Beginning of main content

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured San Francisco Boutique Hotels

See all 543 Hotels in San Francisco
Hotel Rex San Francisco

Hotel Rex San Francisco

562 Sutter St, San Francisco
4.0 out of 5.0
4.2 out of 5 (1,599 reviews)
The hotel is within easy walking distance to restaurants and Union Square. Staff members were friendly and helpful.
  Feb 13, 2018

$116

$116
Inn At Union Square - A Greystone Hotel

Inn At Union Square - A Greystone Hotel

440 Post St, San Francisco
4.0 out of 5.0
4.6 out of 5 (1,065 reviews)
Rooms are pleasant. Staff is great. Charming smaller boutique hotel.
  Dec 8, 2017

$209

$209
Mystic Hotel

Mystic Hotel

417 Stockton St, San Francisco
3.5 out of 5.0
4.0 out of 5 (2,425 reviews)
Nice rooms, clean and friendly staffSome rooms are small, but very comfortable and super clean. Ask for a room away from the alley, as the garbage truck noise in the am resonates quite a bit. Location is great and very convenient for downtown SFO.
  Jan 29, 2018

$157

$157
Hotel Diva

Hotel Diva

440 Geary St, San Francisco
4.5 out of 5.0
3.9 out of 5 (2,835 reviews)
Check in was very easy. To park your car is $55/day with unlimited in/out privileges. Rooms are a good size.
  Feb 16, 2018

$106

$106
Hotel Abri - Union Square

Hotel Abri - Union Square

127 Ellis Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,979 reviews)
Friendly and accommodating staffWe stayed only overnight and were extremely pleased with the friendly staff and lovely room. We would have liked to have been able to open the windows, though. It was around the corner from the Powell and Hyde cable car stop and from Union Square. Shopping, restaurants and several museums were within ...
  Feb 7, 2018

$151

$151
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (2,580 reviews)
Good and badHandy for the Wharf and nice out there decor. But walls are paper thin - could hear every time the lift arrived on our floor. All in all decent though.
  Feb 17, 2018

$161

$161
Clift

Clift

495 Geary St, San Francisco
4.5 out of 5.0
4.1 out of 5 (3,483 reviews)
Hotel close to financial districtComfortable studio, very comfy bed. All’s good with this hotel!
  Feb 13, 2018

$195

$195
The Marker San Francisco, a Joie de Vivre Hotel

The Marker San Francisco, a Joie de Vivre Hotel

501 Geary St, San Francisco
4.5 out of 5.0
4.4 out of 5 (2,039 reviews)
Cute, quirky hotel for good priceGot a good deal on Expedia and it was good location for my business meetings.
  Feb 14, 2018

$143

$143
Villa Florence San Francisco on Union Square

Villa Florence San Francisco on Union Square

225 Powell St, San Francisco
4.5 out of 5.0
4.0 out of 5 (3,572 reviews)
This is a convenient place to stay in the San Francisco downtown. Just a bit noisy.
  Feb 15, 2018

$135

$135
Argonaut Hotel - a Noble House Hotel

Argonaut Hotel - a Noble House Hotel

495 Jefferson St, San Francisco
4.5 out of 5.0
4.6 out of 5 (5,709 reviews)
Great Location!Very nice hotel, with great views and access to the Piers. Just around the corner from the trolly to Union Square and Lombard Hill. We would definitely stay here again!
  Feb 16, 2018

$203

$203
The Scarlet Huntington Hotel

The Scarlet Huntington Hotel

1075 California St, San Francisco
5.0 out of 5.0
4.6 out of 5 (1,570 reviews)
Great location I love old world charm. This hotel is gorgeous. The room was beautiful & quaint. Great shower!! The complimentary town car is a wonderful touch. We are definitely staying here again. The hotel bar is a neighborhood watering hole, great for meeting locals. We sat in the park across the street, soaked ...
  Feb 16, 2018

$292

$292
Hotel Triton

Hotel Triton

342 Grant Ave, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,451 reviews)
Boutique hotel next to Chinatown and Union SquareThe hotel recently changed ownership, therefore, there’s construction going on in the lobby area. The lobby looks nothing like the website photos and they should be taken down. The lobby consists of a structure for a desk, some chairs and a fireplace in a tight construction area. The staff was professional ...
  Feb 13, 2018

$129

$129
Harbor Court Hotel

Harbor Court Hotel

165 Steuart St, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,624 reviews)
Comfortable beds, being refurbishedI've stayed at the Harbor Court on business trips several times over the last few years, and return because of the convenient location, comfortable beds and pleasant staff. Rooms are clean but a little on the small side; this time I ended up in a refurbished room which felt nice and fresh. There ...
  Feb 10, 2018

$140

$140
Kensington Park Hotel

Kensington Park Hotel

450 Post St, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,755 reviews)
Great location, helpful staff, clean rooms. Had lovely stay in San Francisco!!
  Feb 14, 2018

$135

$135
Warwick San Francisco

Warwick San Francisco

490 Geary St, San Francisco
4.5 out of 5.0
4.1 out of 5 (1,323 reviews)
Great, quaint stay right downtownAlthough I have visited San Francisco many times, this was my first visit here. The staff that greeted me was wonderful, and the experience never waned. The room had a fireplace, was clean and comfortable, and I slept soundly on a very good mattress. Even the pillows were above par, unusual in my ...
  Feb 6, 2018

$155

$155
Hotel Drisco

Hotel Drisco

2901 Pacific Avenue, San Francisco
4.5 out of 5.0
4.8 out of 5 (256 reviews)
Superb.Always a fantastic experience here. One of my absolute favourite hotel; for its attention to detail, elegant approach to everything from staff to water bottles. It’s simply the best, and most adorable!
  Dec 23, 2017

$399

$399
Hotel Adagio, Autograph Collection

Hotel Adagio, Autograph Collection

550 Geary St, San Francisco
4.5 out of 5.0
4.1 out of 5 (593 reviews)
I found a jewelNot knowing what to expect, my uber driver dropped me off at the hotel. I was pleasantly surprised with the facade, the front desk area and the interior design. Very hip. The free coffee at the elevator was perfect for just jumping out of bed, getting coffee and jumping back into bed. I found the ...
  Nov 14, 2017

$179

$179
Payne Mansion Hotel

Payne Mansion Hotel

1409 Sutter St, San Francisco
4.0 out of 5.0
3.8 out of 5 (215 reviews)
Nice hotel and a lot of privacyIt was great overall. It had all the right amenities. My bed and room was fantastic especially my pillow. There were still road noises near by. But it didn't bother me as much. The only downside for me was the breakfast. I thought we would get a little more for our money. Hard boil eggs aren't bad. ...
  Jan 31, 2018

$157

$157
Taj Campton Place

Taj Campton Place

340 Stockton St, San Francisco
5.0 out of 5.0
4.6 out of 5 (924 reviews)
Very friendly and accommodating staffThe rooms are nice. Well lit with a good amount of space. The bathrooms are large. Tub and shower. The shower heads are ok. All in all the room seems a little dated. The worst part about the hotel was the mattresses very uncomfortable and needed update now!
  Feb 5, 2018

$285

$285
Hotel Kabuki - a Joie de Vivre Boutique Hotel

Hotel Kabuki - a Joie de Vivre Boutique Hotel

1625 Post St, San Francisco
4.5 out of 5.0
4.1 out of 5 (3,773 reviews)
New favorite hotel for San FranciscoI travel for business a lot - and to San Francisco a lot - and was bored with the usual places I've stayed. Hotel Kabuki was a great change and a wonderful hotel. Each member of the staff was friendly and genuinely helpful from front desk staff to the bar team. The lobby is a wonderful comfortable ...
  Feb 15, 2018

$181

$181

Recently booked Boutique Hotels in San Francisco

Galleria Park Hotel, a Joie de Vivre Boutique Hotel
4.5 out of 5.0
Last booking: 17 minutes ago
Best Western Plus El Rancho Inn
3.5 out of 5.0
Last booking: 27 minutes ago
Castle Inn
2.0 out of 5.0
Last booking: 31 minutes ago
Hotel Zelos San Francisco
4.5 out of 5.0
Last booking: 38 minutes ago
Holiday Inn Express San Francisco-Airport North
3.0 out of 5.0
Last booking: 39 minutes ago
Calista Organic Hotel
3.5 out of 5.0
Last booking: 39 minutes ago
Pacific Inn of Redwood City
3.0 out of 5.0
Last booking: 44 minutes ago
Comfort Inn by the Bay
3.0 out of 5.0
Last booking: 1 hour ago
Coral Reef Inn & Suites
3.0 out of 5.0
Last booking: 1 hour ago

Book a San Francisco Boutique Hotel that is Especially You

Wherever you may go, you still bring your exceptional self with you, and Expedia offers great rates at the most avant-garde and authentic designer rooms in San Francisco. Once you've landed in San Francisco, there will be no question that this city offers excitement around every crowd-filled corner. Although San Francisco has a large population, you will not run into a lot of travelers, so you'll have noissues feeling like a local. San Francisco was ranked in Expedia's top 10 of must-see destinations, so you know that there will be lots to keep you busy.

Small Property with Colossal Character

With your chic style and a desire to follow your own path, part of the perfect traveling experience is discovering a location in San Francisco that reflects you. Unlike huge chain hotels that try to satisfy everybody, these smaller hotels have no trouble flaunting their individuality. Most boutique hotels have characteristics like:

  • An exclusive stay, as boutique hotels ordinarily have fewer than 100 rooms. These smaller accommodations are ideal when you need to get away from the bustle and have a little me time.
  • An idiosyncratic style that you just will not be able to be able to get in larger hotels, from individually designed rooms to intimate cafes, and amenities that make them feel extremely comfortable.
  • A highly personalized type of service, where they add thoughtful touches like fresh flowers.
  • A prime address in the entertaining part of the city. You'll be moments away from the town's best sites.

Indulge in Everything San Francisco Offers!

San Francisco has a large number of rooms to select from, but you wish for something more than a commonplace accommodation. San Francisco has accommodations to please most anyone that that can make your visit unforgettable.

Book Some Designer Digs in San Francisco

Seeing as how there are tons of lodgings to decide from, it can be tricky to pick the right one. Expedia helps whittle down the options with loads of ratings, reviews, and pictures, so you can choose the best San Francisco boutique hotel that adds the finishing touches on your trip. Whether you want to stay in a fun and cool place or a luxury one that indulges you, your perfect boutique hotel is just a few clicks away.