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Featured San Francisco Independent Hotels

See all 585 Hotels in San Francisco
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
4.0 out of 5.0
3.2 out of 5 (8,344 reviews)
Inspect the room when you get there!! The hotel is really nice despite bad reviews about bedbugs and such on YELP. I took a chance with m … - 

$115

$115
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.0 out of 5.0
4.5 out of 5 (3,708 reviews)
Great hotel Bay Landing is a lovely hotel. The room was very clean and that made it comfortable and worry free. … - 

$98

$98
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.5 out of 5.0
4.0 out of 5 (4,554 reviews)
Nice hotel. Great staff I got in very early and was allowed to check in which really made my day much better. It's under re … - 

$139

$139
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,491 reviews)
We stayed in transit from USA to Australia and the hotel served its purpose exceptionally. Comforta … - 

$159

$159
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
4.0 out of 5.0
4.0 out of 5 (4,203 reviews)
Nice Hotel close to Union Square. Highly recommend. Polite staff and pleasing accommodations. They have taken good care to maintain a … - 

$159

$159
Hotel Aura SFO

Hotel Aura SFO

190 El Camino Real, San Bruno
2.5 out of 5.0
4.0 out of 5 (1,959 reviews)
Quick easy SFO stay Much more price friendly than the waterfront SFO hotels. Was fine to spend the night before a 6am f … - 

$100

$100
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

433 Powell St, San Francisco
3.5 out of 5.0
4.3 out of 5 (3,586 reviews)
Excellent location Great central location in union square, walking distance to central city attractions - 

$109

$109
Hotel Focus SFO

Hotel Focus SFO

111 Mitchell Ave, South San Francisco
3.5 out of 5.0
3.1 out of 5 (417 reviews)
Nice hotel near to airport Very nice hotel near to San Francisco airport. Rooms are clean and comfortable. Free shutlle. - 

$99

$99
Grant Hotel

Grant Hotel

753 Bush St, San Francisco
2.5 out of 5.0
3.6 out of 5 (2,718 reviews)
The overall experience is okay for the price. When I travel I'm rarely in the hotel room unless it' … - 

$109

$109
Lombard Motor Inn

Lombard Motor Inn

1475 Lombard Street, San Francisco
3.0 out of 5.0
4.0 out of 5 (1,699 reviews)
Great location great staff Great value for money in a good location. Super helpful staff who gave us an early check in and gre … - 

$106

$106
Grant Plaza Hotel

Grant Plaza Hotel

465 Grant Ave, San Francisco
2.5 out of 5.0
3.2 out of 5 (2,033 reviews)
Nice, Clean Hotel Hotel is nice, beds were comfortable. Rooms were clean - 

$109

$109
The Andrews Hotel

The Andrews Hotel

624 Post St, San Francisco
3.5 out of 5.0
3.8 out of 5 (1,378 reviews)
A Well Run and Maintained Antique Staff was friendly and helpful, rooms were kept clean, the old elevator felt solid, and the old sta … - 

$119

$119
Axiom Hotel San Francisco

Axiom Hotel San Francisco

28 Cyril Magnin Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (606 reviews)
Great location but super noisy Wanted to rate this hotel higher because of the location room quality overall decor is excellent... … - 

$165

$165
Hotel EPIK

Hotel EPIK

706 Polk St, San Francisco
4.0 out of 5.0
3.8 out of 5 (462 reviews)
Austin did a great job. Very friendly n professional! - 

$120

$120
The Pickwick Hotel

The Pickwick Hotel

85 5th St, San Francisco
4.0 out of 5.0
3.6 out of 5 (1,891 reviews)
Horel is very old, small room and small bathroom. Lobby and check-in/out experience very nice. Park … - 

$149

$149
Hotel Fusion, a C-Two Hotel

Hotel Fusion, a C-Two Hotel

140 Ellis Street, San Francisco
3.5 out of 5.0
3.7 out of 5 (2,015 reviews)
Good hotel in the center of San Francisco An average/good hotel in the center of San Francisco. Hotel seems to be a bit old and some of it pa … - 

$159

$159
The Dylan at SFO

The Dylan at SFO

110 S El Camino Real, Millbrae
3.0 out of 5.0
4.1 out of 5 (2,582 reviews)
Very convenient to airport We had an early morning flight, this hotel was perfectly located. It was a clean, quiet and comfort … - 

$108

$108
Villa Florence San Francisco on Union Square

Villa Florence San Francisco on Union Square

225 Powell St, San Francisco
4.0 out of 5.0
4.0 out of 5 (3,558 reviews)
Great Staff and Central Location The entire staff at the hotel were amazing, everyone from the front desk to the cleaning service we … - 

$119

$119
The Mosser

The Mosser

54 4th Street, San Francisco
3.0 out of 5.0
3.9 out of 5 (4,400 reviews)
2nd stay at Mosser I stayed at The Mosser from Jan 8-11 2018 for a conference. The location was fantastic for activity … - 

$101

$101
Park Pointe Hotel

Park Pointe Hotel

245 S Airport Blvd, South San Francisco
2.5 out of 5.0
3.1 out of 5 (303 reviews)
Very good shuttle service close to the airport stays open all night - 

$104

$104
Map

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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.