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Featured San Francisco Boutique Hotels

See all 585 Hotels in San Francisco
Hotel Rex San Francisco

Hotel Rex San Francisco

562 Sutter St, San Francisco
4.0 out of 5.0
4.2 out of 5 (1,582 reviews)
Nice, reasonably priced older hotel in Union SqWe were very satisfied with our stay at the Hotel Rex. It is an older (I would call it an "old school" East Coast-style smaller hotel right in Union Square. The price was excellent and the room very comfortable and claen, larger than many other comparably priced SF hotels. The location is fantastic. ...
  Jan 2, 2018

$191

$191
Inn At Union Square - A Greystone Hotel

Inn At Union Square - A Greystone Hotel

440 Post St, San Francisco
3.5 out of 5.0
4.6 out of 5 (1,055 reviews)
Small hotel in great location!This is a small old hotel which has been recently nicely remodeled. The halls are narrow and the elevator is tiny but the big hearted staff is wonderful!
  Jan 18, 2018

$229

$229
Mystic Hotel by Charlie Palmer

Mystic Hotel by Charlie Palmer

417 Stockton St, San Francisco
4.0 out of 5.0
4.0 out of 5 (2,406 reviews)
Great location Nicw staff, two blocks away of Union Square, i would definitely recommend it
  Dec 27, 2017

$199

$199
Hotel Diva

Hotel Diva

440 Geary St, San Francisco
4.5 out of 5.0
3.9 out of 5 (2,814 reviews)
Great location; friendly and helpful staff. Room was just what we needed. Might be a little small for a longer stay in the City.
  Jan 15, 2018

$115

$115
Hotel Abri - Union Square

Hotel Abri - Union Square

127 Ellis Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (1,979 reviews)
Close to Union Square, great locationThe suite was a nice two room unit with a separate living room for entertaining guests. The staff was very accomodating and knew the area very well, giving recommendations as to where I can grab food and cigarettes. I stayed in this very same hotel when it was the Monticello, and had a glowing review ...
  Jan 15, 2018

$181

$181
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,489 reviews)
We stayed in transit from USA to Australia and the hotel served its purpose exceptionally. Comfortable and clean we would certainly stay again.
  Jan 18, 2018

$159

$159
Clift

Clift

495 Geary St, San Francisco
4.5 out of 5.0
4.1 out of 5 (3,460 reviews)
Nice, no frills hotel. Could do with some upgrading.
  Jan 18, 2018

$203

$203
The Marker San Francisco, a Joie de Vivre Hotel

The Marker San Francisco, a Joie de Vivre Hotel

501 Geary St, San Francisco
4.5 out of 5.0
4.4 out of 5 (2,040 reviews)
Staff was amazing, hotel and room were beautiful, location was perfect! 5 stars all around, I would highly recommend staying here!
  Jan 12, 2018

$191

$191
Villa Florence San Francisco on Union Square

Villa Florence San Francisco on Union Square

225 Powell St, San Francisco
4.0 out of 5.0
4.0 out of 5 (3,558 reviews)
Great Staff and Central LocationThe entire staff at the hotel were amazing, everyone from the front desk to the cleaning service were very friendly and helpful. The hotel's location is very centrally located and we loved the hustle and bustle of the area. Some may say the street noise it too much, but we didn't mind at all, that's ...
  Jan 8, 2018

$119

$119
Argonaut Hotel - a Noble House Hotel

Argonaut Hotel - a Noble House Hotel

495 Jefferson St, San Francisco
5.0 out of 5.0
4.6 out of 5 (5,673 reviews)
Lovely hotel, ideally situatedThe hotel is hard to fault. The location is on the wharf. The cable car stops right next to it, great restaurants all around, Golden Gate Bridge close by, Alcatraz tours etc etc. It is worth the price only minor quibble, breakfast is priced per item, as there is little to chose from in a fixed continental ...
  Jan 17, 2018

$227

$227
The Scarlet Huntington Hotel

The Scarlet Huntington Hotel

1075 California St, San Francisco
5.0 out of 5.0
4.6 out of 5 (1,549 reviews)
It’s fine, location is excellent and gives access to much more of Frisco.
  Jan 14, 2018

$269

$269
Hotel Triton

Hotel Triton

342 Grant Ave, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,429 reviews)
Strange...Overall I had a pleasant stay however they were doing construction in the lobby. The deposit rate was different on their website, it says $100 and when I checked in they tried to charge $50 per day. The room was stuffy, I couldn't open my window more than 2 inches the nailed it that way. The room ...
  Jan 16, 2018

$179

$179
Harbor Court Hotel

Harbor Court Hotel

165 Steuart St, San Francisco
4.0 out of 5.0
4.2 out of 5 (1,614 reviews)
Good Location for New Years EveStayed at Harbor Court Hotel when it first opened years ago. Decided to book a room for New Years Eve because it was right across the street from all the celebrations. What a change from over the years since our first stay when the area was in the middle of remodeling after the Embarcadero Freeway ...
  Jan 18, 2018

$180

$180
Kensington Park Hotel

Kensington Park Hotel

450 Post St, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,749 reviews)
Nice hotel close to EVERYTHINGLoved this hotel! Very old with lots of history. Check-in was smooth. Friendly staff. Valet was smooth. Our room was clean, cozy with nice decor. Yes, you can hear people through the walls/under the door "sometimes." Yes, you'll find chips and warn marks on furniture. Yes the crown molding and other ...
  Jan 17, 2018

$159

$159
Warwick San Francisco

Warwick San Francisco

490 Geary St, San Francisco
4.5 out of 5.0
4.1 out of 5 (1,314 reviews)
Good for the price but I got a special offer for $130/night. Great location. True a lot of homeless people in this area but this is a major problem of the city of San Francisco. close to shopping, great restaurants, and Metro/BART which takes you straight to the airport.
  Jan 8, 2018

$159

$159
Hotel Drisco

Hotel Drisco

2901 Pacific Avenue, San Francisco
4.5 out of 5.0
4.8 out of 5 (255 reviews)
Superb.Always a fantastic experience here. One of my absolute favourite hotel; for its attention to detail, elegant approach to everything from staff to water bottles. It’s simply the best, and most adorable!
  Dec 23, 2017

$379

$379
Hotel Adagio, Autograph Collection

Hotel Adagio, Autograph Collection

550 Geary St, San Francisco
4.5 out of 5.0
4.1 out of 5 (592 reviews)
I found a jewelNot knowing what to expect, my uber driver dropped me off at the hotel. I was pleasantly surprised with the facade, the front desk area and the interior design. Very hip. The free coffee at the elevator was perfect for just jumping out of bed, getting coffee and jumping back into bed. I found the ...
  Nov 14, 2017

$189

$189
Payne Mansion Hotel

Payne Mansion Hotel

1409 Sutter St, San Francisco
4.5 out of 5.0
3.8 out of 5 (211 reviews)
Beautiful and unique historical building in SF, clean and super nice staff.
  Jan 13, 2018

$179

$179
Taj Campton Place

Taj Campton Place

340 Stockton St, San Francisco
5.0 out of 5.0
4.6 out of 5 (919 reviews)
GREAT EXPERIENCEAS ALWAYS A GREAT HOTEL, STAFF, BAR, RESTAURANT , HOUSEKEEPING, DOOR MEN ET.
  Jan 16, 2018

$285

$285
Hotel Kabuki - a Joie de Vivre Boutique Hotel

Hotel Kabuki - a Joie de Vivre Boutique Hotel

1625 Post St, San Francisco
3.5 out of 5.0
4.1 out of 5 (3,749 reviews)
Excellent valueGreat location. Hotel is newly renovated and is great value for money. Feel like home.
  Jan 16, 2018

$229

$229
Map

Recently booked Boutique Hotels in San Francisco

Warwick San Francisco
4.5 out of 5.0
Last booking: 6 minutes ago
Hotel Kabuki - a Joie de Vivre Boutique Hotel
3.5 out of 5.0
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Bay Landing San Francisco Airport Hotel
3.0 out of 5.0
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Holiday Inn Golden Gateway
4.0 out of 5.0
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Coral Reef Inn & Suites
2.5 out of 5.0
Last booking: 12 minutes ago
Hilton San Francisco Airport Bayfront
4.5 out of 5.0
Last booking: 15 minutes ago
Omni San Francisco Hotel
5.0 out of 5.0
Last booking: 17 minutes ago
Holiday Inn Hotel & Suites San Mateo-San Francisco SFO
3.5 out of 5.0
Last booking: 17 minutes ago
Serrano Hotel
4.5 out of 5.0
Last booking: 19 minutes ago

Book a San Francisco Boutique Hotel that is Especially You

Wherever you may go, you still bring your exceptional self with you, and Expedia offers great rates at the most avant-garde and authentic designer rooms in San Francisco. Once you've landed in San Francisco, there will be no question that this city offers excitement around every crowd-filled corner. Although San Francisco has a large population, you will not run into a lot of travelers, so you'll have noissues feeling like a local. San Francisco was ranked in Expedia's top 10 of must-see destinations, so you know that there will be lots to keep you busy.

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  • A highly personalized type of service, where they add thoughtful touches like fresh flowers.
  • A prime address in the entertaining part of the city. You'll be moments away from the town's best sites.

Indulge in Everything San Francisco Offers!

San Francisco has a large number of rooms to select from, but you wish for something more than a commonplace accommodation. San Francisco has accommodations to please most anyone that that can make your visit unforgettable.

Book Some Designer Digs in San Francisco

Seeing as how there are tons of lodgings to decide from, it can be tricky to pick the right one. Expedia helps whittle down the options with loads of ratings, reviews, and pictures, so you can choose the best San Francisco boutique hotel that adds the finishing touches on your trip. Whether you want to stay in a fun and cool place or a luxury one that indulges you, your perfect boutique hotel is just a few clicks away.