Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top San Diego County Neighborhoods for Business Hotels

The Sofia Hotel

3.5 out of 5.0
from

$125

Mission Valley
42 hotels
from

$104

Featured San Diego County Business Hotels

See all 1,372 Hotels in San Diego County
Sheraton San Diego Hotel and Marina

Sheraton San Diego Hotel and Marina

1380 Harbor Island Dr, San Diego
4.0 out of 5.0
3.9 out of 5 (2,770 reviews)
Loved itReally enjoyed the view and quiteness. Staff very prompt on room service
  Sep 19, 2017

$129

$129
Wyndham San Diego Bayside

Wyndham San Diego Bayside

1355 N Harbor Drive, San Diego
4.0 out of 5.0
3.8 out of 5 (2,578 reviews)
Great View Close to harbor, Seaport Village, and Gas Lamp District.
  Sep 20, 2017

$135

$135
Hilton San Diego Bayfront

Hilton San Diego Bayfront

1 Park Blvd, San Diego
4.0 out of 5.0
4.3 out of 5 (1,885 reviews)
Love the Bayfront!They provided a venue to Remember 9/11 Fire workers! Running 30 Flights-3 times. The lives they saved and their own lost on a day we will never forget. Thank you Hilton for never forgetting our loved ones and those that served. Respectfully, Kelley Beglin RN BSN CNRN CCRN
  Sep 11, 2017

$179

$179
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

800 Bay Marina Dr, National City
3.0 out of 5.0
4.4 out of 5 (1,069 reviews)
Nice hotel. Good location. Hotel very clean. Would like to see continental breakfast served.
  Sep 19, 2017

$135

$135
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

356 6th Avenue, San Diego
3.0 out of 5.0
4.5 out of 5 (309 reviews)
bach partyMy bridesmaids and I came to San Diego for my bachelorette party...we had so much fun and the hotel upgraded our room when they heard about my special trip. Thank you Residence Inn for fulfilling my trip.
  Sep 12, 2017

$159

$159
Marriott Vacation Club Pulse, San Diego

Marriott Vacation Club Pulse, San Diego

701 A St, San Diego
3.5 out of 5.0
4.6 out of 5 (23 reviews)
Great hotel to stay at didn't even have to driveLoved the hotel room it was super plush me and my girlfriend celebrated our 5th year anniversary and had a great time! loved the weather and everything was walking distance and the nightlife was lit!!! Definitely will come back and stay
  Sep 12, 2017

$161

$161
Best Western Seven Seas

Best Western Seven Seas

411 Hotel Circle South, San Diego
3.0 out of 5.0
3.6 out of 5 (2,530 reviews)
I love this placeMuch less expensive than most other hotels in SD. Convenient, nice staff and nice atmosphere.
  Sep 20, 2017

$104

$104
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

601 Pacific Hwy, San Diego
4.0 out of 5.0
4.1 out of 5 (681 reviews)
Like the location of the hotelThe check-in & check-out was a breeze. The room was clean, spacious and comfortable. The food was excellent. The staff were polite, respectful and helpful. The concierge and parking valets were first rate. The free breakfast and complimentary drinks in the evening were a deciding factor for selecting ...
  Sep 18, 2017

$169

$169
Super 8 San Diego Hotel Circle

Super 8 San Diego Hotel Circle

445 Hotel Cir S, San Diego
2.0 out of 5.0
3.1 out of 5 (547 reviews)
Good spotClose to seminar at Town & Country for a third of the cost is its principal value, plus two diners next door to get real food rather than a meal in a box at the forum. Beyond that, if you plan to spend anytime at the hotel or eat the free breakfast, not much to offer. Elevator was an afterthought ...
  Sep 19, 2017

$55

$55
The Westin San Diego

The Westin San Diego

400 W Broadway, San Diego
4.0 out of 5.0
4.2 out of 5 (1,082 reviews)
Welcome to Southern CaliGreat hospitality and customer service. Everyone was so welcoming; even the residents!
  Sep 17, 2017

$135

$135
Map

Recently booked Business Hotels in San Diego County

Ramada Oceanside
2.0 out of 5.0
Last booking: 1 minute ago
DoubleTree by Hilton San Diego - Del Mar
3.0 out of 5.0
Last booking: 2 minutes ago
California Suites Hotel
2.0 out of 5.0
Last booking: 2 minutes ago
Travelodge San Ysidro
2.0 out of 5.0
Last booking: 3 minutes ago
Best Western Plus Hacienda Hotel Old Town
3.0 out of 5.0
Last booking: 3 minutes ago
Consulate Hotel Airport/Sea World San Diego Area
2.0 out of 5.0
Last booking: 5 minutes ago
The Dana on Mission Bay, BW Premier Collection
3.5 out of 5.0
Last booking: 9 minutes ago
Holiday Inn Express San Diego Airport - Old Town
2.5 out of 5.0
Last booking: 11 minutes ago
Best Western Seven Seas
3.0 out of 5.0
Last booking: 12 minutes ago

San Diego County Conference Center Hotels Information

Take care of business during your stay in San Diego.

  • Choose a conference space with useful amenities for your big meeting
  • Browse the accommodations with rooms and venues to cover your needs
  • Spend more time practicing your presentation and less time hunting down deals

Stay, play, and work all in one place when you book San Diego hotels with conference centers.

These accommodations provide you with everything you need, from comfort to business amenities, during your travels in America’s Finest City. Because when you’re planning a seminar or big event, you’ll want everything at your fingertips, and these San Diego hotel conference centers offer it all.

Conference Space

Conference facilities in San Diego are ideal for your corporate events or large-scale presentations. These rental spaces provide the perfect amount of space for you to give an award-winning speech or motivate your employees during a teambuilding session. Oftentimes these conference halls also come equipped with business tools, such as Wi-Fi access and projectors.

Meeting Space

San Diego hotel conference rooms also offer smaller venues that you can reserve for more intimate meetings and presentations. Perhaps after exploring La Jolla Shores with your potential clients you’ll wow them with your sales pitch, or you want to meet with your West Coast manager in person to discuss business. These small meeting rooms provide the place to get down to business.

Allow us here at Expedia to help you reserve a business hotel with conference space in Southern California. We know you’re going to be more concerned about remembering your big speech and squeezing in some time to surf at Pacific Beach, so we make it easy for you to find accommodations suiting all your business needs. Browse our selection of accommodations and read verified hotel reviews for a hassle-free booking process.