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Featured San Francisco Independent Hotels

See all 525 Hotels in San Francisco
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.3 out of 5 (8,231 reviews)
Good customer service from all staff. Good location too - 

$105

$105
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (5,631 reviews)
Nice, clean hotel. Near to a lot of things. Nice experience.Hotel was clean and safe. I would go back! - 

$179

$179
Sheraton Fisherman's Wharf Hotel

Sheraton Fisherman's Wharf Hotel

2500 Mason St, San Francisco
4.0 out of 5.0
3.8 out of 5 (3,919 reviews)
Nice hotel It was confortable and very clean! Close to the beach and many attractions - 

$149

$149
Clift

Clift

495 Geary St, San Francisco
4.5 out of 5.0
4.1 out of 5 (3,438 reviews)
Great location Nice hotel and redwood room bar Bathroom needs help. More storage and better ventilation. It was al … - 

$159

$159
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.5 out of 5.0
4.0 out of 5 (3,250 reviews)
Room condition is good,need better foods for breakfast. Environment is good and I like the bed, ver … - 

$99

$99
Larkspur Landing South San Francisco - An All-Suite Hotel

Larkspur Landing South San Francisco - An All-Suite Hotel

690 Gateway Blvd, South San Francisco
3.5 out of 5.0
4.1 out of 5 (1,915 reviews)
Overall nice hotel Overall, nice place to stay. it has a full kitchen and breakfast is great. - 

$101

$101
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.5 out of 5.0
4.3 out of 5 (6,513 reviews)
Wonderful experience! The staff is incredibly friendly and my room was gorgeous, pristine and comfo … - 

$157

$157
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center, San Francisco
4.0 out of 5.0
4.3 out of 5 (3,167 reviews)
Andy at ceck in provided World class service to me andy family - 

$159

$159
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.5 out of 5.0
4.2 out of 5 (4,370 reviews)
Excellent hotel. Excellent hotel. Street noise and traffic getting into this section of San Francisco were the only … - 

$158

$158
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (3,029 reviews)
Comfortable hotel I love staying at the Palace Hotel. The beds and pillows are so comfortable and the rooms are spaci … - 

$167

$167
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (4,084 reviews)
Family weekend getaway It was a total of 18 of us and we all loved the hotel, room, delicious breakfast and most important … - 

$161

$161
Holiday Inn San Francisco-Fisherman's Wharf

Holiday Inn San Francisco-Fisherman's Wharf

1300 Columbus Ave, San Francisco
3.5 out of 5.0
3.9 out of 5 (4,988 reviews)
Great location and friendly staff. The hotel was in a great location. The staff was very nice. The only downside was the room had an o … - 

$126

$126
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.5 out of 5.0
4.4 out of 5 (3,338 reviews)
Nice hotel, great location! Great trip! Fantastic hotel. Close to shops and restaraunts. - 

$169

$169
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.5 out of 5 (3,842 reviews)
Great hotel in beautiful San Francisco. Only downside is that you have to walk up a big hill! - 

$199

$199
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
4.0 out of 5.0
4.0 out of 5 (4,153 reviews)
SF Nostalgia We loved staying here, brought back many memories of old times living in SF! Hotel stay was great i … - 

$129

$129
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.5 out of 5.0
4.0 out of 5 (4,478 reviews)
Room was nice, restaurant staff terrible The staff were pleasant, Room perfect. Clean I had a nice view of the city. Restaurant - I only ate … - 

$168

$168
The Park Central San Francisco

The Park Central San Francisco

50 3rd St, San Francisco
4.5 out of 5.0
4.3 out of 5 (5,872 reviews)
Thanksgiving in the city Took the family to the city for a get away thanksgiving weekend. Very nice hotel but expect to pay … - 

$114

$114
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,380 reviews)
This is my second time at the Zepher nice room clean. Good location. SF Wharf. - 

$161

$161
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.5 out of 5.0
4.5 out of 5 (3,660 reviews)
Good value Older, but nice and very clean hotel in the SFO area. They had a shuttle from the airport which was … - 

$112

$112
Hotel Focus SFO

Hotel Focus SFO

111 Mitchell Ave, South San Francisco
3.5 out of 5.0
3.1 out of 5 (374 reviews)
Nice and clean It’s was close to everything. Very neat and clean. - 

$89

$89
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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.