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Featured San Francisco Independent Hotels

See all 500 Hotels in San Francisco
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.1 out of 5 (3,188 reviews)
Classic hotel with a nice feel and very good restaurant. Have stayed there several times and I find … - 

$189

$189
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,815 reviews)
Great hotel in the middle of everything. Clean, comfortable, and in the middle of everywhere you'd want to be. It's an older hotel, so rooms … - 

$245

$245
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,613 reviews)
Very nice stay in great location. The Serrano Hotel is a great, historical hotel with tons of character. It is located very near to U … - 

$228

$228
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,359 reviews)
Close to the Wharf Nothing ‘tourist-ty’ in the immediate block - 

$203

$203
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,268 reviews)
ambiance good We're happy even it was a short stay, we get to lounge outside the hotel comfortably, less noise, c … - 

$219

$219
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.0 out of 5.0
4.5 out of 5 (2,129 reviews)
Everyhing was nice. Only issue was with the internet connection. - 

$161

$161
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,754 reviews)
Hotel Stay Experience was outstanding! Would definitely stay again. Ernesto, the concierge was amazing! Hotel … - 

$194

$194
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,055 reviews)
Beautiful historic hotel We enjoyed our stay here. the lobby is really beautiful. They accept dogs, so this was a big plus f … - 

$280

$280
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.1 out of 5 (879 reviews)
The Zephyr is a nice hotel in a central location Booked though Expedia and had a trouble-free experience for 5 nights in a two-bed nice room on 2nd … - 

$212

$212
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,917 reviews)
Great hotel, great location, very clean, very coastal/modern feeling in the rooms, welcoming and st … - 

$237

$237
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

424 Clay St, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,408 reviews)
sometimes employee staff make all the difference i had some billing issues; Sarbi at the hotel took care of them and that made all the difference. B … - 

$161

$161
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,642 reviews)
Large modern hotel located centrally Very efficient hotel where everything worked and staff were helpful. An easy walk to Union Square a … - 

$199

$199
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
3.5 out of 5.0
3.9 out of 5 (1,583 reviews)
Handlery - location, location, location! Great location at Union Square. Handy to trolleys, restaurants, shopping, tours, cable cars. We ask … - 

$199

$199
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,372 reviews)
Really nice hotel in downtown San Francisco Really nice hotel in downtown San Francisco. clean room, nice staff. great location. working distan … - 

$229

$229
Red Roof PLUS+ San Francisco Airport

Red Roof PLUS+ San Francisco Airport

777 Airport Blvd, Burlingame
3.0 out of 5.0
3.4 out of 5 (1,009 reviews)
ccomfort, even though we checked out we were still able to use the airport shuttle pool and shower … - 

$121

$121
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (1,537 reviews)
Overall experience was good but parking was expensive. - 

$235

$235
San Francisco Marriott Union Square

San Francisco Marriott Union Square

480 Sutter Street, San Francisco
4.0 out of 5.0
4.3 out of 5 (765 reviews)
Great location We stayed 3 nights. The room is starting to look a little dated but still lovely, bathroom good siz … - 

$209

$209
Hotel Kabuki - a Joie de Vivre Boutique Hotel

Hotel Kabuki - a Joie de Vivre Boutique Hotel

1625 Post St, San Francisco
3.5 out of 5.0
4.1 out of 5 (1,100 reviews)
Fun Hotel, complimentary wine! We've enjoyed this hotel before and had a great time again. Staff super friendly and accommodating. … - 

$167

$167
Bartlett Bunkhouse

Bartlett Bunkhouse

240 O'Farrell St, San Francisco
2.5 out of 5.0
3.9 out of 5 (36 reviews)
Good reasonable convenient hotel Great forr the city centre - clean and comfortable - 

$129

$129
Map

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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.