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San Francisco Hotel Rooms at the Independent

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San Francisco Hotels

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Featured San Francisco Independent Hotels

See all 479 Hotels in San Francisco
Cavallo Point

Cavallo Point

601 Murray Circle, Sausalito
4.5 out of 5.0
4.4 out of 5 (121 reviews)
Great location, comfortable rooms We spent 2 nights in a Historical King Suite and really enjoyed our stay. The location is phenomena … - 

$529

$529
Orchard Garden Hotel

Orchard Garden Hotel

466 Bush St, San Francisco
4.0 out of 5.0
4.5 out of 5 (607 reviews)
Nice Quiet Close to Chinatown Union Square Tourist Attractions Restaurants. QUIET. - 

$179

$179
Orchard Hotel

Orchard Hotel

665 Bush St, San Francisco
4.0 out of 5.0
4.6 out of 5 (801 reviews)
Great Location, Friendly/Helpful Staff Very comfortable, great staff, and great location. Excellent stay! - 

$179

$179
Axiom Hotel San Francisco

Axiom Hotel San Francisco

28 Cyril Magnin Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (146 reviews)
Prime location Lovely boutique hotel in the heart of Union Square - 

$182

$182
Villa Florence

Villa Florence

225 Powell St, San Francisco
4.0 out of 5.0
3.7 out of 5 (505 reviews)
Loved this Hotel! Great Stay Everything was clean. Great Room. Loved the location. Great price - 

$140

$140
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,504 reviews)
small hotel near to public transport was excellent. loved the golden bridge and golden park - 

$168

$168
Casa Madrona Hotel & Spa

Casa Madrona Hotel & Spa

801 Bridgeway, Sausalito
3.5 out of 5.0
4.3 out of 5 (188 reviews)
Great location and views Harborside room on the 4th floor was clean, roomy, and comfortable. Really enjoyed the views and cl … - 

$237

$237
Hotel G San Francisco

Hotel G San Francisco

386 Geary Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (467 reviews)
Awesome stay Great location, steps from union square and plenty of food options nearby. Room was really pretty a … - 

$178

$178
Oceano Hotel and Spa

Oceano Hotel and Spa

280 Capistrano Road, Half Moon Bay
4.0 out of 5.0
4.4 out of 5 (267 reviews)
Wonderful relaxing accomadations Very clean well kept property, room was spacious and well equipped. We enjoyed our stay and will be … - 

$259

$259
Hotel Drisco

Hotel Drisco

2901 Pacific Avenue, San Francisco
4.0 out of 5.0
4.8 out of 5 (117 reviews)
Deluxe, luxury Hotel This is probably the nicest hotel that I've ever stayed in. It might be one of the nicest hotels in … - 
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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.