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Featured San Francisco Independent Hotels

See all 509 Hotels in San Francisco
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.1 out of 5 (3,186 reviews)
Fantastic historic property with a Grand lobby Fantastic historic property with Grand Lobby filled with marble, massive wood details and massive d … - 

$189

$189
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,813 reviews)
A short stat in San Fran CBD Well located across from union square, excellent facilities including fitness centre, quiet rooms a … - 

$245

$245
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,611 reviews)
Hotel Serrano was close to Union Square, big bus pickup and bike rentals. Around 10 minute walk to … - 

$208

$208
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,358 reviews)
holiday lovely stay here. Place spotless, doors opened for you, nothing too much trouble. Staff lovely.Ate … - 

$203

$203
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,268 reviews)
ambiance good We're happy even it was a short stay, we get to lounge outside the hotel comfortably, less noise, c … - 

$219

$219
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.0 out of 5.0
4.5 out of 5 (2,128 reviews)
Easy check in. Close to airport. Great Breakfast. Convenient airport shuttle. - 

$152

$152
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,753 reviews)
Excellent service great location near everything Will stay again. - 

$194

$194
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,053 reviews)
Atop Beautiful Nob Hill While we had an interior view room, there are so many great views from everywhere you go around nea … - 

$280

$280
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.1 out of 5 (880 reviews)
The Zephyr is a nice hotel in a central location Booked though Expedia and had a trouble-free experience for 5 nights in a two-bed nice room on 2nd … - 

$212

$212
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,912 reviews)
Hotel close to a lot tourist spot Modern hotel with clean rooms, decent breakfast buffet and it's close to a lot of tourist spots and … - 

$220

$220
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

424 Clay St, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,407 reviews)
Great location awesome staff! Nice clean room with everything we needed! I would for sure stay here … - 

$161

$161
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,641 reviews)
Nice Stay, Decent Service Too long a wait to check in with so many staff working at 8 pm Sunday night. Place was not that bus … - 

$199

$199
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
3.5 out of 5.0
3.9 out of 5 (1,583 reviews)
Handlery - location, location, location! Great location at Union Square. Handy to trolleys, restaurants, shopping, tours, cable cars. We ask … - 

$199

$199
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,369 reviews)
A great vacation We had a great stay. It was our first trip to San Francisco. I chose this hotel because of its loca … - 

$229

$229
Red Roof PLUS+ San Francisco Airport

Red Roof PLUS+ San Francisco Airport

777 Airport Blvd, Burlingame
3.0 out of 5.0
3.4 out of 5 (1,009 reviews)
ccomfort, even though we checked out we were still able to use the airport shuttle pool and shower … - 

$121

$121
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (1,535 reviews)
Wouldn't hesitate to recommend this wonderful hotel. Staff are excellent and willing to go the extr … - 

$235

$235
San Francisco Marriott Union Square

San Francisco Marriott Union Square

480 Sutter Street, San Francisco
4.0 out of 5.0
4.3 out of 5 (765 reviews)
Great location We stayed 3 nights. The room is starting to look a little dated but still lovely, bathroom good siz … - 

$209

$209
Hotel Kabuki - a Joie de Vivre Boutique Hotel

Hotel Kabuki - a Joie de Vivre Boutique Hotel

1625 Post St, San Francisco
3.5 out of 5.0
4.1 out of 5 (1,100 reviews)
Fun Hotel, complimentary wine! We've enjoyed this hotel before and had a great time again. Staff super friendly and accommodating. … - 

$151

$151
Bartlett Bunkhouse

Bartlett Bunkhouse

240 O'Farrell St, San Francisco
2.5 out of 5.0
3.9 out of 5 (32 reviews)
Close to central city Room was small but clean. No view, double bed, not so comfy. Good internet, recently updated room. … - 

$129

$129
Map

Recently booked San Francisco hotels

Handlery Union Square Hotel
3.5 out of 5.0
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Hotel Whitcomb
3.5 out of 5.0
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Four Points by Sheraton San Francisco Bay Bridge
3.0 out of 5.0
Last booking: 9 minutes ago
Stanford Court San Francisco
4.0 out of 5.0
Last booking: 10 minutes ago

Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.