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San Francisco Hotel Rooms at the Independent

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Featured San Francisco Independent Hotels

See all 495 Hotels in San Francisco
The Westin St Francis San Francisco on Union Square

The Westin St Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,770 reviews)
Great location to stay when visiting San Francisco Excellent location to take in all the sites in San Francisco. Easy access from SFO on the BART or a … - 

$195

$195
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,007 reviews)
Our stay in San Francisco We had lovely time! What an amazing hotel. We had a marvelous time. - 

$299

$299
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.1 out of 5 (837 reviews)
Small rooms , not fresh clean sheets. Hotel need some updates,small rooms for 4 people . - 

$179

$179
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,342 reviews)
nice hotel in the center of downtown. Very nice hotel! We were in the center of all the activities, the staff was kind, the hotel was cle … - 

$209

$209
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,609 reviews)
Luxurious and affordable. Perfect hotel for a weekend vacation. Hotel staff was attententive and nice enough to upgrade mine … - 

$170

$170
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,234 reviews)
Week end stay Came for sad occasion but your staff made it easier for me. Quick service smiles everywhere. - 

$109

$109
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,820 reviews)
Nice hotel with small fixable flaw Hotel is in a great location. The bed is comfortable, the decor is nice and the tv is huge. However … - 

$175

$175
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,559 reviews)
Great location! Enjoyed our stay at this hotel. It is centrally located near Union Square and close to everything. … - 

$158

$158
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
3.5 out of 5.0
3.9 out of 5 (1,535 reviews)
Door condition is not good. Door for bathroom does not close. Room is good, location is excellent. - 

$169

$169
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.1 out of 5 (3,112 reviews)
it was close to our final destination, Lighthouse good restaurant's abound on site and off. Nice bar, beautiful really. close to things downtown like … - 

$169

$169
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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.