The best area to stay in Pedro A Santos is along the main highway, Highway 307, particularly near the town center.
This area provides convenient access to local eateries and shops, and it's a practical base for exploring the region. You'll find a concentration of accommodations and services along this route, making it easy to navigate and find what you need.
For couples seeking a quiet and convenient stay, accommodations directly on Highway 307 offer easy access to nearby attractions like the Mayan ruins and cenotes, which are often just a short drive away.