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San Francisco Hotel Rooms at the Independent

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Featured San Francisco Independent Hotels

See all 495 Hotels in San Francisco
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,557 reviews)
Nice older hotel in a great location Ok, the Serrano is an older hotel, and it shows a little wear. But it still is a great place to sta … - 

$158

$158
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
3.5 out of 5.0
3.9 out of 5 (1,535 reviews)
Door condition is not good. Door for bathroom does not close. Room is good, location is excellent. - 

$169

$169
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.1 out of 5 (3,112 reviews)
it was close to our final destination, Lighthouse good restaurant's abound on site and off. Nice bar, beautiful really. close to things downtown like … - 

$169

$169
The Westin St Francis San Francisco on Union Square

The Westin St Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,769 reviews)
Fantastic Location. No complaints here, a well run hotel close to everything and a good deal found on Expedia. Don't ex … - 

$195

$195
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,005 reviews)
It was nice staying at such a historic hotel. It's a good central location that we were able to use … - 

$299

$299
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.1 out of 5 (835 reviews)
Location is so great for Fisherman's Wharf and the Pier 39 and locations nearby. All within easy wa … - 

$179

$179
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,341 reviews)
Great hotel and a super location We loved our stay. Our room was super comfortable and immaculate! We were on the 24th floor with a … - 

$209

$209
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,606 reviews)
Great hotel We stayed an entire week at the Marriott Marquis and our stay was awesome. Great location and the s … - 

$170

$170
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,232 reviews)
Nothing noticeable Staff was attentive to our family needs. Room was clean but the lay out was a little uncomfortable … - 

$109

$109
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,818 reviews)
Great+location+and+amazing+breakfast%21 The+hotel+has+thin+walls+and+can+get+very+noisy+which+can+make+it+hard+to+sleep.+Other+than+that+th … - 

$175

$175
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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.