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Top San Antonio Neighborhoods for Luxury Hotels

Featured San Antonio Luxury Hotels

See all 512 Hotels in San Antonio
Mokara Hotel & Spa San Antonio

Mokara Hotel & Spa San Antonio

212 W Crockett Street, San Antonio
4.5 out of 5.0
4.8 out of 5 (911 reviews)
Great accommodationWe booked the weekend for our 27th anniversary and upon arrival we were upgraded to a larger suite. They brought us champagne, a bouquet of roses and chocolate covered strawberries! What a treat! They went above and beyond to make this a special weekend for my husband and I.
  Nov 6, 2017

$271

$271
Eilan Hotel & Spa, Autograph Collection

Eilan Hotel & Spa, Autograph Collection

18603 La Cantera Terrace, San Antonio
4.5 out of 5.0
4.5 out of 5 (562 reviews)
AMAZING!This is one of the most beautiful hotels I have stayed in. Very dramatic entry. The staff was very helpful and my stay was perfection. I will definitely stay here again. Thank you.
  Nov 16, 2017

$152

$152
The St. Anthony, A Luxury Collection Hotel, San Antonio

The St. Anthony, A Luxury Collection Hotel, San Antonio

300 E Travis St, San Antonio
5.0 out of 5.0
4.6 out of 5 (285 reviews)
The hotel was beautiful, and the staff was excellent. We were disappointed in the breakfast buffett.
  Nov 14, 2017

$169

$169
JW Marriott San Antonio Hill Country Resort & Spa

JW Marriott San Antonio Hill Country Resort & Spa

23808 Resort Pkwy, San Antonio
4.5 out of 5.0
4.6 out of 5 (497 reviews)
Best Texas Hill Country ExperienceFrom the entrance, this place was beautifully decorated for the Holidays! Then every person that attended to check-in to service in the restaurant were superb! The room was spaciously laid-out with luxurious touches everywhere!
  Nov 21, 2017

$169

$169
Alamo Lodge

Alamo Lodge

1126 E Elmira St, San Antonio
1.5 out of 5 (6 reviews)
It's cheapWe got what we paid for, a cheap motel. Not too bad but wife didn't like it. It was kind of hard to find. One of the beds seemed like a slat was missing. Pool was clean.
  Jun 9, 2010
Brackenridge House Bed & Breakfast

Brackenridge House Bed & Breakfast

230 Madison, San Antonio
4.5 out of 5.0
4.8 out of 5 (40 reviews)
A Wonderful B&B We had a great stay. It is an easy & safe walk to the Riverwalk area of San Antonio. The room was very nice and comfortable. The breakfasts were very good. I will stay there again on our next trip to San Antonio.
  Sep 28, 2017
Hotel Emma

Hotel Emma

136 E Grayson, San Antonio
4.5 out of 5.0
4.8 out of 5 (128 reviews)
Unique hotel near city centerA truly unique and deluxe experience! This hotel is a destination in itself. The wonderful staff at Hotel Emma strived to make our anniversary special and enjoyable and they succeeded! We look forward to coming back some day with our family and enjoying Hotel Emma and the vibrant Pearl campus ...
  Nov 8, 2017

$335

$335
Hotel Contessa - Luxury Suites on the Riverwalk

Hotel Contessa - Luxury Suites on the Riverwalk

306 W Market Street, San Antonio
4.0 out of 5.0
4.6 out of 5 (7,711 reviews)
Front desk staff is incredibly courteous and helpful.
  Nov 21, 2017

$135

$135
Menger Hotel

Menger Hotel

204 Alamo Plaza, San Antonio
3.5 out of 5.0
4.1 out of 5 (4,654 reviews)
Nice place.Easy access to River Walk. Enjoyed the ambience of an historic hotel. Very nice staff. Room was poorly lit but we were provided with an additional lamp upon request.
  Nov 19, 2017

$132

$132
Grand Hyatt San Antonio

Grand Hyatt San Antonio

600 E Market St, San Antonio
4.0 out of 5.0
4.4 out of 5 (4,730 reviews)
Downtown San Antonio on the riverwalk.Disappointed in maid service. We had spill on the bed. We had place towels on it to try to absorb. Maid , just made up the bed did not trade out sheets. Front office sent two people up to change, one brought the sheets in and left. My wife helped the other person makeup the bed. She was nice enough, ...
  Nov 13, 2017

$129

$129
Wyndham San Antonio Riverwalk

Wyndham San Antonio Riverwalk

111 E Pecan St, San Antonio
4.0 out of 5.0
3.7 out of 5 (3,112 reviews)
Nice hotel, would stay again. Great value.Enjoyed my time in San Antonio. I would have liked the hot tub, but it was under construction.
  Nov 20, 2017

$129

$129
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

150 E Houston St, San Antonio
4.0 out of 5.0
4.3 out of 5 (4,230 reviews)
On the riverwalk but our room faced the streetBrought BF from Montana here to experience the river walk, Alamo, Market place and great Mexican food. No microwave in room so left over Mexican food I brought back was wasted. Beautiful hotel and smells amazing when you walk in. Staff friendly but you do have to pay for Valet parking as there is ...
  Nov 22, 2017

$130

$130
Omni La Mansion del Rio

Omni La Mansion del Rio

112 College St, San Antonio
4.0 out of 5.0
4.3 out of 5 (3,806 reviews)
RELAXING WEEKWE WENT TO SAN ANTONIO FOR A QUITE AND ENJOYED OUR STAY.
  Nov 15, 2017

$169

$169
Hyatt Regency San Antonio Riverwalk

Hyatt Regency San Antonio Riverwalk

123 Losoya St, San Antonio
4.0 out of 5.0
4.5 out of 5 (5,233 reviews)
Great location. Fantastic staff.Beautiful place to stay. Unfortunately our bathtub backed up the very first night. A lock on the door was broken and the bed was very firm. Besides that it was a beautiful place to stay and the staff is amazing. On the plus side it was extremely clean And felt very safe.
  Nov 21, 2017

$149

$149
La Quinta Inn San Antonio Lackland

La Quinta Inn San Antonio Lackland

6511 W Military Dr, San Antonio
2.5 out of 5.0
3.4 out of 5 (1,403 reviews)
Wonderful location to Lackland Air Force Base. Fantastic hotel if you're visiting Lackland AFB and can't stay on base. Literally turn right out of hotel and turn left at the first light and you're at the gate. At check in, Charlotte whips out a map and highlighter and gives you directions to the graduation events. She is an absolute peach. The ...
  Nov 21, 2017

$53

$53
La Quinta Inn & Suites San Antonio Downtown

La Quinta Inn & Suites San Antonio Downtown

100 W. Cesar Chavez Blvd, San Antonio
2.5 out of 5.0
4.1 out of 5 (2,044 reviews)
It’s location is perfect near the river walk Nice, comfort, clean, big rooms, near river walk, attention is good, the food is great, and the attention is perfect, I wouldn’t think it twice to go back and stay again, thanks a lot for your perfect service
  Nov 20, 2017

$76

$76
Red Roof PLUS+ San Antonio Downtown - Riverwalk

Red Roof PLUS+ San Antonio Downtown - Riverwalk

1011 E Houston St, San Antonio
2.5 out of 5.0
3.4 out of 5 (5,386 reviews)
A clean and comfortable room I would stay here again and near River Walk and near I-40
  Nov 16, 2017

$66

$66
Hilton Palacio Del Rio

Hilton Palacio Del Rio

200 S Alamo St, San Antonio
4.0 out of 5.0
4.4 out of 5 (2,642 reviews)
Good locations near restaurants and attractions. Easy access to the River Walk.
  Nov 14, 2017

$149

$149
Comfort Suites North Ih 35

Comfort Suites North Ih 35

11526 IH 35 N, San Antonio
2.5 out of 5.0
3.9 out of 5 (84 reviews)
Ok hotel.Ok hotel situated in between a couple of bad neighborhoods.
  Nov 5, 2017

$55

$55
Stay Express Inn Lackland San Antonio

Stay Express Inn Lackland San Antonio

100 Valley Hi Dr, San Antonio
2.0 out of 5.0
2.7 out of 5 (442 reviews)
Close to workVery friendly staff. Starting a renovation that is much needed. Breakfast available but did not use.
  Nov 7, 2017

$42

$42
Map

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When you'll take your luxury hotel with a side of thrilling city attractions, you've found your niche in San Antonio. As one of the most popular destinations for adventurers who want to check out city life, San Antonio always impresses. Intriguing sites, scrumptious eats, and some of the world’s most stunning photo opportunities: these are just some of the benefits of visiting San Antonio. You'll devour fabulous cuisine, marvel at the top points of interest , and grab tickets to the most exciting shows. Of course, you'll book a room at a luxury hotel! Anything less than the best is for the birds, so get your upscale hotel in San Antonio on Expedia.com right now and start your excursion off on the right (well-dressed) foot.

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Luxury Hotels in San Antonio

It's that time; you're prepared to get swept away in The Alamo City, and Expedia.com is here to make the process painless. Search through hundreds of real traveler reviews on dozens of hotels and find the perfect vacation rental. Luxury accommodations offer amenities like stately suites and VIP services. Some of the city's 5-star accommodations even feature impeccable penthouses, while others offer rejuvenating spa treatments. Use our mobile booking app to find and book the ideal 5-star hotel in San Antonio, and soon you'll be soaking up luxury in style!