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Featured San Francisco Independent Hotels

See all 521 Hotels in San Francisco
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
4.0 out of 5.0
3.2 out of 5 (8,258 reviews)
Lot of bums in the area, but besides that everything is good - 

$105

$105
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
4.0 out of 5.0
4.0 out of 5 (4,159 reviews)
SF Nostalgia We loved staying here, brought back many memories of old times living in SF! Hotel stay was great i … - 

$129

$129
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.5 out of 5.0
4.0 out of 5 (4,490 reviews)
Nice stay here at the Serrano Hotel in San Francisco!! - 

$138

$138
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,399 reviews)
Close to everything We had a great experience at Hotel Zephyr. Staff at front desk was very helpful. They even took the … - 

$161

$161
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.5 out of 5.0
4.5 out of 5 (3,668 reviews)
Nice stay in Burlingame Friendly staff, good location, great breakfast, comfortable room. Would definitely stay again. - 

$112

$112
Hotel Focus SFO

Hotel Focus SFO

111 Mitchell Ave, South San Francisco
3.0 out of 5.0
3.1 out of 5 (383 reviews)
Comfortable hotel close to SFO Worked out well for our 9 hr layover. Clean, quiet, attentive staff and breakfast included. Shuttle … - 

$89

$89
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

433 Powell St, San Francisco
3.5 out of 5.0
4.3 out of 5 (3,562 reviews)
Good location with accessibility to multi forms of public transportation. Comfortable room and free … - 

$107

$107
Hotel Aura SFO

Hotel Aura SFO

190 El Camino Real, San Bruno
2.5 out of 5.0
4.0 out of 5 (1,936 reviews)
Free shuttle, Free Breakfast, and close to airport - 

$90

$90
Lombard Motor Inn

Lombard Motor Inn

1475 Lombard Street, San Francisco
3.0 out of 5.0
4.0 out of 5 (1,683 reviews)
Nice Close to bus stops and delicious eateries around. - 

$97

$97
Hotel EPIK

Hotel EPIK

706 Polk St, San Francisco
4.0 out of 5.0
3.8 out of 5 (431 reviews)
Nice property close to Opera, symphony Very clean modern and great for a quick overnight for a show or business. Great staff. Maybe the on … - 

$84

$84
Grant Hotel

Grant Hotel

753 Bush St, San Francisco
2.5 out of 5.0
3.6 out of 5 (2,695 reviews)
Small pleasant room Convenient lower cost Parker ng clos to the best of Sf - 

$79

$79
The Pickwick Hotel

The Pickwick Hotel

85 5th St, San Francisco
4.0 out of 5.0
3.6 out of 5 (1,894 reviews)
Excellent and helpful staff. Helpful and courteous staff. The rooms are in good condition but subject to street noise, they do n … - 

$117

$117
The Dylan at SFO

The Dylan at SFO

110 S El Camino Real, Millbrae
3.5 out of 5.0
4.1 out of 5 (2,537 reviews)
Comfortable hotel with great transportation access Easy check in, friendly staff, and comfortable room. The breakfast is good for a free breakfast too … - 

$99

$99
The Andrews Hotel

The Andrews Hotel

624 Post St, San Francisco
3.5 out of 5.0
3.8 out of 5 (1,353 reviews)
We stayed at the Andrews while attending a three-day conference in SF. A simple continental breakfa … - 

$92

$92
King George Hotel - A Greystone Hotel

King George Hotel - A Greystone Hotel

334 Mason Street, San Francisco
3.5 out of 5.0
3.8 out of 5 (2,187 reviews)
Close to everything! Went for an Oakland Raiders game and to unwind a bit! Hotel is in a great location, with awesome st … - 

$97

$97
Hotel Fusion, a C-Two Hotel

Hotel Fusion, a C-Two Hotel

140 Ellis Street, San Francisco
4.0 out of 5.0
3.7 out of 5 (2,011 reviews)
Stayed for 3 nights for a conference. Extremely convenient location for sightseeing of the city. Ho … - 

$119

$119
Monarch Hotel

Monarch Hotel

1015 Geary St, San Francisco
2.5 out of 5.0
3.0 out of 5 (1,918 reviews)
Comfortable hotel not so far from Downtown Hotel with a very nice view over the city (sixth floor) and not so far from the city center. It is … - 

$93

$93
Park Pointe Hotel

Park Pointe Hotel

245 S Airport Blvd, South San Francisco
2.5 out of 5.0
3.1 out of 5 (257 reviews)
Nice and quiet hotel close to the airport. Check in staff are very friendly and efficient. Hotel is very clean and I love their concrete bedro … - 

$94

$94
Grant Plaza Hotel

Grant Plaza Hotel

465 Grant Ave, San Francisco
2.5 out of 5.0
3.2 out of 5 (2,008 reviews)
Fairly well located - within walking distance to union square/Market St. The room was small but fai … - 

$89

$89
Villa Florence San Francisco on Union Square

Villa Florence San Francisco on Union Square

225 Powell St, San Francisco
4.5 out of 5.0
4.0 out of 5 (3,527 reviews)
Valet not ideal I have to say the very beginning of my stay was NOT good. However, it turned around rather quickly … - 

$118

$118
Map

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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.