Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured San Francisco Independent Hotels

See all 507 Hotels in San Francisco
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
    4.0 out of 5.0
     
     
    4.0 out of 5 (4,716 reviews)
    Very nice hotel! We had a comfortable and convenient stay. Clean rooms, polite staff, great location - in the heart … - 

    Serrano Hotel$105

    Serrano Hotel$105
    Hotel Whitcomb

    Hotel Whitcomb

    1231 Market St, San Francisco
      3.5 out of 5.0
       
       
      3.2 out of 5 (8,588 reviews)
      Although the area is not the best, the hotel was a nice, comfortable stay. For a short trip stay I … - 

      Hotel Whitcomb$119

      Hotel Whitcomb$119
      Bay Landing San Francisco Airport Hotel

      Bay Landing San Francisco Airport Hotel

      1550 Bayshore Hwy, Burlingame
        3.0 out of 5.0
         
         
        4.5 out of 5 (3,822 reviews)
        The hotel staff were very welcoming. I arrived early and they were able to get me into a room right … - 

        Bay Landing San Francisco Airport Hotel$116

        Bay Landing San Francisco Airport Hotel$116
        Hotel Focus SFO

        Hotel Focus SFO

        111 Mitchell Ave, South San Francisco
          3.0 out of 5.0
           
           
          3.1 out of 5 (517 reviews)
          Overalll satisfied Great location near most main downtown and entertainment locations the staff is friendly the contin … - 

          Hotel Focus SFO$97

          Hotel Focus SFO$97
          Hotel Zephyr

          Hotel Zephyr

          250 Beach Street, San Francisco
            3.5 out of 5.0
             
             
            4.2 out of 5 (2,756 reviews)
            Creative home run hurt by cost cutting operations This is a three and a half star hotel. I would stay again,and I would recommend it to you or a frie … - 

            Hotel Zephyr$169

            Hotel Zephyr$169
            Chancellor Hotel on Union Square

            Chancellor Hotel on Union Square

            433 Powell St, San Francisco
              3.5 out of 5.0
               
               
              4.3 out of 5 (3,705 reviews)
              Location, clean, value Hotel is on a sensational hotel across the road feom the bustling hub of union sq. Cable car right … - 

              Chancellor Hotel on Union Square$143

              Chancellor Hotel on Union Square$143
              Handlery Union Square Hotel

              Handlery Union Square Hotel

              351 Geary St, San Francisco
                3.5 out of 5.0
                 
                 
                4.0 out of 5 (4,275 reviews)
                Great pool! Great location, helpful staff, and cool, old historic charm. The pool was fantastic, but you might … - 

                Handlery Union Square Hotel$149

                Handlery Union Square Hotel$149
                The Pickwick Hotel

                The Pickwick Hotel

                85 5th St, San Francisco
                  3.5 out of 5.0
                   
                   
                  3.5 out of 5 (1,930 reviews)
                  Good location, decent room, nice staff...would stay again for business travel. - 

                  The Pickwick Hotel$139

                  The Pickwick Hotel$139
                  Hotel Aura SFO

                  Hotel Aura SFO

                  190 El Camino Real, San Bruno
                    2.0 out of 5.0
                     
                     
                    4.0 out of 5 (2,003 reviews)
                    Affordable, convenient, to SFO Needed a place close to SFO for a short 1 night stay. Shuttle was great, room was clean but a bit w … - 

                    Hotel Aura SFO$100

                    Hotel Aura SFO$100
                    Hotel Vertigo

                    Hotel Vertigo

                    940 Sutter Street, San Francisco
                      3.5 out of 5.0
                       
                       
                      4.0 out of 5 (1,495 reviews)
                      simpatico hotel nice hotel not especially expensive in a expensive but great city - 
                      Mystic Hotel

                      Mystic Hotel

                      417 Stockton St, San Francisco
                        3.5 out of 5.0
                         
                         
                        4.0 out of 5 (2,470 reviews)
                        Nice, hip hotel with friendly staff I had a good experience and would probably stay there again. I just had minor complaints like the N … - 

                        Mystic Hotel$155

                        Mystic Hotel$155
                        Monarch Hotel

                        Monarch Hotel

                        1015 Geary St, San Francisco
                          2.0 out of 5.0
                           
                           
                          3.0 out of 5 (1,947 reviews)
                          Perfect location. Love staying here. Staff is so nice. We always stay here - 

                          Monarch Hotel$117

                          Monarch Hotel$117
                          The Dylan at SFO

                          The Dylan at SFO

                          110 S El Camino Real, Millbrae
                            3.0 out of 5.0
                             
                             
                            4.1 out of 5 (2,676 reviews)
                            Cozy Boutique Hotel Close to SFO Charming boutique hotel super close to SFO in Millbrae. Rooms have been recently updated in a styli … - 

                            The Dylan at SFO$108

                            The Dylan at SFO$108
                            Grant Plaza Hotel

                            Grant Plaza Hotel

                            465 Grant Ave, San Francisco
                              2.0 out of 5.0
                               
                               
                              3.2 out of 5 (2,086 reviews)
                              Great location. Rooms are small but clean. Overall good experience - 

                              Grant Plaza Hotel$123

                              Grant Plaza Hotel$123
                              Lombard Motor Inn

                              Lombard Motor Inn

                              1475 Lombard Street, San Francisco
                                2.5 out of 5.0
                                 
                                 
                                4.0 out of 5 (1,733 reviews)
                                What a deal! This is the BEST inexpensive hotel in the wharf area, bar none. Free parking when everyone else cha … - 
                                Grant Hotel

                                Grant Hotel

                                753 Bush St, San Francisco
                                  2.0 out of 5.0
                                   
                                   
                                  3.6 out of 5 (2,799 reviews)
                                  Quaint and cozy hotel. Old building but the staff were very friendly and kept it clean. - 
                                  Axiom Hotel San Francisco

                                  Axiom Hotel San Francisco

                                  28 Cyril Magnin Street, San Francisco
                                    4.0 out of 5.0
                                     
                                     
                                    4.4 out of 5 (676 reviews)
                                    Nice hotel. The only thing I didn’t like was the area it was in. The staff is friendly. And room wa … - 
                                    The Mosser

                                    The Mosser

                                    54 4th Street, San Francisco
                                      2.5 out of 5.0
                                       
                                       
                                      3.9 out of 5 (4,447 reviews)
                                      Enjoyable stsy My stay was enjoyable. However there were a few episodes of cigarette smoke coming into my room, an … - 
                                      Francisco Bay Inn

                                      Francisco Bay Inn

                                      1501 Lombard St, San Francisco
                                        2.0 out of 5.0
                                         
                                         
                                        3.4 out of 5 (1,761 reviews)
                                        24hour trip The girls attending front desk have a wonderful personality and people skills. I would defiantly st … - 

                                        Francisco Bay Inn$119

                                        Francisco Bay Inn$119
                                        Inn on Broadway

                                        Inn on Broadway

                                        2201 Van Ness Avenue, San Francisco
                                          2.5 out of 5.0
                                           
                                           
                                          3.2 out of 5 (1,662 reviews)
                                          Good location The hotel location is good with walking distance to reach Chinatown and Fisherman’s Wharf. The room … - 
                                          Map

                                          Recently booked San Francisco hotels

                                          Casa Loma Hotel
                                          2.0 out of 5.0
                                          Last booking: 18 minutes ago
                                          Mystic Hotel
                                          3.5 out of 5.0
                                          Last booking: 32 minutes ago
                                          Hotel Kabuki - a Joie de Vivre Boutique Hotel
                                          4.0 out of 5.0
                                          Last booking: 35 minutes ago
                                          Vagabond Inn Executive San Francisco Airport
                                          2.5 out of 5.0
                                          Last booking: 36 minutes ago
                                          Days Inn San Francisco International Airport West
                                          2.5 out of 5.0
                                          Last booking: 39 minutes ago
                                          Americas Best Value Inn San Mateo/San Francisco
                                          2.0 out of 5.0
                                          Last booking: 46 minutes ago
                                          King George Hotel - A Greystone Hotel
                                          3.0 out of 5.0
                                          Last booking: 47 minutes ago
                                          Hotel Nikko San Francisco
                                          4.0 out of 5.0
                                          Last booking: 48 minutes ago
                                          Clift
                                          4.0 out of 5.0
                                          Last booking: 49 minutes ago

                                          Independent San Francisco Hotel Guide

                                          Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

                                          You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.