House Museum, Metropolitan Cathedral of Panama, and Museum of Natural Science. Also nearby are Avenida ...

    Innfiniti Hotel & Suites$58

    Innfiniti Hotel & Suites$58
    Wyndham Panama Albrook Mall

    Wyndham Panama Albrook Mall

    Ave. Marginal, Corregimiento de Ancon, Panama City
      4.0 out of 5.0
       
       

      Located in the heart of Panama City, this hotel is within 1 mi (2 km) of Albrook Shopping Mall and Anthropological Museum Reina Torres de Arauz. Metropolitan ...

      Wyndham Panama Albrook Mall$104

      Wyndham Panama Albrook Mall$104
      RIU Plaza Panama

      RIU Plaza Panama

      Calle 50, Urb. Marbella, Panama City
        4.0 out of 5.0
         
         

        Located in the heart of Bella Vista, this spa hotel is within 3 mi (5 km) of Museum of Natural Science, Metropolitan Cathedral of Panama, and Museum of History ...

        RIU Plaza Panama$86

        RIU Plaza Panama$86
        The Bahia Grand Hotel

        The Bahia Grand Hotel

        Punta Colon Street, Panama City
          5.0 out of 5.0
           
           

          Situated in the city center, this luxury hotel is close to Multicentro Panama, Multiplaza Pacific Mall, and Megapolis Convention Center. Also nearby are ATLAPA ...

          The Bahia Grand Hotel$139

          The Bahia Grand Hotel$139
          TRYP by Wyndham Panamá Centro

          TRYP by Wyndham Panamá Centro

          Via Veneto, El Cangrejo Bellavista, Panama City
            3.5 out of 5.0
             
             

            Located in El Cangrejo, this hotel is 0.5 mi (0.8 km) from Via Espana and 2.8 mi (4.6 km) from Metropolitan Cathedral of Panama. National Shrine of the Heart ...

            TRYP by Wyndham Panamá Centro$48

            TRYP by Wyndham Panamá Centro$48
            Central Hotel Panama

            Central Hotel Panama

            Plaza de la Independencia Casco Viejo, Panama City
              4.0 out of 5.0
               
               

              Located in Casco Viejo, this hotel is steps from Interoceanic Canal Museum, Independence Square, and Metropolitan Cathedral of Panama.

              Central Hotel Panama$119

              Central Hotel Panama$119
              Bristol Panama

              Bristol Panama

              Avenida Aquilino de La Guardia, Panama City
                5.0 out of 5.0
                 
                 

                Located in the heart of Bella Vista, this luxury hotel is 0.3 mi (0.4 km) from Via Espana and 2.6 mi (4.2 km) from Metropolitan Cathedral of Panama. National ...

                Bristol Panama$82

                Bristol Panama$82
                Riande Aeropuerto Hotel & Casino

                Riande Aeropuerto Hotel & Casino

                Vía Tocumen, Tocumen
                  4.0 out of 5.0
                   
                   

                  Just 1 mile (1.6 km) from the airport, this Panama City hotel is 5 minutes from the shopping center Shopping Metro Mall and 10 minutes from the ruins of Panamá ...

                  Riande Aeropuerto Hotel & Casino$91

                  Riande Aeropuerto Hotel & Casino$91
                  Country Inn & Suites by Radisson, Panama Canal, Panama

                  Country Inn & Suites by Radisson, Panama Canal, Panama

                  Amador Ave & Pelicano Ave, Panama City
                    3.5 out of 5.0
                     
                     

                    At the entrance of the Panama Canal, close to Smithsonian’s Tropical Research Institute, Bridge of the Americas, and Panama Old Quarters. This business-friendly ...

                    Country Inn & Suites by Radisson, Panama Canal, Panama$75

                    Country Inn & Suites by Radisson, Panama Canal, Panama$75
                    Hard Rock Hotel Panama Megapolis

                    Hard Rock Hotel Panama Megapolis

                    Ave. Balboa al lado de Multicentro, Panama City
                      4.5 out of 5.0
                       
                       

                      This family-friendly Panama City hotel is located by the ocean, within 1 mi (2 km) of Multicentro Panama and Via Espana. Multiplaza Pacific Mall is 1.8 mi (2.9 ...

                      Hard Rock Hotel Panama Megapolis$140

                      Hard Rock Hotel Panama Megapolis$140
                      Map

                      What are the top landmarks in Panama?

                      Don’t miss these must-see sights and attractions

                      Best neighborhoods to visit in Panama

                      Get a lay of the land and find the perfect place to stay

                      Recent Reviews in Panama