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Featured San Francisco Independent Hotels

See all 509 Hotels in San Francisco
The Tuscan, A Noble House Hotel

The Tuscan, A Noble House Hotel

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,352 reviews)
Staff was very polite and receptive. Gave us each a glass of wine at registration and a bag of popc … - 

$203

$203
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (1,535 reviews)
Wouldn't hesitate to recommend this wonderful hotel. Staff are excellent and willing to go the extr … - 

$235

$235
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.1 out of 5 (3,184 reviews)
CONVENIENTLY LOCATED HOTEL WAS GREAT FOR GETTING ON THE BART AND THE F TRAIN, IT WAS NICE THAT THEY HAD PARKING, BUT THE … - 

$189

$189
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.0 out of 5.0
4.5 out of 5 (2,122 reviews)
Nice hotel next to water Chose this hotel because of the great deal for applying expedia points. So not sure about its norma … - 

$143

$143
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
3.5 out of 5.0
3.9 out of 5 (1,581 reviews)
Great hotel in a great location Walking distance to a lot of restaurants, Walgreens and shops. Could walk to Chinatown but its hill … - 

$199

$199
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,290 reviews)
Great hotel, great location, does not include breakfast and fruits in the gym, but aside that all w … - 

$229

$229
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,610 reviews)
Always a pleasant stay We've stayed here 3 times over the past couple of years. It's a great location with convenient park … - 

$208

$208
San Francisco Marriott Union Square

San Francisco Marriott Union Square

480 Sutter Street, San Francisco
4.0 out of 5.0
4.3 out of 5 (764 reviews)
Good hotel for the price. Clean and staff are friendly. - 

$209

$209
Red Roof PLUS+ San Francisco Airport

Red Roof PLUS+ San Francisco Airport

777 Airport Blvd, Burlingame
3.0 out of 5.0
3.4 out of 5 (1,008 reviews)
ccomfort, even though we checked out we were still able to use the airport shuttle pool and shower … - 

$121

$121
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,051 reviews)
Although we had to pay top dollar due to high occupancy, our room was wonderful ! - 

$280

$280
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,752 reviews)
Great but expensive Very clean and very comfortable! Only complaint is regarding the terrible out-of-control homeless s … - 

$194

$194
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,641 reviews)
Nice Stay, Decent Service Too long a wait to check in with so many staff working at 8 pm Sunday night. Place was not that bus … - 

$199

$199
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,905 reviews)
great place! Excellent location, clean, staff very friendly. Very good experience overall, room was larger than … - 

$220

$220
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.1 out of 5 (873 reviews)
Very artsy hotel with paper thin walls The hotel is gorgeous. If you are looking to stay in a boutique hotel with amazing art and guests f … - 

$237

$237
Hotel Kabuki - a Joie de Vivre Boutique Hotel

Hotel Kabuki - a Joie de Vivre Boutique Hotel

1625 Post St, San Francisco
3.5 out of 5.0
4.1 out of 5 (1,099 reviews)
Fun Hotel, complimentary wine! We've enjoyed this hotel before and had a great time again. Staff super friendly and accommodating. … - 

$151

$151
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,267 reviews)
Great stay Staff were fantastic and helpful. Restaurant was good and not overpriced. Only negative was that on … - 

$179

$179
The Westin St Francis San Francisco on Union Square

The Westin St Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,809 reviews)
Location location location I took my son to San Francisco for his 25 Birthday since he never been there before. I booked this … - 

$245

$245
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,364 reviews)
Close to everything My SF experience was great. The only disappointment was we never were allowed to go up to the 36th … - 

$229

$229
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

424 Clay St, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,406 reviews)
Clean but service levels low. Requested extra towel and wine glasses for two days, never came. Over … - 

$161

$161
Bunkhouse

Bunkhouse

240 O'Farrell St, San Francisco
2.5 out of 5.0
3.9 out of 5 (28 reviews)
Good location near to everything It's a good place for those who want to explore San Francisco, public transportation, bars, restaur … - 

$129

$129
Map

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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.